Study Summary
This trial will evaluate the impact of regular, professional non-surgical Intensive Periodontal Therapy (scaling and root planing and optimal oral hygiene with associated professional oral health behavior advice ), on oral health as well as whether such effects are associated with corresponding changes to biomarkers characterizing systemic health.
- Cardiovascular Disease
- Diabetes
Treatment Effectiveness
Effectiveness Progress
Study Objectives
3 Primary · 13 Secondary · Reporting Duration: Comparing T1 (day 90) and T4 (day 360)
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Control Group
1 of 2
Treatment Group
1 of 2
Active Control
Experimental Treatment
200 Total Participants · 2 Treatment Groups
Primary Treatment: Periodonal Treatment · No Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 8 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
In what contexts is Periodonal Treatment regularly utilized?
"As a general practice, periodontal treatment is utilized to eliminate bacteria and cure infections. Additionally, it can be applied to treat throat injuries and pressure sores." - Anonymous Online Contributor
What primary objectives are being sought through this research endeavor?
"This clinical trial will run for 360 days, with the primary objective of determining a relationship between changes in oral health and systemic effects (measured by Flow-mediated dilation). Secondary aims include assessing any shifts in Glycated hemoglobin levels among prediabetic or type 2 diabetic patients, gauging whether periodontal probing results have changed after treatment, and analysing patient beliefs surrounding periodontal disease through use of the Protective Motivation Theory questionnaire." - Anonymous Online Contributor
Is this research venture open to new participants?
"This medical trial is presently in search of participants, as evidenced by clinicaltrials.gov which indicates that this experiment was put on the site on September 28th 2021 and updated for last time on July 18th 2022." - Anonymous Online Contributor
Has the FDA certified Periodonal Treatment as a safe and effective treatment?
"There is ample evidence to suggest that Periodontal Treatment can be used safely, so Power's team gave it a score of 3." - Anonymous Online Contributor
How many participants are engaged with this clinical trial?
"Affirmative. Clinicaltrials.gov states that this clinical trial, which went public on September 28th 2021, is currently admitting enrollees. 200 people must be recruited from 2 diverse locations for the study to reach completion." - Anonymous Online Contributor