Pecan vs Pretzel Snacks for Cognitive Impairment
What You Need to Know Before You Apply
What is the purpose of this trial?
This project will investigate whether daily snack consumption can improve memory, mood, and overall brain function in people with cognitive impairment. Sixty participants, aged 50 and older, with cognitive impairment, will be randomly assigned to eat snacks, either pecans or pretzels, for three months. Researchers will also study how snacks (pecans and pretzels) may influence the body, including changes in gut bacteria, blood markers of inflammation, and signals that connect the gut and the brain.
Who Is on the Research Team?
Chwan-Li (Leslie) Shen, PhD
Principal Investigator
Texas Tech University Health Sciences Center School of Medicine
Are You a Good Fit for This Trial?
This trial is for men and women over 50 with cognitive impairment, evidenced by specific questionnaire scores. They must have stable medication doses, consume less than two servings of nuts per week, and be open to random snack assignments.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants consume either pecans or pretzels daily for 3 months to assess effects on brain health and gut-brain axis
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Pecan snack
- Pretzel snack
Trial Overview
The study tests if daily snacks (pecans or pretzels) can improve memory, mood, and brain function in those with cognitive issues. It also examines the effects on gut health and inflammation over three months.
How Is the Trial Designed?
2
Treatment groups
Active Control
Placebo Group
2.0 oz pecans daily for 3 months
3.5 oz pretzel snack daily for 3 months
Find a Clinic Near You
Who Is Running the Clinical Trial?
Texas Tech University Health Sciences Center
Lead Sponsor
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