Your session is about to expire
← Back to Search
Other
Cervical Sympathetic Block for Cerebral Vasospasm
N/A
Waitlist Available
Led By Anna Maria Bombardieri, MD, PhD
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Patients hospitalized in the ICU and developing cerebral vasospasm after aneurysmal subarachnoid hemorrhage
Patients aged 18 and over
Timeline
Screening 3 weeks
Treatment Varies
Follow Up duration of recovery in icu (1-2 weeks)
Awards & highlights
Study Summary
This trial will assess if a cervical sympathetic block can improve cerebral blood flow & neurological function in people with aneurysm-related brain issues.
Who is the study for?
This trial is for adults over 18 who are in the ICU with cerebral vasospasm following a brain aneurysm bleed. It's not suitable for those with advanced kidney disease.Check my eligibility
What is being tested?
The study tests whether a cervical sympathetic block, which is an injection near the neck to interrupt nerve signals, can improve blood flow in the brain and neurological recovery after a subarachnoid hemorrhage.See study design
What are the potential side effects?
Potential side effects of cervical sympathetic block may include soreness or bruising at the injection site, temporary difficulty swallowing, hoarseness, and less commonly, drooping eyelid or pupil constriction.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am in the ICU due to brain vessel spasms after a brain bleed from an aneurysm.
Select...
I am 18 years old or older.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ duration of recovery in icu (1-2 weeks)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~duration of recovery in icu (1-2 weeks)
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cerebral blood flow
Neurological function
Secondary outcome measures
Cerebral blood flow velocity
Trial Design
1Treatment groups
Experimental Treatment
Group I: Cervical sympathetic blockExperimental Treatment1 Intervention
Patients hospitalized in the ICU and developing clinical manifestations of cerebral vasospasm will undergo a computerized tomography (CT) angiography and a CT perfusion scan. If the vasospasm will be confirmed by the CT imaging, a cervical sympathetic nerve block under ultrasound guidance will be performed. The block consists in the deposition of local anesthetic at the cervical sympathetic ganglion that will be visualized with an ultrasound device. A periganglionar catheter will be left in place. A CT angiography and CT perfusion will be repeated to check the effect of the block on the brain vasculature after the block is done.
Patients will have a daily monitoring of their neurological function and of their cerebral blood flow with transcranial doppler in the ICU.
Find a Location
Who is running the clinical trial?
Stanford UniversityLead Sponsor
2,396 Previous Clinical Trials
17,341,545 Total Patients Enrolled
Anna Maria Bombardieri, MD, PhDPrincipal InvestigatorStanford University
1 Previous Clinical Trials
10 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is enrollment in this research study still available?
"Based on the information available through clinicaltrials.gov, this medical trial is no longer actively recruiting participants. Originally posted in July 27th 2023 and last updated October 2nd of that same year, there are 409 other trials with open recruitment at present time."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger