Microwave Imaging for Breast Follow-up

Overseen By Anita Garland Study coordinator

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: University of Calgary

Disqualifiers: Breast cancer treatment, Breast implants, Pregnant, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical trial is to measure the electrical properties of breast tissues using microwave technology and to compare these collected measurements to clinical information in mammograms for women that have been recalled for follow-up breast imaging. The main questions it aims to answer are:

1. Can the breast area and plate separation in the microwave scan be compared to mammogram data to assess similarity in breast positioning and the feasibility of image registration?

2. Can the distribution of electrical properties specifically glandular tissue distribution in the microwave image be compared to that observed in the mammogram?

3. Can the characteristics of the microwave image in the localized region corresponding to an identified anomaly in the mammogram be examined?

Study participants will be scanned with the Wave View microwave scanner on the same day as their follow-up breast imaging appointment. Each breast will be scanned up to 3 times with the scanner oriented in both the horizontal position and oriented at 45 degrees. Study participants will also be asked to fill out three surveys, one relating to breast health and the other two relating to their scanning experience.

Are You a Good Fit for This Trial?

This trial is for women who have been asked to return for follow-up breast imaging. Participants will undergo additional microwave scans using the WVI-MIS-02-2025 technology, alongside their scheduled mammograms.

Inclusion Criteria

Able to provide informed consent

Had a screening mammogram within the previous 6 weeks

Recalled for additional breast imaging due to BIRADS 3 or 4 findings.

Exclusion Criteria

Participants who have not received a mammogram

Participants with breast implants

Participants who are pregnant or breastfeeding

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Imaging and Data Collection

Participants undergo microwave imaging and mammogram comparison during their follow-up breast imaging appointment

1 day

1 visit (in-person)

Data Analysis

Analysis of collected microwave and mammogram data to compare electrical properties and image registration

12 months

Follow-up

Participants are monitored for any additional imaging needs or safety concerns

4 weeks

What Are the Treatments Tested in This Trial?

Trial Overview The study tests if microwave images can be compared with mammograms in terms of positioning and tissue properties. It aims to see if these new scans can identify anomalies like a mammogram does, by scanning each breast up to three times.

How Is the Trial Designed?

Group I: WVI-MIS-02-2025 Experimental Treatment 1 Intervention

A single arm study in which the collected microwave data is compared against available clinical data.

Who Is Running the Clinical Trial?

University of Calgary

Lead Sponsor

Trials

827

Recruited

902,000+

Pureform Radiology

Collaborator

Wave View Imaging Inc.

Collaborator