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Procedure

tACS for Aphasia

N/A

Waitlist Available

Research Sponsored by University of Pennsylvania

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Presence of aphasia

Suffered a single, left hemisphere stroke

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 5-10 minutes after a single session of active (alpha tacs) and sham (fake tacs).

Awards & highlights

Study Summary

This trial tests if tACS can improve language skills in post-stroke aphasia, and see if it is different to aged matched controls.

Who is the study for?

This trial is for right-handed individuals who have had a stroke in the left hemisphere of their brain at least 6 months ago and are now experiencing aphasia, which affects language abilities. They must understand the study and agree to participate.Check my eligibility

What is being tested?

Researchers are testing if active transcranial alternating current stimulation (tACS) can improve language skills in people with post-stroke aphasia. Participants will undergo real and sham tACS while performing language tests to measure effectiveness.See study design

What are the potential side effects?

Potential side effects of tACS may include mild discomfort or skin irritation at the electrode sites, headache, fatigue, or transient dizziness. These side effects are generally considered minimal.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have difficulty with speaking or understanding language.

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I had one stroke on the left side of my brain.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 5-10 minutes after a single session of active (alpha tacs) and sham (fake tacs).

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~5-10 minutes after a single session of active (alpha tacs) and sham (fake tacs).

This trial's timeline: 3 weeks for screening, Varies for treatment, and 5-10 minutes after a single session of active (alpha tacs) and sham (fake tacs). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Performance on the Blocked-Cyclic Naming (BCN) Task

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: real-tACSActive Control1 Intervention

The active stimulation will consist of an alternating current delivered in the alpha frequency band with a peak-to-peak intensity of 4 milliamps (mA) for 20 minutes. Participants will complete sentence completion and verb generation task during stimulation.

Group II: sham-tACSPlacebo Group1 Intervention

Sham stimulation involves the delivery of 60 seconds of the actual stimulation waveform ("ramp up") which is then gradually reduced to 0 milliamps (mA) ("ramp down"). Participants will complete sentence completion and verb generation task during stimulation.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor

2,005 Previous Clinical Trials

42,882,917 Total Patients Enrolled

11 Trials studying Aphasia

1,473 Patients Enrolled for Aphasia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this medical research open to participants aged sixty or above?

"This research study is accepting applicants aged 18 and beyond, up to a maximum of 85 years."

Answered by AI

Who can enlist in this trial within the parameters of qualification?

"To qualify for entry in this clinical trial, the patient must have aphasia and be between 18 to 85 years old. The goal is to acquire 120 participants before completion of recruitment."

Answered by AI

Are there any available slots for prospective participants in this research?

"According to the information supplied on clinicaltrials.gov, the recruitment phase for this medical trial has been concluded; it was first posted in November of 2023 and last updated in October of that same year. However, there are 1197 other trials currently accepting participants."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

tACS to Enhance Language Abilities

2024. "tACS to Enhance Language Abilities". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06092814.

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