Study Summary
This trial will help determine if dulaglutide can prevent high blood sugar levels in people without diabetes who are having surgery.
- Stress Hyperglycemia
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
4 Primary · 50 Secondary · Reporting Duration: Up to 3 months after discharge
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Continuous Glucose Monitoring
1 of 3
Dulaglutide
1 of 3
Placebo
1 of 3
Experimental Treatment
Non-Treatment Group
245 Total Participants · 3 Treatment Groups
Primary Treatment: Continuous glucose monitor (CGM), blinded · Has Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 45 - 80 · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
What is the upper cap of participants involved in this experiment?
"Affirmative. The information available at clinicaltrials.gov specifies that this medical experiment is actively enrolling individuals, which was first announced on July 29th 2021 and was last updated the same day. It seeks to recruit 245 members from two separate sites." - Anonymous Online Contributor
Who is qualified to partake in this medical experiment?
"This clinical trial requires 245 individuals aged 45 to 80 with hyperglycemia. Of particular note, the required criteria are: BMI ≥30 kg/m2 and no prior diagnosis of diabetes mellitus (DM), male or female participants between 45-80 years undergoing non-cardiac general or vascular surgery in Aim 1., and an additional requirement of either pre-diabetes by OGTT or HbA1c for those without known history of DM also participating in Aim 1." - Anonymous Online Contributor
What are the primary aims of this investigation?
"The primary aim of this trial, which is expected to be completed within two weeks (depending on hospital stay duration), is to measure the prevalence of stress hyperglycemia. Secondary indicators that will also be observed include number and percentage of transfers from ICU in SH patients, frequency of hypoglycaemia events under a glucose level below 40 mg/dL, as well as length of hospitalisation for those with or without SH." - Anonymous Online Contributor
Has the Continuous Glucose Monitor been granted blind approval by the FDA?
"Our team at Power has determined that the safety of Continuous Glucose Monitor (CGM) technology, when used in a blinded fashion, is highly reliable based on its Phase 4 status; this treatment option is already approved." - Anonymous Online Contributor
What medical reason is the Continuous Glucose Monitor (CGM) typically utilized for?
"The use of a Continuous glucose monitor (CGM) has been demonstrated to effectively manage type 2 diabetes mellitus, reduce cardiovascular risk factors, and adjust dietary habits." - Anonymous Online Contributor
Are there any available slots remaining in this clinical trial?
"Affirmative. Clinicaltrials.gov indicates that this investigation, which was inaugurated on July 29th 2021, is actively seeking out patients to join their team of 245 individuals from 2 different medical sites." - Anonymous Online Contributor
Is there a minimum age requirement for participation in the research study?
"This clinical trial requests applicants between the ages of 45 and 80. For those outside this age range, 4 separate studies are available for under 18s and over 65s respectively." - Anonymous Online Contributor