This trial is evaluating whether Point of care screening for HPR will improve 1 primary outcome and 3 secondary outcomes in patients with Peripheral Arterial Disease (PAD). Measurement will happen over the course of after study completion.
This trial requires 296 total participants across 2 different treatment groups
This trial involves 2 different treatments. Point Of Care Screening For HPR is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 3 and have had some early promising results.
"Although a clear cause is not universally recognised it seems clear that many common vascular risk factors are linked to an increased incidence and prevalence of peripheral arterial disease. The increased incidence of peripheral arterial disease seen in men with prior myocardial infarction is especially intriguing and the extent to which increased cardiovascular risk is due to shared genetic susceptibility or environmental influences needs to be determined." - Anonymous Online Contributor
"Peripheral arterial disease is a disorder of the small arteries and arterioles that are located above the knee in the limb. It is often a result of the buildup of plaque in the arteries that make up the lower extremities. There may also be a buildup of plaque in the arteries in the leg above the knee. Patients usually begin to feel symptoms of peripheral arterial disease as their legs becomes clogged.\n" - Anonymous Online Contributor
"About 7.9 million Americans are diagnosed with arterial disease of the lower limbs each year, and the risk of death among these patients is about 11 times greater than the general population." - Anonymous Online Contributor
"In symptomatic peripheral arterial disease, the treatment should be done according to existing evidence and experience, and to maximize the quality of life. The treatment of PAD is likely to have less effect on the survival of PAD patients than on delaying disease progression but improving quality of life." - Anonymous Online Contributor
"Signs of peripheral arterial disease include increased ankle to brachial ratio on pulse examination, bruit at the ankle during arterial phase of duplex ultrasound scanning." - Anonymous Online Contributor
"Most common treatment for claudication by primary healthcare providers is referral for PTA. More importantly, the common treatment for PAD is exercise, which may actually cause a change in the way claudication is viewed and treated by primary healthcare providers. Physicians should keep their treatments up-to-date and emphasize the role of exercise in treatment." - Anonymous Online Contributor
"Today, new treatment options for PAD are limited in terms of their efficacy and feasibility. However, there have been recent advances made in developing new therapies for the treatment of PAD and vascular disease in general. Research is still ongoing to further improve PAD-specific treatment options." - Anonymous Online Contributor
"Screening for hereditary hemorrhagic conditions is commonly performed in health systems with limited resources at points of care where there are no definitive diagnostic tests such as specialized laboratories. The performance of validated point-of-care tests such as HPB in an emergency setting as shown in this study can be highly effective in identifying individuals who require further diagnostic evaluation with testing that is not readily available." - Anonymous Online Contributor
"Data from a recent study, PAD was more common in white patients, had a history of smoking, and was more frequent in patients with diabetes without other risk factors for atherosclerosis, such as hypertension or hypercholesterolemia. No significant differences were observed for sex, age, family history of PAD, type of diabetes, level of microvascular surveillance, atherosclerotic risk factors, or prior cardiovascular surgery. The cause of PAD was found to be a combination of identifiable atherosclerotic risk factors, known aetiologies, and other undetermined causes." - Anonymous Online Contributor
"The use of the HPS in the clinic setting will decrease the number of CXRs performed and the radiation exposure received by patients. The decrease in CXRs performed will be clinically beneficial for patients and overall, the facility." - Anonymous Online Contributor
"In a recent study, findings we used a rigorous control sample and were able to control for important lifestyle and family characteristics that may influence PAD prevalence. There is no evidence in this study linking familial PAD with disease penetrance or with specific genetic risk variants." - Anonymous Online Contributor
"Among patients in need of POC testing on the grounds of PAD, the majority were tested, but several common side effects were observed. Patients' perceptions of test result disclosure, satisfaction with POC test performance and the overall experience of POC test utilization may be important considerations in clinical decision-making." - Anonymous Online Contributor