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Social Stress Test for Social Anxiety (SSBI Trial)

N/A

Waitlist Available

Led By John D.E. Gabrieli, PhD

Research Sponsored by Massachusetts Institute of Technology

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 1

Awards & highlights

SSBI Trial Summary

This trial looks at how stress affects the brain, and whether it affects how we think and feel.

Who is the study for?

This trial is for healthy English-speaking adults aged 18-55 who can consent to participate. They must be right-handed, not pregnant, drug-free, and without significant mental health issues or severe medical conditions. Participants should not have used certain medications recently and must pass a social anxiety scale test.Check my eligibility

What is being tested?

The study is testing how experiencing social stress affects brain activity in healthy individuals. It uses the Trier Social Stress Test (TSST) followed by neuroimaging to observe changes in brain activation patterns.See study design

What are the potential side effects?

Since this trial involves a stress test and MRI scans, side effects may include temporary stress-related responses such as increased heart rate or anxiety during the TSST, and discomfort or claustrophobia during MRI scanning.

SSBI Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 1

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 1

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Differences in fMRI BOLD Response

SSBI Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Film + TSSTExperimental Treatment1 Intervention

Nature Film + Trier Social Stress Test (TSST)

Group II: Film Only (No-TSST)Active Control1 Intervention

Nature Film Only

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Trier Social Stress Test (TSST)

2020

N/A

~210

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Massachusetts Institute of TechnologyLead Sponsor

97 Previous Clinical Trials

12,729,937 Total Patients Enrolled

Massachusetts General HospitalOTHER

2,935 Previous Clinical Trials

13,198,591 Total Patients Enrolled

John D.E. Gabrieli, PhDPrincipal InvestigatorMassachusetts Institute of Technology

1 Previous Clinical Trials

50 Total Patients Enrolled

Media Library

Film + TSST Clinical Trial Eligibility Overview. Trial Name: NCT05591404 — N/A

Social Anxiety Research Study Groups: Film + TSST, Film Only (No-TSST)

Social Anxiety Clinical Trial 2023: Film + TSST Highlights & Side Effects. Trial Name: NCT05591404 — N/A

Film + TSST 2023 Treatment Timeline for Medical Study. Trial Name: NCT05591404 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor open to individuals of forty years or older?

"This research is open to adults aged between 18 and 55. Patients younger than 18 or over 65 can turn to the 4 clinical trials that cater specifically for them respectively."

Answered by AI

Is this investigation still recruiting participants?

"According to clinicaltrials.gov, this medical experiment is not currently enrolling patients; the trial was first posted on November 1st 2022 and last edited on October 19th 2022. Nevertheless, there are 6 other trials that are presently seeking candidates."

Answered by AI

Who can be considered eligible to join this research project?

"This research trial is seeking 50 participants, aged 18-55, who experience social stress. To be eligible for the study, candidates must meet several criteria including: willing to provide written consent in English; negative results on a pregnancy test (for females); no clinically significant mental health issues; low score (<30) on Liebowitz Social anxiety Scale; right-handedness; stable medication regimen of same dose and frequency within past 30 days."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Investigating the Effects of Social Stress on Brain Imaging

2023. "Investigating the Effects of Social Stress on Brain Imaging". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05591404.

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