This trial is evaluating whether Perflutren lipid microsphere will improve 1 primary outcome and 2 secondary outcomes in patients with Kidney Neoplasms. Measurement will happen over the course of (Baseline).
This trial requires 25 total participants across 1 different treatment group
This trial involves a single treatment. Perflutren Lipid Microsphere is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"All patients will have an increased risk of developing cancer in their kidney. Nephrectomy is a procedure that may be an option to help keep a kidney neoplasm from growing. Another option is a watch-and-wait policy as long as a person does not have a life-threatening or debilitating symptom. Kidney transplantation may be an option for those who will not tolerate a watch-and-wait policy. The signs of kidney neoplasms in children do not differ dramatically from the signs in adults." - Anonymous Online Contributor
"The cure of a renal tumor is a possibility if the tumor is surgically treated after neoadjuvant chemotherapy. However, cure rates are low and relapse may occur even if the main tumor is removed. Therefore, cure of kidney tumors is not recommended in the present clinical situation." - Anonymous Online Contributor
"These cases are most commonly treated by radical nephrectomy or nephron sparing surgery. The patient will undergo periodic scans for the detection of recurrent disease." - Anonymous Online Contributor
"There are more than 120,000 new cases of kidney cancer each year in the United States. Most tumors occur by the age of 55 and only 5% of them are diagnosed within the 5-year interval after the detection of a kidney mass." - Anonymous Online Contributor
"The most common and well-known kidney neoplasm is renal cell cancer, which is one of the most lethal forms of cancer. An estimated 30,000 new cases of kidney cancer will be diagnosed in the USA in 2011, accounting for 1.4% of all newly diagnosed cancers. It is a disease of the older patient population with an annual prevalence of 8.8/100,000." - Anonymous Online Contributor
"Individuals infected with parasites and those exposed to pesticides or solvents have a greater risk of kidney neoplasms. The link between infections and kidney neoplasms seems to be related to the immunodeficiency of the infected person and inflammation of the kidney tissue." - Anonymous Online Contributor
"This meta-analysis is the first meta-analysis to evaluate PUF versus PL MPS in the treatment of kidney cancer. PUF-LV did not demonstrate differences in efficacy in terms of QOL outcomes relative to PL MPS. Future studies should systematically evaluate the role of PL MPS in improving patient QOL." - Anonymous Online Contributor
"Findings from a recent study from clinical trials suggest that LDL-bound perflubron is highly specific for tumour imaging, and could potentially be used as a diagnostic parameter in patients with early-stage carcinomas or borderline lesions." - Anonymous Online Contributor
"In a recent study, findings of this study do not support the hypothesis that treatment with PFM compares to placebo in patients with advanced carcinoma of the pleural cavity." - Anonymous Online Contributor
"According to the results of this study, the odds of having kidney neoplasms are low, with no particular risk factors associated with the disease development." - Anonymous Online Contributor
"About half of kidney tumors are RCCs and more than half of the remaining tumors are renal cell carcinomas that are metastatic at time of diagnosis (i.e., they disseminated from the kidney). The prognosis of RCC is generally worse when it is not localized or diagnosed at an early stage. The prognosis in tumors of the other type, metastatic at the time of diagnosis, is significantly worse regardless of the nature of treatment, such as surgery." - Anonymous Online Contributor
"Although kidney neoplasms rarely lead to death before diagnosis, they may cause severe pain and compromise physical and mental well-being after diagnosis. Kidney neoplasms cause significant suffering for the patients before diagnosis. Furthermore, a high prevalence of renal tumors in patients with a previous history of kidney neoplasms suggests that neoplasms may be underdiagnosed." - Anonymous Online Contributor