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What is Zolpimist
ZolpidemThe Generic name of this drug
Treatment SummaryZolpidem, also known as Ambien, is a medication used to treat insomnia. It helps people fall asleep faster and stay asleep longer, with minimal side effects when taken as directed. Zolpidem is available in both immediate acting and extended release forms. It is generally well-tolerated and has a low risk of addiction or tolerance. Furthermore, research suggests that Zolpidem can improve sleep quality for people with chronic insomnia and may even have the potential to help people in a vegetative state following brain injury.
Ambienis the brand name
Zolpimist Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ambien
Zolpidem
1993
361
Effectiveness
How Zolpimist Affects PatientsThis drug can make you feel sleepy, drowsy, dizzy, and less alert. For this reason, it is recommended that women take 5mg and men take either 5mg or 10mg of this drug just before bedtime, with at least 7-8 hours before you need to wake up. Taking this drug can cause memory problems, so be careful when driving a car or operating machinery the day after taking it. It has been shown to help people fall asleep faster and is thought to not cause withdrawal symptoms when taken in recommended doses. Higher doses of this drug have been linked to memory problems and sleepiness the next
How Zolpimist works in the bodyZolpidem is a hypnotic medication that works differently from drugs like benzodiazepines and barbiturates. It binds to a specific kind of receptor on the brain called the GABA-BZ receptor complex. This receptor is made up of several different parts, with the alpha subunit being the most important. Zolpidem specifically binds to the alpha 1, 2, and 3 subunits of the GABA receptor. These subunits are found in different parts of the brain, including the sensorimotor cortex, substantia nigra, and cerebellum. Zolpidem's binding to this specific
When to interrupt dosage
The recommended measure of Zolpimist is contingent upon the diagnosed condition. The magnitude of dosage fluctuates, as per the technique of delivery (e.g. Tablet, film coated - Oral or Tablet - Sublingual) outlined in the table hereunder.Condition
Dosage
Administration
Insomnia
, 6.25 mg, 12.5 mg, 10.0 mg, 5.0 mg, 3.5 mg, 1.75 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Spray, metered, Spray, metered - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Sublingual, Tablet - Sublingual, Tablet, extended release, Tablet, extended release - Oral, Kit, Kit - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual
Warnings
Zolpimist has one contraindication and should not be administered if you have any of the ailments indicated in the following table.Zolpimist ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Zolpidem may interact with Pulse Frequency
Common Zolpimist Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Zolpidem.
Azelastine
Major
Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Zolpidem.
Deutetrabenazine
Major
The risk or severity of sedation and somnolence can be increased when Zolpidem is combined with Deutetrabenazine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Zolpidem.
Zolpimist Toxicity & Overdose RiskThe toxic dose of zolpidem for male rats is 695mg/kg. Signs of an overdose include drowsiness, confusion, and shallow breathing, which can be fatal. Symptoms like those seen with other drugs when withdrawing may also occur. Long-term use in rats showed irregular menstrual cycles and prolonged time before pregnancy in females, but not a decrease in fertility. Zolpidem is considered a pregnancy category C drug and should only be used if the benefits outweigh the risks to the fetus. Breastfeeding mothers should be careful as some of the drug can pass into breastmilk.
Zolpimist Novel Uses: Which Conditions Have a Clinical Trial Featuring Zolpimist?
A total of 82 active trials are investigating the potential of Zolpimist to provide relief from Insomnia.Condition
Clinical Trials
Trial Phases
Insomnia
93 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1
Zolpimist Reviews: What are patients saying about Zolpimist?
5Patient Review
4/1/2011 I was able to get a full seven hours of sleep, which is something that I haven't been able to do in months! Definitely recommend this product to others who are struggling with insomnia.
5Patient Review
4/20/2011 This treatment is much faster-acting than pills.
5Patient Review
9/15/2011 I liked the taste of this spray and found that it worked very quickly. I was in a good mood within minutes, similar to how I feel after having a light beer.
5Patient Review
1/31/2012 Despite its bitter cherry taste, this medication works faster than Ambien or Temazepam. I've also used it in the middle of the night with success.
5Patient Review
3/23/2012 This product is great! You don't need to swallow a pill and it works very quickly.
5Patient Review
10/5/2012 Zolpimist has helped me get better sleep than anything else I've tried, like Ambien and Zolpidem. It's also really easy to use, which is great.
5Patient Review
12/9/2011 The safety bottle is a little inconvenient, but I understand the need for it. The product knocked me out completely; I was asleep before I realized it. As others have said, there were some funny side-effects, but nothing intolerable.
5Patient Review
7/6/2011 I was able to fall asleep so quickly, I didn't even have time to take my glasses off. This product is amazing and the only side effect I experienced was a brief period of giddiness.
5Patient Review
4/21/2011 This medication works very quickly.
5Patient Review
3/5/2012 This is, by far, the best product on the market for insomnia.
4.3Patient Review
4/13/2012 I appreciate that I don't feel high or out of control when taking this medication, given my history of substance abuse. The only downside is the lack of transparency about how much product is left in the bottle.
4.3Patient Review
1/11/2012 The bottle is difficult to open, but I understand why that might be necessary. The taste, however, is incredibly bitter and strong. It's hard to keep down even with chase it with water. If the medicine weren't more effective than pills, the taste would definitely be a dealbreaker for me!
1.3Patient Review
6/1/2017 No effects of sleepiness after 1 spray at all. Some effect after 2nd spray. Not worth It , will go back to tablet
1Patient Review
4/18/2012 This didn't work for me at all.
Patient Q&A Section about zolpimist
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is ZolpiMist prescription?
"Zolpimist is a prescription medicine used to treat the symptoms of Insomnia by helping people fall asleep and stay asleep. Zolpimist may be used alone or with other medications."
Answered by AI
Is ZolpiMist addictive?
"This medication may sometimes cause addiction, especially if you have a substance use disorder. Take this medication exactly as prescribed to lower the risk of addiction."
Answered by AI