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Standard replacement therapy regimen for Cardiovascular Risk Reduction
Study Summary
This trial is testing different doses of estrogen to see which is most effective in reducing the risk of heart disease in women who have had their ovaries removed before age 46.
- Cardiovascular Risk Reduction
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
What overarching goals is this clinical trial attempting to achieve?
"The primary evaluation of this clinical trial, which occurs at Baseline, 6 months, and 12 months is to assess Change in Endothelial function. Additional objectives include gauging Change in Arterial tonometry (Arterial stiffness via high-fidelity pressure waveforms), assessing the index of baroreflex sensitivity (Colder pressor test immersing hand up to wrist in ice water) and measuring whole body and regional fat/fat-free mass (via Dual energy x-ray absorptiometry scans)."
How many participants are being invited to join this experiment?
"Affirmative. Information hosted on clinicaltrials.gov confirms that this medical research, which was initially posted on March 15th 2019, is actively recruiting individuals for participation. Sixty volunteers need to be enlisted from 1 trial location."
Are there any openings for participants in this research study at present?
"Indeed, clinicaltrials.gov reveals that this research is actively seeking participants as of October 17th 2022. Initially published on March 15th 2019, the trial requires 60 volunteers from a single medical facility."
Is the age eligibility for this trial limited to those under 30?
"To be included in this research, individuals must range between 21 and 45 years old. There are 32 studies for those under 18 and 389 trials catered towards seniors above 65."
Does the FDA currently recognize a Standard replacement therapy regimen?
"Taking into account the lack of prior clinical data demonstrating efficacy, Standard replacement therapy regimen has been assigned a rating of 2 on our safety scale."
For which clinical indications is the Standard replacement therapy regimen usually prescribed?
"Replacement therapy is the go-to course of action for those with amenorrhea, as well as individuals experiencing hypoestrogenism, vasomotor symptoms related to menopause and breast ailments."
Who has the potential to qualify for this medical research?
"Participants between the ages of 21 and 45 who are looking to reduce their cardiovascular risk can expect to be recruited for this trial. Approximately 60 people will be chosen in total."
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