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Full treatment for Opioid Use Disorder

Q: What are the potential risks associated with undergoing a complete therapeutic regimen?

<p>Given the limited safety and efficacy data available for Full treatment, it has been rated a 1 on our scale. This corresponds to its Phase 1 trial status.</p>

Q: What is the current number of participants being recruited for this medical study?

<p>Indeed, as per clinicaltrials.gov data, this trial is actively seeking volunteers. The initiative was initially listed on December 4th, 2023 and underwent its latest revision on February 4th, 2024. A total of 24 participants are sought after from a single designated site.</p>

Phase 1

Recruiting

Led By Layton Matt, MD

Research Sponsored by Washington State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age greater than 18 years

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the investigators will capture clinical chart dose records at one month and three months from baseline to determine if change in methadone was sustained

Awards & highlights

Study Summary

This trial aims to study if hyperbaric oxygen therapy (HBOT) is effective in reducing signs and symptoms of opioid withdrawal when compared to a sham treatment. The study also wants to see if HB

Who is the study for?

This trial is for adults over 18 who are enrolled in a supervised opioid treatment program at the Spokane Regional Health District. Participants must be able to read, speak, and write English and provide written informed consent.Check my eligibility

What is being tested?

The study tests if hyperbaric oxygen therapy (HBOT) can help with physical and psychological symptoms of opioid withdrawal during methadone dose reduction compared to a sham treatment. It also examines HBOT's role in increasing success rates of tapering off opioids.See study design

What are the potential side effects?

Possible side effects of HBOT may include ear pressure changes, sinus pain, temporary vision changes, fatigue, headache or feeling lightheaded. These are generally mild and resolve after treatments.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am older than 18 years.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the investigators will capture clinical chart dose records at one month and three months from baseline to determine if change in methadone was sustained

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the investigators will capture clinical chart dose records at one month and three months from baseline to determine if change in methadone was sustained

This trial's timeline: 3 weeks for screening, Varies for treatment, and the investigators will capture clinical chart dose records at one month and three months from baseline to determine if change in methadone was sustained for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Adjective Rating Scale of Withdrawal (ARSW)

Secondary outcome measures

Change in Methadone dose

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Full treatmentExperimental Treatment1 Intervention

Participants are administered 100% oxygen in the HBOT chamber at 2.0 ATA

Group II: Partial treatmentPlacebo Group1 Intervention

Participants are administered 21% oxygen in the HBOT chamber at <1.3 ATA.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Washington State UniversityLead Sponsor

101 Previous Clinical Trials

56,690 Total Patients Enrolled

Layton Matt, MDPrincipal InvestigatorWashington State University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the potential risks associated with undergoing a complete therapeutic regimen?

"Given the limited safety and efficacy data available for Full treatment, it has been rated a 1 on our scale. This corresponds to its Phase 1 trial status."

Answered by AI

What is the current number of participants being recruited for this medical study?

"Indeed, as per clinicaltrials.gov data, this trial is actively seeking volunteers. The initiative was initially listed on December 4th, 2023 and underwent its latest revision on February 4th, 2024. A total of 24 participants are sought after from a single designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering

Marian Wilson 2023. "Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05924022.

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