Lifestyle Changes for Pancreatic Cancer Risk Reduction
(PANTHER-PIC Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment for reducing pancreatic cancer risk?
Research suggests that physical activity and lifestyle changes can help reduce the risk of pancreatic cancer by lowering body weight, improving insulin sensitivity (how well the body uses insulin), and decreasing inflammation. Studies have shown that consistent physical activity over time may slightly lower the risk of developing pancreatic cancer.12345
Is it safe for humans to participate in lifestyle changes like diet and exercise for reducing pancreatic cancer risk?
Research on diet and exercise interventions in pancreatic cancer patients shows that these lifestyle changes are generally safe, with studies focusing on adherence and adverse events during exercise programs. While the studies vary in design and outcomes, they do not report significant safety concerns for humans.25678
How does the treatment of lifestyle changes for pancreatic cancer risk reduction differ from other treatments?
This treatment focuses on modifying lifestyle factors like diet and physical activity to reduce the risk of pancreatic cancer, unlike traditional treatments such as surgery or chemotherapy, which are used after the disease has developed. By addressing modifiable risk factors like obesity and physical inactivity, this approach aims to prevent the disease before it starts.1291011
What is the purpose of this trial?
The purpose of this Study is to assist in implementing a practical, easy-to-adopt lifestyle intervention that optimizes patient outcomes and minimizes pancreatic ductal adenocarcinoma (PDAC) risk.
Research Team
Shaffer Mok, MD
Principal Investigator
Moffitt Cancer Center
Eligibility Criteria
This trial is for individuals at risk of pancreatic cancer, specifically PDAC. It's designed to see if lifestyle changes like increased physical activity and improved nutrition can help reduce their risk. Details on who exactly can join are not provided, but typically participants would need to meet certain health criteria.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Lifestyle Intervention
Participants engage in a lifestyle intervention involving 150 minutes/week of moderate to vigorous physical activity and nutritional counseling following a Mediterranean diet.
Follow-up
Participants are monitored for retention, adherence, and acceptability of lifestyle modifications.
Treatment Details
Interventions
- Nutrition
- Physical Activity
Find a Clinic Near You
Who Is Running the Clinical Trial?
H. Lee Moffitt Cancer Center and Research Institute
Lead Sponsor
Miles for Moffitt
Collaborator