Microwave Imaging for Breast Follow-up

EF
AG
Overseen ByAnita Garland Study coordinator
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: University of Calgary
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how a new microwave imaging technology, WVI-MIS-02-2025, can measure and analyze breast tissue, particularly for women needing further tests after a mammogram. The researchers aim to compare these microwave images with traditional mammogram data, focusing on identifying areas of concern. Women who have had a mammogram in the last six weeks and require additional imaging due to specific findings might be suitable candidates. Participants will have their breasts scanned up to three times during follow-up appointments and will complete surveys about their breast health and scanning experience. As an unphased trial, this study allows participants to contribute to the development of innovative imaging technology that could enhance breast cancer diagnostics.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. However, since the trial is focused on imaging and not treatment, it's unlikely that you would need to stop any medications.

What prior data suggests that this microwave imaging technique is safe for breast follow-up?

Research has shown that microwave imaging for breast check-ups is generally safe. One study found that this method does not significantly heat breast tissue, making it unlikely to cause harm. Another study on using microwaves to detect breast cancer reported that patients handled the process well, with no major side effects.

The device used in this trial, WVI-MIS-02-2025, captures images of the breast using microwaves. These microwaves are similar to those in everyday items like Wi-Fi and cell phones, which are considered safe. Participants in past studies have undergone similar procedures without problems, suggesting this trial is likely safe for participants.12345

Why are researchers excited about this trial?

Researchers are excited about the trial for Microwave Imaging for Breast Follow-up because it offers a non-invasive and radiation-free alternative to traditional imaging methods like mammograms and MRIs. This technique uses microwave technology to capture images, which could be more comfortable and safer for patients. Additionally, it has the potential to provide quicker and more detailed insights into breast health, helping doctors make more informed decisions about patient care.

What evidence suggests that this microwave imaging technique is effective for breast follow-up?

Research shows that microwave imaging is a promising tool for checking breast health. In earlier studies, this method successfully found and pinpointed most breast lumps, whether harmless or cancerous. One study found that it detected 9 out of 11 breast cancers, including some that did not appear on regular mammograms. Additionally, microwave imaging uses non-ionizing waves, making it safer than other imaging methods that use radiation. This trial will evaluate the WVI-MIS-02-2025 device, which could also help in tracking breast cancer treatment and screening.678910

Are You a Good Fit for This Trial?

This trial is for women who have been asked to return for follow-up breast imaging. Participants will undergo additional microwave scans using the WVI-MIS-02-2025 technology, alongside their scheduled mammograms.

Inclusion Criteria

Able to provide informed consent
Had a screening mammogram within the previous 6 weeks
Recalled for additional breast imaging due to BIRADS 3 or 4 findings.
See 2 more

Exclusion Criteria

Participants who have not received a mammogram
Participants with breast implants
Participants who are pregnant or breastfeeding
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging and Data Collection

Participants undergo microwave imaging and mammogram comparison during their follow-up breast imaging appointment

1 day
1 visit (in-person)

Data Analysis

Analysis of collected microwave and mammogram data to compare electrical properties and image registration

12 months

Follow-up

Participants are monitored for any additional imaging needs or safety concerns

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • WVI-MIS-02-2025

Trial Overview

The study tests if microwave images can be compared with mammograms in terms of positioning and tissue properties. It aims to see if these new scans can identify anomalies like a mammogram does, by scanning each breast up to three times.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: WVI-MIS-02-2025Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials
827
Recruited
902,000+

Pureform Radiology

Collaborator

Wave View Imaging Inc.

Collaborator

Citations

Wavelia Microwave Breast Imaging Phase#2 Clinical ...

The use of Digital Breast Tomosynthesis (DBT) and deep-learning (DL) computer-aided detection (CAD) software has improved outcomes on mammogram readings of ...

A Novel Microwave Imaging System for Early Detection of ...

We developed SAFE (Scan and Find Early), a microwave imaging device that uses non-ionizing electromagnetic waves to detect breast cancer safely and effectively.

NCT03475992 | Pilot Clinical Study on a Low-power ...

Microwave imaging can potentially be used for monitoring neoadjuvant chemotherapy treatment, breast health monitoring, and for routine screening and diagnosis ...

Microwave imaging for monitoring breast cancer treatment: A ...

This study aims to detect treatment-related changes in breast tissue with a low-resolution microwave scanner.

Microwave Imaging in Breast Cancer – Results from the ...

The MBI system detected and localised 12 of 13 benign breast lesions, and 9 out of the 11 breast cancers. This included 1 case of a radiographically occult ...

Microwave Imaging for Breast Follow-up · Info for Participants

This N/A medical study run by University of Calgary needs participants to evaluate whether WVI-MIS-02-2025 will have tolerable side effects & efficacy for ...

Assessing Patient-Specific Microwave Breast Imaging in ...

In this work, a leading approach for dielectric properties estimation based on the computation of many candidate images for microwave breast ...

Safety Assessment of Microwave Breast Imaging

Safety Assessment of Microwave Breast Imaging: Heating Analysis on Digital Breast ... health-software/ accessed on 9 April 2025) [21]. Models #2 ( ...

Microwave Imaging for Breast Cancer Detection

Microwave imaging has been proposed for breast cancer detection and treatment monitoring. Prototype systems based on tomography and radar-based techniques ...

Results from Clinical Investigation of the SAFE Microwave ...

Breast microwave imaging devices tested on human subjects. ... follow-up surveillance imaging for 5 years. Analyzing the Database ...