Axillary lymphadenetomy alone for Lymphedema

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Stanford Cancer Institute, San Francisco, CA
Lymphedema+2 More
Axillary lymphadenetomy alone - Procedure
Eligibility
18+
Female
What conditions do you have?
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Study Summary

Lymphedema is a chronic, progressive, and debilitating condition that occurs with disruption or obstruction of the lymphatic system, which commonly occurs a result of breast cancer therapy. The purpose of this study is to determine if the use of a low risk lymphatic reconstruction procedure at the time of axillary lymph node dissection will reduce the risk of developing lymphedema. Additionally, to determine if this procedure improves objective outcomes of lymphedema and patient quality of life

Eligible Conditions

  • Lymphedema
  • Breast

Treatment Effectiveness

Study Objectives

5 Primary · 0 Secondary · Reporting Duration: 2 yr

2 yr
Bioiimpedance spectroscopy
Limb Volume
Lymphatic flow pattern of whole limb
Quality of life
Skin thickness measurements

Trial Safety

Trial Design

2 Treatment Groups

Group B
1 of 2
Group A
1 of 2
Active Control
Experimental Treatment

80 Total Participants · 2 Treatment Groups

Primary Treatment: Axillary lymphadenetomy alone · No Placebo Group · N/A

Group A
Procedure
Experimental Group · 1 Intervention: Axillary lymphadenetomy alone · Intervention Types: Procedure
Group B
Procedure
ActiveComparator Group · 1 Intervention: axillary lymphadenectomy with immediate lymphatic reconstruction (LYMPHA) · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 2 yr
Closest Location: Stanford Cancer Institute · San Francisco, CA
Photo of San Francisco 1Photo of San Francisco 2Photo of San Francisco 3
2017First Recorded Clinical Trial
1 TrialsResearching Lymphedema
43 CompletedClinical Trials

Who is running the clinical trial?

Stanford UniversityLead Sponsor
2,130 Previous Clinical Trials
35,668,830 Total Patients Enrolled
11 Trials studying Lymphedema
6,430 Patients Enrolled for Lymphedema

Eligibility Criteria

Age 18+ · Female Participants · 7 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are undergoing breast cancer related axillary lymphadenectomy.
Axillary lymph node biopsy results must be either negative or positive.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.