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Acute Exercise for Breast Cancer (WISER-WIN Trial)

N/A

Waitlist Available

Led By Kathleen Sturgeon, PhD, MEd, MS

Research Sponsored by Milton S. Hershey Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet

Awards & highlights

WISER-WIN Trial Summary

This trial is looking at how physical activity affects breast cancer patients by looking at changes in the tumor, how much oxygen it gets, and the levels of circulating tumor DNA and exerkines.

WISER-WIN Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline or before cardiopulmonary exercise (cpet), immediately after cpet (an average of 12 min following baseline), 30 min following cpet, and 2 hours following cpet for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in deoxy-hemoglobin

Changes in oxy-hemoglobin

Changes in oxygen saturation

+1 more

Secondary outcome measures

Changes in ctDNA level

Exerkine: S1P

Exerkine: TGF-β

+2 more

WISER-WIN Trial Design

1Treatment groups

Experimental Treatment

Group I: Acute exerciseExperimental Treatment1 Intervention

Participants will be asked to walk or jog on a treadmill for a maximal exercise test.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Acute Exercise

2022

Completed Phase 3

~30

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor

492 Previous Clinical Trials

2,798,819 Total Patients Enrolled

13 Trials studying Breast Cancer

602 Patients Enrolled for Breast Cancer

Kathleen Sturgeon, PhD, MEd, MSPrincipal InvestigatorPenn state University College of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this trial permit participants of all ages, or are there age restrictions?

"This trial is open to individuals aged 18 or older, but no more than 80 years old."

Answered by AI

Are there any eligibility criteria which would disqualify me from participating in this trial?

"The prerequisites for being accepted into this clinical trial mandate that patients are between 18 and 80 years old and have been diagnosed with breast cancer. A total of 30 enrollees will be admitted to the experiment."

Answered by AI

How many subjects are participating in this clinical trial?

"Affirmative. The clinicaltrial.gov website reveals that this medical trial is presently looking for 30 test subjects across one site, and it was initially posted on July 29th 2022 with the most recent edit made on August 17th of the same year."

Answered by AI

Are there any vacancies available for participants of this research endeavor?

"Affirmative. Clinicaltrials.gov records specify that this medical experiment is currently seeking participants; it was initially posted on July 29th 2022 and its details have been revised as recently as August 17th of the same year. 30 subjects need to be identified from a single site for inclusion in the research study."

Answered by AI

What goals is this research study attempting to achieve?

"This trial's main objective is to observe changes in oxy-hemoglobin levels over four periods: the baseline, 12 minutes post-baseline, 30 minutes post-baseline and two hours post-baseline. In addition to this primary outcome, secondary objectives also encompass tracking alterations in ctDNA level, TGF-β concentration and S1P presence across these same points of time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Women In Steady Exercise Research - Window of Opportunity for Exercise and Tumor Biology

Kathleen Sturgeon 2023. "Women In Steady Exercise Research - Window of Opportunity for Exercise and Tumor Biology". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05428709.