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What is Velivet
DesogestrelThe Generic name of this drug
Treatment SummaryDesogestrel is a synthetic hormone used to prevent pregnancy. It is a type of progestin, a form of progesterone, derived from plant steroids. Desogestrel is only available in combination with ethinyl estradiol in the US, and was first developed in 1972 and approved by the FDA in 1992.
Desogenis the brand name
Velivet Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Desogen
Desogestrel
1992
68
Effectiveness
How Velivet Affects PatientsDesogestrel is a medication that affects fertility, menstrual cycle, and metabolism. It mainly works by stopping ovulation in 97% of cycles, and can have a Pearl failure rate of 0.17 per 100 women-years. Desogestrel can also cause the endometrium to change, and certain hormones to be suppressed. Although it can increase the risk of venous thromboembolism due to increased blood coagulation, it does not significantly impact the level of total cholesterol.
How Velivet works in the bodyDesogestrel works by binding to the progesterone receptor in cells, activating a transcription factor that modifies mRNA synthesis. The active metabolite of desogestrel, [etonogestrel], has a high progestational activity with low androgenic activity.
When to interrupt dosage
The measure of Velivet is contingent upon the diagnosed state, such as Birth Control, Nursing Women and Hormonal Contraception. The quantity of dosage is dependent upon the mode of delivery (e.g. Kit or Kit; Tablet - Oral) highlighted in the table beneath.Condition
Dosage
Administration
Hormonal Contraception
, 0.15 mg, 0.1 mg, 0.125 mg, 0.375 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Birth Control
, 0.15 mg, 0.1 mg, 0.125 mg, 0.375 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Warnings
Velivet has twenty-five contraindications, and its use should be avoided when confronted with any of the afflictions listed in the following table.Velivet ContraindicationsCondition
Risk Level
Notes
Cerebrovascular Diseases
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Liver Cancer
Do Not Combine
Endometrial Carcinoma
Do Not Combine
Thromboembolism
Do Not Combine
Thromboembolism
Do Not Combine
Major Surgery
Do Not Combine
benign hepatic adenoma
Do Not Combine
Breast Cancer
Do Not Combine
hepatocellular disease
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast
Do Not Combine
Type 2 Diabetes
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Thrombophlebitis
Do Not Combine
Thrombophilia
Do Not Combine
Diastolic blood pressure
Do Not Combine
> 160 mm Hg systolic blood pressure
Do Not Combine
Jaundice, Obstructive
Do Not Combine
history of deep vein thrombophlebitis
Do Not Combine
Icterus
Do Not Combine
focal neurological symptoms
Do Not Combine
valvular heart disease with complications
Do Not Combine
estrogen-dependent neoplasia
Do Not Combine
Common Velivet Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be increased when combined with Desogestrel.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Desogestrel.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Desogestrel.
Enasidenib
Major
The metabolism of Enasidenib can be increased when combined with Desogestrel.
Etoposide
Major
The metabolism of Etoposide can be increased when combined with Desogestrel.
Velivet Toxicity & Overdose RiskTaking too much desogestrel can cause strong hormonal effects, but is not considered to be severely toxic. The highest dose of desogestrel that is toxic to rats is 2000 mg/kg. Reports of desogestrel overdose have not described serious effects, only nausea and irregular bleeding. Studies have not found a link between desogestrel and increased risk of breast cancer, but some reports suggest an increased risk of cervical cell changes. However, this has not been conclusively proven.
Velivet Novel Uses: Which Conditions Have a Clinical Trial Featuring Velivet?
38 active studies are underway to ascertain the potential of Velivet in providing Nursing Women, Birth Control and Hormonal Contraception for treatment of certain disorders.Condition
Clinical Trials
Trial Phases
Birth Control
31 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Hormonal Contraception
0 Actively Recruiting
Velivet Reviews: What are patients saying about Velivet?
5Patient Review
10/25/2011 I was on Velivet for four years and never had any problems with veins in my legs. However, after reading some studies, I realize that this could be a side effect of the pill. I don't think they are as safe as they say they are.
5Patient Review
6/25/2012 I've had a great experience with this birth control. No problems whatsoever. I would definitely recommend it to anyone who is looking for an effective form of contraception.
4.7Patient Review
4/29/2018 I switched to this pill from caziant tablets two months ago. I haven't experienced any negative side effects, except for some breast pain before my period. The only downside is that my sex drive has completely disappeared.
4.7Patient Review
1/26/2017 I've been using this pill for a while now with great results. No weight gain, no change in mood (aside from the normal day-to-day stuff), and no real side effects that I can tell.
4.3Patient Review
11/13/2015 Overall, I really liked this pill. It had minimal side effects and my period was very light and short. However, I discontinued use of it as it severely decreased my sex drive.
4.3Patient Review
5/14/2020 I've been using this pill for acne treatment for the past four years, and it's been working well in tandem with a topical medication. I'm now of age to use it as contraception, and I haven't had any issues so far. Additionally, it regulates my periods and makes them shorter—which is great. The only notable side effects are mood swings that vary from month to month.
4.3Patient Review
1/5/2012 I grew a cup size from using this treatment, my acne cleared up, though there was some initial water retention.
4Patient Review
10/20/2008 I was previously on Othro-tricyclen but switched to this generic brand. So far, it's been working just as well for me. The only downside is that I've been experiencing breakthrough bleeding for about a week now; however, my doctor assured me this is normal and should subside soon.
3.7Patient Review
12/17/2012 I have been on this pill for 8 months. I gained weight, have no sex drive, and spot almost daily constantly. I hate this pill.
3.3Patient Review
7/8/2014 I took this brand of birth control for ten months. I experienced a significant weight gain, an increase in breast size, loss of sex drive, and daily headaches. While it was effective as contraception, the side effects were not worth it.
3Patient Review
2/18/2010 I've been on this medication for a while now. I generally don't have any issues, except for the occasional headache during the last week of each pack (which could also be from my period). My only real concern is that once I stop taking the pill, I'll be able to get pregnant.
3Patient Review
11/27/2007Patient Q&A Section about velivet
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What kind of birth control is Velivet?
"The Velivet birth control pill is a combination of female hormones that prevent ovulation. It also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus."
Answered by AI
Does Velivet cause weight gain?
"Some women report gaining weight while taking Velivet, while others report only a minimal decrease in appetite. There is a slight risk that you might gain weight when taking any oral contraceptive."
Answered by AI
Does Velivet have estrogen?
"This contraceptive medication contains a progestin and an estrogen to prevent pregnancy."
Answered by AI
Is Velivet a good birth control?
"Velivet has a 50/50 chance of working as a birth control according to reviewers."
Answered by AI