Beta-Glucan for Melanoma

University of Louisville, Louisville, KY
Melanoma+1 More ConditionsBeta-Glucan - DietarySupplement
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will study how beta-glucan, a type of dietary fiber, affects the immune system in people with melanoma.

Eligible Conditions
  • Melanoma Stage III
  • Metastatic Melanoma

Treatment Effectiveness

Phase-Based Effectiveness

1 of 3
N/A

Similar Trials

1
Group I Beta-Hydroxy-Butyrate
1
Quadrivalent Inactivated Influenza Vaccine
1
Pembrolizumab

Study Objectives

6 Primary · 0 Secondary · Reporting Duration: Blood for analysis will be drawn at baseline (Day 0), 3 weeks post pembrolizumab treatment, and 3 weeks post pembrolizumab plus oral beta-glucan

Week 3
Changes in absolute number of intracellular cytokine expression markers
Changes in absolute number of lymphocyte cell surface expression markers
Changes in fluorescent intensity of intracellular cytokine expression markers
Body Weight Changes
Changes in the mean fluorescent intensity of lymphocyte cell surface expression markers
Week 3
Changes in percent of lymphocyte cell surface expression markers

Trial Safety

Phase-Based Safety

1 of 3

Similar Trials

1
Group I Beta-Hydroxy-Butyrate
1
Quadrivalent Inactivated Influenza Vaccine
1
Pembrolizumab

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Treatment
1 of 1

Experimental Treatment

30 Total Participants · 1 Treatment Group

Primary Treatment: Beta-Glucan · No Placebo Group · N/A

Treatment
DietarySupplement
Experimental Group · 1 Intervention: Beta-Glucan · Intervention Types: DietarySupplement
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Beta-Glucan
2018
N/A
~60

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: blood for analysis will be drawn at baseline (day 0), 3 weeks post pembrolizumab treatment, and 3 weeks post pembrolizumab plus oral beta-glucan

Who is running the clinical trial?

Kelly McMastersLead Sponsor
Kelly M McMasters, MDPrincipal InvestigatorUniversity of Louisville

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are able to swallow pills.
People from any racial or ethnic background can participate in this study.
References

Frequently Asked Questions

How many participants are being monitored during this research endeavor?

"Affirmative. Information available on clinicaltrials.gov asserts that this medical trial, first posted back in November 2020, is currently recruiting participants at one site with a need for 30 patients." - Anonymous Online Contributor

Unverified Answer

Is recruitment currently underway for this experiment?

"Affirmative. Clinicaltrials.gov reveals that this trial was initially posted on November 3rd 2020, and is still actively recruiting participants with edits last made on January 7th 2022. 30 people need to be recruited at a single site in order for the study to continue." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top