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Participants with Acute Respiratory Infections (ARI) in Outpatient Setting for Acute Respiratory Infection (ARGOS Trial)

Phase < 1
Waitlist Available
Research Sponsored by Janssen Research & Development, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 months
Awards & highlights

ARGOS Trial Summary

This trial looks at how often three different viruses - RSV, influenza, and SARS-CoV-2 - cause respiratory infections in people at high risk for severe illness. It also looks at whether RSV is linked to hospitalization for respiratory illness.

Eligible Conditions
  • Acute Respiratory Infection

ARGOS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants with Relative Risk of Acute Respiratory Infections (ARI)- related Hospitalization in Participants Positive for RSV with Lower Respiratory Tract Disease (LRTD) or Without LRTD
Percentage of Participants Positive for Influenza Virus
Percentage of Participants Positive for Respiratory Syncytial Virus (RSV)
+1 more
Secondary outcome measures
Orthomyxoviridae
Severe Acute Respiratory Syndrome
Percentage of Participants Positive for Influenza Virus Reporting ARI-related Hospitalizations During the Study Period
+15 more

ARGOS Trial Design

1Treatment groups
Experimental Treatment
Group I: Participants with Acute Respiratory Infections (ARI) in Outpatient SettingExperimental Treatment1 Intervention
Participants presenting with ARIs in an outpatient setting who are at high risk of progressing to severe disease will be screened for viral respiratory pathogens (respiratory syncytial virus [RSV], Influenza, severe acute respiratory syndrome coronavirus 2 [SARS-COV-2]) by collecting a nasal swab. If a participant is positive for RSV and/or influenza virus and/or SARS-CoV-2 based on a study test or standard-of-care (SOC) polymerase chain reaction (PCR)-based test, the participant will be eligible for enrollment in the study in the home-based short-term and long-term follow-up phases.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Nasal Swab Sample
2021
Completed Early Phase 1
~240

Find a Location

Who is running the clinical trial?

Janssen Research & Development, LLCLead Sponsor
975 Previous Clinical Trials
6,384,074 Total Patients Enrolled
Janssen Research & Development, LLC Clinical TrialStudy DirectorJanssen Research & Development, LLC
745 Previous Clinical Trials
3,959,671 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What results is this clinical trial hoping to achieve?

"This trial is scheduled to span one day and aims to assess the prevalence of Influenza Virus. Additional goals include measuring relative risk of ARI-related hospitalization in participants that test positive for either Influenza or SARS-CoV-2 with/without Lower Respiratory Tract Disease (LRTD). LRTD refers to a new onset or worsening from chronic condition consisting of at least three symptoms, like coughing, breathlessness, phlegm production, etc. Furthermore, this study will also track percentage of those participating who presented complications during screening and were diagnosed with/without LRTD."

Answered by AI

Does this research offer any opportunities for participants?

"Clinicaltrials.gov indicates that recruitment is ongoing for this trial, which was first made available to the public on December 20th 2021 and most recently updated on November 22nd 2022."

Answered by AI

What is the cap on recruitment for this research?

"Yes, according to clinicaltrials.gov this trial is actively accepting applications from eligible candidates. The original posting date was December 20th 2021 and the most recent update occurred on November 22nd 2022. This medical study needs 2960 patients at 42 sites in order to be completed successfully."

Answered by AI

Are there numerous research centers in Canada conducting this experiment?

"This study has recruited patients from a wide variety of locations, such as Urgent Care Clinical Trials Fort Worth in Texas, Innovative Research of West Florida and Washington University School of Medicine based in Missouri. In total there are 42 sites participating."

Answered by AI
~70 spots leftby Apr 2025