Aerobic Exercise for Ovary Cancer
This study is evaluating whether moderate exercise may improve quality of life, decrease distress, and improve biomarkers associated with prognosis in individuals with ovarian cancer.
See full descriptionAbout the trial for Ovary Cancer
Treatment Groups
This trial involves 2 different treatments. Aerobic Exercise is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Eligibility
This trial is for female patients aged 18 and older. There are 8 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Aerobic Exercise will improve 5 primary outcomes in patients with Ovary Cancer. Measurement will happen over the course of Baseline up to 24 weeks.
Patient Q & A Section
What is ovary cancer?
Ovary cancer is a fast developing, highly lethal neoplasm. Approximately 65% of ovarian cancer cases are of low to moderate aggressiveness. The diagnosis of ovary cancer is often made at a later stage with metastases throughout the peritoneal cavity, liver, and/or brain. Most patients develop metastatic disease and exhibit elevated serum CA125 levels with poor prognostic significance.
What causes ovary cancer?
The most plausible cause of OvCa is a combination of inherited gene mutations and/or gene dosage alterations, that occur in women of reproductive age; however, other potential environmental exposures seem to play a significant role in OvCa risk.
How many people get ovary cancer a year in the United States?
Approximately 865 cases of [ovarian cancer](https://www.withpower.com/clinical-trials/ovarian-cancer) are diagnosed a year in the US. A substantial portion of these cases will remain un-reported, as women usually fail to visit a doctor and do not report a cancer on their cancer screenings. If one adds in all unreported cases, the number of ovarian cancer cases diagnosed a year is more than 1,300. This is a significant number, requiring additional effort to determine the actual number of cases occurring each year. This is an important consideration in the prevention of ovarian cancer as it is a preventable disease.
What are the signs of ovary cancer?
Coughing, vomiting and vomiting blood and feeling very cold and shivering are common signs of primary ovarian cancer. Other signs may include loss of appetite, weight loss and swelling in the abdomen.
Can ovary cancer be cured?
Ovary cancer is typically diagnosed earlier than prostate cancer but is still curable. There are about 30,000 new instances of ovarian cancer in New Zealand every year.
What are common treatments for ovary cancer?
Most patients with ovarian cancer are initially treated with surgery. The role of chemotherapy in the treatment of ovarian cancer is still under review. Radiation therapy is often used for some indications, but it is not as effective as chemotherapy, unless very high doses are used.
What is aerobic exercise?
In the present investigation, aerobic exercise was found to improve the quality of life of ovarian cancer patients who have received chemotherapy or radiotherapy therapy. It is also helpful to achieve a good recovery rate. However, further studies with appropriate sample size are needed to further verify our findings.
Is aerobic exercise typically used in combination with any other treatments?
Aerobic exercise and a combination treatment regimen may be preferable in terms of disease-free survival in women with ovarian cancer. However, a large multicenter study is needed to confirm these findings.
Have there been other clinical trials involving aerobic exercise?
Although there is a little supporting evidence, aerobic exercise has been associated with overall mortality reduction, especially for breast, colorectal cancers. Further prospective and well-designed studies are needed to support the claims of the epidemiological evidence.
Is aerobic exercise safe for people?
Based on the available evidence, aerobic exercise training has no detrimental effects on general health. There is still more quality of evidence needed on this issue due to inconsistencies in the current findings and the lack of good quality clinical studies.
What is the primary cause of ovary cancer?
In a recent study, findings support a hypothesis that in utero exposure to pesticides (DDT (Dow Pesticide), etc.) is related to endocrine disruption, which in turn, may be related to endometrial cancer risk in later life.
Does ovary cancer run in families?
Findings from a recent study support that ovarian cancer penetrates into families. Moreover, they suggest that genetic predisposition may be part of the causal pathway.