N-acetyl cysteine for Itching

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Wright State Physicians, Fairborn, OHItching+1 MoreN-acetyl cysteine - Drug
Eligibility
18 - 40
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether the over-the-counter drug N-acetyl cysteine (NAC) can help reduce itching. The study will last for about 2 and a half months, and participants will take NAC or a placebo for a week before switching to the other option.

Eligible Conditions
  • Itching
  • Skin Disorder

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Study Objectives

4 Primary · 0 Secondary · Reporting Duration: 7 days

7 days
Change in itch level from baseline with NAC.
Change in itch level from baseline with placebo.
Change in pain level from baseline with NAC.
Pain

Trial Safety

Safety Progress

1 of 3

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Side Effects for

Treatment With N-Acetyl Cysteine
35%Pruritis
10%Nausea
This histogram enumerates side effects from a completed 2017 Phase 1 & 2 trial (NCT02206152) in the Treatment With N-Acetyl Cysteine ARM group. Side effects include: Pruritis with 35%, Nausea with 10%.

Trial Design

2 Treatment Groups

N-acetyl Cysteine then Placebo
1 of 2
Placebo then N-acetyl Cysteine
1 of 2

Experimental Treatment

20 Total Participants · 2 Treatment Groups

Primary Treatment: N-acetyl cysteine · Has Placebo Group · Phase < 1

N-acetyl Cysteine then PlaceboExperimental Group · 2 Interventions: N-acetyl cysteine, Placebo · Intervention Types: Drug, Drug
Placebo then N-acetyl CysteineExperimental Group · 2 Interventions: N-acetyl cysteine, Placebo · Intervention Types: Drug, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
N-acetyl cysteine
2016
Completed Phase 4
~780
Placebo
1995
Completed Phase 3
~2640

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 7 days

Who is running the clinical trial?

Wright State UniversityLead Sponsor
39 Previous Clinical Trials
55,007 Total Patients Enrolled
Craig Rohan, MDPrincipal InvestigatorWright State University
1 Previous Clinical Trials
24 Total Patients Enrolled

Eligibility Criteria

Age 18 - 40 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Both males and females can participate.
People with any skin color can participate.
You understand the procedures and potential risks of the study.
References

Frequently Asked Questions

How many volunteer participants are enrolled in this clinical trial?

"Affirmative. Data hosted on clinicaltrials.gov showcases that this medical trial, which was created on June 19th 2022 is conducting recruitment operations. The project necessitates the enrolment of 20 individuals from a single site." - Anonymous Online Contributor

Unverified Answer

Are there any openings for prospective participants in this research project?

"The trial is currently seeking participants, as indicated by the data on clinicaltrials.gov. This study was initially posted in June of 2022 and has since been updated in September of that same year." - Anonymous Online Contributor

Unverified Answer

Is there an age limit for patients involved in this research endeavor?

"This medical research trial is open to adults aged 18-40. For those under 18 and over 65, there are 16 and 61 alternative trials respectively." - Anonymous Online Contributor

Unverified Answer

What are the eligibility requirements for participating in this clinical research?

"Eligibility requirements for this medical trial mandate that potential participants be between 18 and 40 years old, with the symptom of pruritus. The study's investigators are seeking 20 patients in total." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

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