Study Summary
This trial is investigating why bariatric surgery is more effective than diet-induced weight loss in reducing obesity, with a focus on brain mechanisms. CSF neuropeptide, hormone, and protein levels will be measured to determine if some of the changes that are expected to occur after diet-induced weight loss do not occur after bariatric surgery.
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
2 Primary · 2 Secondary · Reporting Duration: Up to 12 months
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Roux-en-Y Gastric Bypass Surgery
1 of 3
Sleeve Gastrectomy Surgery
1 of 3
Very Low Calorie Diet
1 of 3
Active Control
48 Total Participants · 3 Treatment Groups
Primary Treatment: Roux-en-Y Gastric Bypass Surgery · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 65 · All Participants · 2 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| New York | 100.0% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| Columbia University Medical Center | 100.0% |
What portion of applicants met pre-screening criteria?
| Met criteria | 100.0% |
Why did patients apply to this trial?
- "I suffer from sleep apnea and knees,back, ankle arthritis along as well as ASTHMA SO I MUST start LOOSING 60 lbs.asap."
How many prior treatments have patients received?
| 2 | 100.0% |
How responsive is this trial?
Most responsive sites:
- Columbia University Medical Center: < 24 hours
Average response time
- < 1 Day
Typically responds via
| 100.0% | |
Frequently Asked Questions
Do I satisfy all the criteria necessary to partake in this research?
"This trial is seeking 48 individuals with obesity between the age of majority and seniority. The Body Mass Index (BMI) must be in-between 35 to 55, otherwise they will not meet the requirements for inclusion into this study." - Anonymous Online Contributor
Is the study currently recruiting participants?
"Clinicaltrials.gov confirms that this medical study is still recruiting, with the initial posting occurring on October 20th 2020 and last update logged as March 21st 2022." - Anonymous Online Contributor
How many people are eligible to participate in this experiment?
"Yes, according to clinicaltrials.gov the research is actively enrolling participants. This experiment was initially announced on October 20th 2020 and has been recently updated March 21st 2022. There are 48 spaces available at one location for this trial." - Anonymous Online Contributor
Does this trial include individuals aged 80 and over?
"The age range for applicants to this trial is 18-65. Nevertheless, there are 202 trials available for those below the lower limit and 596 experiments open to people above the upper boundary." - Anonymous Online Contributor