Ashwagandha for Menopause
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests the effectiveness of two different ashwagandha extracts in alleviating menopause symptoms, such as hot flashes and hormone levels, compared to a placebo. Participants will take either a daily ashwagandha supplement or a placebo for 84 days. The researchers aim to determine if ashwagandha can effectively relieve menopause symptoms. Women who still have regular periods and experience hot flashes might be suitable candidates. As an unphased trial, this study provides an opportunity to contribute to the understanding of natural remedies for menopause symptoms.
Will I have to stop taking my current medications?
Yes, if you are currently taking thyroid medications, blood pressure drugs, medications for the central nervous system, diabetes medications, benzodiazepines, or immunosuppressants, you will need to stop taking them at least 60 days before joining the study.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that ashwagandha is generally safe for most people. The root and leaf extract can be used safely for up to three months. Common side effects include stomach upset and drowsiness, while serious problems are rare.
One study found that using the root extract for 12 months did not harm the liver or kidneys, suggesting it is safe for long-term use. However, some individuals have experienced skin issues like itching and burning, which resolved after discontinuing the supplement.
Overall, both extracts appear safe for most people, but consulting a healthcare provider before starting any new supplement is always wise.12345Why are researchers excited about this trial's treatments?
Researchers are excited about using ashwagandha for menopause because it offers a natural alternative to hormone replacement therapy and other medications typically used to manage menopausal symptoms. Ashwagandha, a plant-based remedy, is known for its adaptogenic properties, which may help balance stress hormones and improve overall well-being. This treatment stands out because it uses active ingredients from ashwagandha roots and leaves, which are thought to enhance its effectiveness. Unlike synthetic drugs, ashwagandha is derived from a natural source, potentially offering a gentler option with fewer side effects.
What evidence suggests that ashwagandha extract could be effective for menopause?
Research has shown that ashwagandha root extract can help relieve mild to moderate menopause symptoms, such as hot flashes and mood swings. In this trial, one group of participants will take an ashwagandha root supplement, while another group will receive a combination of ashwagandha root and leaf extracts. Previous studies found that women who took ashwagandha experienced noticeable improvements in their symptoms compared to those who took a placebo. Ashwagandha may also improve sleep quality and reduce stress, common issues during menopause. Another study found that using both ashwagandha root and leaf extracts helped reduce menopause symptoms and improved overall well-being. These findings suggest that ashwagandha could be a promising option for managing menopause symptoms.46789
Are You a Good Fit for This Trial?
This trial is for women aged 40 to 55 experiencing menopause symptoms, who menstruate regularly and have certain hormone levels. They must not have liver, kidney, hormonal or heart issues, recent weight changes or allergies to the treatment components. Participants should agree to lifestyle guidelines and contraception use.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants take one of two ashwagandha extracts or a placebo daily for 84 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Ashwagandha Extract
Trial Overview
The study tests two proprietary ashwagandha extracts against a placebo in reducing menopausal symptoms like hot flashes. It's randomized and double-blinded, meaning neither researchers nor participants know who receives the actual extract versus the placebo.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Placebo Group
Participants in this arm will take an ashwagandha root and leaf supplement each day for 84 days.
Participants in this arm will take an ashwagandha root supplement each day for 84 days.
Participants in this arm will take an inert placebo each day for 84 days.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nutraceuticals Research Institute
Lead Sponsor
Citations
The Effectiveness of a Proprietary Ashwagandha Extract on ...
The purpose of this study is to evaluate the efficacy of two proprietary ashwagandha extracts on symptoms of menopause and hormone levels, as ...
A randomized, double-blind, placebo-controlled study
These findings suggest that ashwagandha root extract can be a safe and effective option to relieve mild to moderate climacteric symptoms during perimenopause ...
A Randomized, Double-Blind, Placebo-Controlled Study
Ashwagandha and Shatavari Extracts Dose-Dependently Reduce Menopause Symptoms, Vascular Dysfunction, and Bone Resorption in Postmenopausal ...
Is Withania somnifera (Ashwagandha) a safe and effective ...
Results Findings indicate that WS can significantly improve vasomotor symptoms, psychological well-being, sleep quality, cognition, stress ...
5.
nutraingredients.com
nutraingredients.com/Article/2021/10/27/Ashwagandha-root-extract-shows-efficacy-for-menopausal-symptoms/Ashwagandha root extract shows efficacy for menopausal ...
For the 91 women who completed the study, the data showed that women in the ashwagandha group experienced statistically significant reductions ...
Ashwagandha: Is it helpful for stress, anxiety, or sleep?
Ashwagandha appears to be well tolerated for up to about 3 months of use, but its long-term safety is not known. Common side effects (e.g., ...
Ashwagandha - Uses, Side Effects, and More
When applied to the skin: Lotion containing ashwagandha is possibly safe when used for up to 2 months. Pregnancy: It is likely unsafe to use ashwagandha when ...
Ashwagandha
Ashwagandha is used in Ayurvedic formulations for stress, strain, fatigue, pain, skin disease, diabetes, gastrointestinal disease, ...
Ashwagandha for menopause: Benefits, risks, and safety
Some small studies suggest ashwagandha may reduce hot flashes, but there are potential risks. Learn more about ashwagandha and menopause.
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