Cognitive Behavioral Therapy for Insomnia

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DG
Overseen ByDaniel Gartenberg, PhD
Age: 65+
Sex: Any
Trial Phase: Phase 2
Sponsor: Proactive Life Inc
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This double blind randomized clinical trial on older independent-living healthy individuals with symptoms of insomnia will harness Cognitive Behavioral Therapy for Insomnia (CBT-I) and augment it with ambulatory data collection devices, personalized digital content, and smart sound and light cues (CBT-I +Internet of Things \[IoT\]+Artificial Intelligence \[AI\]). With this approach, the investigators aim to overcome many of the limitations that CBT-I in the clinic faces: the investigators can implement it in ambulatory settings while providing increased (remote) accessibility to therapy. The investigators will compare the CBT-I +IoT+AI to active controls that also integrate with smart phone devices, including SleepEZ, which is also based on CBT-I, and sleep hygiene education. These active controls will help determine whether CBT-I +IoT+AI is effective at treating insomnia based on the Insomnia Severity Index (ISI) (primary outcome), sleep metrics (secondary outcome), cognitive performance (secondary outcome), and additional outcomes like therapeutic adherence and other mental health assessments. Participants will be asked to track sleep with wearable and nearable devices, complete surveys, and complete cognitive assessments.

Who Is on the Research Team?

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Daniel Taylor, PhD

Principal Investigator

University of Arizona

Are You a Good Fit for This Trial?

This trial is for older, healthy adults living independently who have trouble sleeping. Participants should be experiencing symptoms of insomnia but not have other major health issues that could affect their sleep or cognitive function.

Inclusion Criteria

Has a residence with WIFI
Fluent English speaker and reader
Validated, abbreviated phone-based remote Montreal Cognitive Assessment (MoCA) testing score of ≥18
See 8 more

Exclusion Criteria

Illicit drug use in the past month except for marijuana
Diagnosed serious mental health disorder including psychosis, bipolar depression, severe major depression, moderate to high risk of suicide, dementia
I am currently in or have completed a therapy program for insomnia.
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What Are the Treatments Tested in This Trial?

Interventions

  • CBT-I-IoT-AI
  • SleepEZ CBTi
  • Sleep Hygiene IoT

Trial Overview

The study tests a high-tech version of Cognitive Behavioral Therapy for Insomnia (CBT-I) using smart devices and AI to see if it improves sleep better than standard CBT-I (SleepEZ) or just learning about good sleep habits. It measures how well participants sleep, their mental sharpness, and if they stick with the therapy.

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Active Control

Group I: CBT-I-IoT-AIExperimental Treatment1 Intervention
Group II: Sleep Hygiene + IoTActive Control1 Intervention
Group III: Sleep-EZ CBT-I Based SolutionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Proactive Life Inc

Lead Sponsor

Trials
1
Recruited
60+

National Institute on Aging (NIA)

Collaborator

Trials
1,841
Recruited
28,150,000+