Protein Supplement + Urolithin A for Muscle Atrophy
Trial Summary
What is the purpose of this trial?
There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain foods can help reduce these declines. Recent research suggests that Urolithin A, which is a natural compound that can be produced after eating pomegranates, nuts, and berries, improves muscle health. In this study, the investigators aim to investigate if a protein beverage (standard care during disuse) with or without Urolithin A can reduce or prevent the loss of muscle health while wearing a knee brace (muscle disuse).
Research Team
Stuart Phillips
Principal Investigator
McMaster University
Eligibility Criteria
This trial is for healthy, non-smoking men aged 18-30 with a BMI of 20-30 kg/m^2. Participants must not have orthopedic issues affecting the knee, gastrointestinal conditions, excessive alcohol use, or allergies to study ingredients. They can't be on certain medications or supplements that affect muscle health.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- Protein supplement (Other)
- Protein supplement with Urolithin A (Other)
Find a Clinic Near You
Who Is Running the Clinical Trial?
McMaster University
Lead Sponsor