Acute Exercise for Breast Cancer

Penn State Hershey Medical Center, Hershey, PA
Breast CancerAcute Exercise - Behavioral
18 - 80

Study Summary

This trial is looking at how physical activity affects breast cancer patients by looking at changes in the tumor, how much oxygen it gets, and the levels of circulating tumor DNA and exerkines.

Treatment Effectiveness

Study Objectives

4 Primary · 5 Secondary · Reporting Duration: baseline or before cardiopulmonary exercise (CPET), immediately after CPET (an average of 12 min following baseline), 30 min following CPET, and 2 hours following CPET

Hour 2
Changes in ctDNA level
Changes in deoxy-hemoglobin
Changes in oxy-hemoglobin
Changes in oxygen saturation
Changes in total hemoglobin
Exerkine: S1P
Exerkine: TGF-β
Exerkine: TSP-1
Exerkine: VEGF-A

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Acute exercise
1 of 1

Experimental Treatment

30 Total Participants · 1 Treatment Group

Primary Treatment: Acute Exercise · No Placebo Group · N/A

Acute exercise
Experimental Group · 1 Intervention: Acute Exercise · Intervention Types: Behavioral
First Studied
Drug Approval Stage
How many patients have taken this drug
Acute Exercise

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
469 Previous Clinical Trials
2,785,977 Total Patients Enrolled
11 Trials studying Breast Cancer
568 Patients Enrolled for Breast Cancer
Kathleen Sturgeon, PhD, MEd, MSPrincipal InvestigatorPenn state University College of Medicine

Eligibility Criteria

Age 18 - 80 · Female Participants · 14 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are pregnant.
You may have a condition called dissecting aneurysm.
You have a sudden medical condition that may affect or worsen with exercise, but is not related to the heart or lungs.
You have a history of fainting.
You currently have acute endocarditis (infection of the heart).
You have recently had inflammation of the heart muscle or the lining surrounding the heart.
You have a blood clot in your legs.
You have asthma that is not properly managed.
You have unstable chest pain.
People under the age of 18.
You have an irregular heartbeat that is not under control and causes symptoms or affects your blood flow.
You have a heart condition that is not well managed.
You are experiencing serious breathing problems.
You are not able to make informed decisions by yourself.

Frequently Asked Questions

Does this trial permit participants of all ages, or are there age restrictions?

"This trial is open to individuals aged 18 or older, but no more than 80 years old." - Anonymous Online Contributor

Unverified Answer

Are there any eligibility criteria which would disqualify me from participating in this trial?

"The prerequisites for being accepted into this clinical trial mandate that patients are between 18 and 80 years old and have been diagnosed with breast cancer. A total of 30 enrollees will be admitted to the experiment." - Anonymous Online Contributor

Unverified Answer

How many subjects are participating in this clinical trial?

"Affirmative. The website reveals that this medical trial is presently looking for 30 test subjects across one site, and it was initially posted on July 29th 2022 with the most recent edit made on August 17th of the same year." - Anonymous Online Contributor

Unverified Answer

Are there any vacancies available for participants of this research endeavor?

"Affirmative. records specify that this medical experiment is currently seeking participants; it was initially posted on July 29th 2022 and its details have been revised as recently as August 17th of the same year. 30 subjects need to be identified from a single site for inclusion in the research study." - Anonymous Online Contributor

Unverified Answer

What goals is this research study attempting to achieve?

"This trial's main objective is to observe changes in oxy-hemoglobin levels over four periods: the baseline, 12 minutes post-baseline, 30 minutes post-baseline and two hours post-baseline. In addition to this primary outcome, secondary objectives also encompass tracking alterations in ctDNA level, TGF-β concentration and S1P presence across these same points of time." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.