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Cued Picture-Naming Therapy for Aphasia

N/A
Recruiting
Led By Stacy M Harnish, PhD
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Native English Speaker.
At least six months post-onset of a single left-hemisphere stroke
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 months
Awards & highlights

Study Summary

This trial will investigate whether genes and cognitive abilities predict responsiveness to aphasia therapy for word-retrieval difficulties.

Who is the study for?
This trial is for native English speakers who have chronic aphasia, specifically difficulty retrieving words (anomia), due to a single left-hemisphere stroke that occurred at least six months ago. It's not suitable for those with severe comprehension issues, depression, MRI contraindications like pacemakers or metal implants, claustrophobia, pregnancy, severe speech disorders, widespread brain damage or uncorrected vision/hearing problems.Check my eligibility
What is being tested?
The study is exploring the effectiveness of cued picture-naming therapy in treating word-retrieval difficulties in people with aphasia. It aims to determine if two specific genes and cognitive abilities such as memory can predict how well someone will respond to this treatment.See study design
What are the potential side effects?
Since the intervention involves non-invasive therapy sessions focused on language recovery rather than medication or surgery, there are no direct physical side effects expected from the cued picture-naming therapy itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am a native English speaker.
Select...
It has been over 6 months since my stroke in the left side of my brain.
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I struggle to find the right words when speaking.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent of pictures named correctly
Percentage of pictures named correctly
Secondary outcome measures
Percentage of untrained pictures named correctly
percentage of definitions named correctly

Trial Design

1Treatment groups
Experimental Treatment
Group I: Single Arm TreatmentExperimental Treatment1 Intervention
Cued picture naming therapy will be delivered to all participants. There will be four cohorts of participants based on BDNF and ApoE genotypes.

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor
835 Previous Clinical Trials
508,641 Total Patients Enrolled
1 Trials studying Aphasia
20 Patients Enrolled for Aphasia
Nationwide Children's HospitalOTHER
341 Previous Clinical Trials
5,220,386 Total Patients Enrolled
Stacy M Harnish, PhDPrincipal InvestigatorOhio State University

Media Library

Cued picture-naming therapy Clinical Trial Eligibility Overview. Trial Name: NCT05179538 — N/A
Aphasia Research Study Groups: Single Arm Treatment
Aphasia Clinical Trial 2023: Cued picture-naming therapy Highlights & Side Effects. Trial Name: NCT05179538 — N/A
Cued picture-naming therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT05179538 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the protocol for this trial permit enrolment of persons below thirty years old?

"This clinical trial has an age limit of 18 or above and 85 or below for prospective participants."

Answered by AI

Is it possible to enlist in this clinical research endeavor?

"To be eligible for this research, candidates must have an aphasic diagnosis and fall within the 18 to 85 age bracket. The trial aims to enrol 120 individuals in total."

Answered by AI

What is the current number of participants enrolled in this clinical study?

"Affirmative. According to clinicaltrials.gov, recruitment for this medical trial is ongoing since its initiation on October 23rd 2020 and the most recent update made on September 2nd 2022. The study requires 120 participants from a single site."

Answered by AI

Is the recruitment process for this medical trial still open?

"Affirmative. According to the information hosted on clinicaltrials.gov, this research initiative which was first published on October 23rd 2020 is actively recruiting participants. The enrolment of 120 patients from a single site needs to be completed soon."

Answered by AI

Who else is applying?

What site did they apply to?
The Ohio State University
What portion of applicants met pre-screening criteria?
Met criteria

Why did patients apply to this trial?

to possibly help my speech.
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
Genetic and Cognitive Predictors of Aphasia Treatment Response
2020. "Genetic and Cognitive Predictors of Aphasia Treatment Response". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05179538.
All > Aphasia
~29 spots leftby Aug 2025
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