Zolpimist

Insomnia

Treatment

0 Active Studies for Zolpimist

What is Zolpimist

Zolpidem

The Generic name of this drug

Treatment Summary

Zolpidem, also known as Ambien, is a medication used to treat insomnia. It helps people fall asleep faster and stay asleep longer, with minimal side effects when taken as directed. Zolpidem is available in both immediate acting and extended release forms. It is generally well-tolerated and has a low risk of addiction or tolerance. Furthermore, research suggests that Zolpidem can improve sleep quality for people with chronic insomnia and may even have the potential to help people in a vegetative state following brain injury.

Ambien

is the brand name

Zolpimist Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Ambien

Zolpidem

1993

361

Effectiveness

How Zolpimist Affects Patients

This drug can make you feel sleepy, drowsy, dizzy, and less alert. For this reason, it is recommended that women take 5mg and men take either 5mg or 10mg of this drug just before bedtime, with at least 7-8 hours before you need to wake up. Taking this drug can cause memory problems, so be careful when driving a car or operating machinery the day after taking it. It has been shown to help people fall asleep faster and is thought to not cause withdrawal symptoms when taken in recommended doses. Higher doses of this drug have been linked to memory problems and sleepiness the next

How Zolpimist works in the body

Zolpidem is a hypnotic medication that works differently from drugs like benzodiazepines and barbiturates. It binds to a specific kind of receptor on the brain called the GABA-BZ receptor complex. This receptor is made up of several different parts, with the alpha subunit being the most important. Zolpidem specifically binds to the alpha 1, 2, and 3 subunits of the GABA receptor. These subunits are found in different parts of the brain, including the sensorimotor cortex, substantia nigra, and cerebellum. Zolpidem's binding to this specific

When to interrupt dosage

The recommended measure of Zolpimist is contingent upon the diagnosed condition. The magnitude of dosage fluctuates, as per the technique of delivery (e.g. Tablet, film coated - Oral or Tablet - Sublingual) outlined in the table hereunder.

Condition

Dosage

Administration

Insomnia

, 6.25 mg, 12.5 mg, 10.0 mg, 5.0 mg, 3.5 mg, 1.75 mg

, Oral, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Spray, metered, Spray, metered - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Sublingual, Tablet - Sublingual, Tablet, extended release, Tablet, extended release - Oral, Kit, Kit - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Sublingual

Warnings

Zolpimist has one contraindication and should not be administered if you have any of the ailments indicated in the following table.

Zolpimist Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Zolpidem may interact with Pulse Frequency

There are 20 known major drug interactions with Zolpimist.

Common Zolpimist Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Zolpidem.

Azelastine

Major

Zolpidem may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Dacomitinib

Major

The metabolism of Dacomitinib can be decreased when combined with Zolpidem.

Deutetrabenazine

Major

The risk or severity of sedation and somnolence can be increased when Zolpidem is combined with Deutetrabenazine.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Zolpidem.

Zolpimist Toxicity & Overdose Risk

The toxic dose of zolpidem for male rats is 695mg/kg. Signs of an overdose include drowsiness, confusion, and shallow breathing, which can be fatal. Symptoms like those seen with other drugs when withdrawing may also occur. Long-term use in rats showed irregular menstrual cycles and prolonged time before pregnancy in females, but not a decrease in fertility. Zolpidem is considered a pregnancy category C drug and should only be used if the benefits outweigh the risks to the fetus. Breastfeeding mothers should be careful as some of the drug can pass into breastmilk.

image of a doctor in a lab doing drug, clinical research

Zolpimist Novel Uses: Which Conditions Have a Clinical Trial Featuring Zolpimist?

A total of 82 active trials are investigating the potential of Zolpimist to provide relief from Insomnia.

Condition

Clinical Trials

Trial Phases

Insomnia

0 Actively Recruiting

Zolpimist Reviews: What are patients saying about Zolpimist?

5

Patient Review

4/1/2011

Zolpimist for Difficulty Falling Asleep

I was able to get a full seven hours of sleep, which is something that I haven't been able to do in months! Definitely recommend this product to others who are struggling with insomnia.

5

Patient Review

4/20/2011

Zolpimist for Difficulty Falling Asleep

This treatment is much faster-acting than pills.

5

Patient Review

9/15/2011

Zolpimist for Difficulty Falling Asleep

I liked the taste of this spray and found that it worked very quickly. I was in a good mood within minutes, similar to how I feel after having a light beer.

5

Patient Review

1/31/2012

Zolpimist for Difficulty Falling Asleep

Despite its bitter cherry taste, this medication works faster than Ambien or Temazepam. I've also used it in the middle of the night with success.

5

Patient Review

3/23/2012

Zolpimist for Difficulty Falling Asleep

This product is great! You don't need to swallow a pill and it works very quickly.

5

Patient Review

10/5/2012

Zolpimist for Difficulty Falling Asleep

Zolpimist has helped me get better sleep than anything else I've tried, like Ambien and Zolpidem. It's also really easy to use, which is great.

5

Patient Review

12/9/2011

Zolpimist for Difficulty Falling Asleep

The safety bottle is a little inconvenient, but I understand the need for it. The product knocked me out completely; I was asleep before I realized it. As others have said, there were some funny side-effects, but nothing intolerable.

5

Patient Review

7/6/2011

Zolpimist for Difficulty Falling Asleep

I was able to fall asleep so quickly, I didn't even have time to take my glasses off. This product is amazing and the only side effect I experienced was a brief period of giddiness.

5

Patient Review

4/21/2011

Zolpimist for Difficulty Falling Asleep

This medication works very quickly.

5

Patient Review

3/5/2012

Zolpimist for Difficulty Falling Asleep

This is, by far, the best product on the market for insomnia.

4.3

Patient Review

4/13/2012

Zolpimist for Difficulty Falling Asleep

I appreciate that I don't feel high or out of control when taking this medication, given my history of substance abuse. The only downside is the lack of transparency about how much product is left in the bottle.

4.3

Patient Review

1/11/2012

Zolpimist for Difficulty Falling Asleep

The bottle is difficult to open, but I understand why that might be necessary. The taste, however, is incredibly bitter and strong. It's hard to keep down even with chase it with water. If the medicine weren't more effective than pills, the taste would definitely be a dealbreaker for me!

1.3

Patient Review

6/1/2017

Zolpimist for Difficulty Falling Asleep

No effects of sleepiness after 1 spray at all. Some effect after 2nd spray. Not worth It , will go back to tablet

1

Patient Review

4/18/2012

Zolpimist for Difficulty Falling Asleep

This didn't work for me at all.

Patient Q&A Section about zolpimist

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is ZolpiMist used for?

"ZolpiMist contains the active ingredient zolpidem, which is a type of medicine called a non-benzodiazepine.

ZolpiMist is used to treat insomnia in adults. It contains zolpidem, a non-benzodiazepine, which is a type of medicine that helps you sleep."

Answered by AI

How long does ZolpiMist last?

"Zolpimist is indicated for the treatment of insomnia characterized by difficulties with sleep initiation. Zolpidem tartrate has been shown to decrease sleep latency for up to 35 days in controlled clinical studies."

Answered by AI

Is ZolpiMist prescription?

"Zolpimist is a prescription medicine used to treat the symptoms of Insomnia by helping people fall asleep and stay asleep. Zolpimist may be used alone or with other medications."

Answered by AI

Is ZolpiMist addictive?

"This medication may sometimes cause addiction, especially if you have a substance use disorder. Take this medication exactly as prescribed to lower the risk of addiction."

Answered by AI