Norpace Cr

Ventricular Arrhythmia
1 FDA approval
4 Active Studies for Norpace Cr

What is Norpace Cr

DisopyramideThe Generic name of this drug
Treatment SummaryProcainamide is a medication used to treat irregular heartbeats. It works by stabilizing the electrical signals in the heart, similar to the drug guanidine. It also has properties that help with muscle spasms and numbness.
Norpaceis the brand name
image of different drug pills on a surface
Norpace Cr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?

Approved as Treatment by the FDA

Disopyramide, otherwise known as Norpace, is approved by the FDA for 1 uses which include Ventricular Arrhythmia .
Ventricular Arrhythmia
Helps manage Ventricular Arrhythmia


How Norpace Cr Affects PatientsDisopyramide is a drug used to treat serious heart rhythm problems. It helps to make the heart beat slower and more regularly. Disopyramide will also make areas of the heart's electrical system that control the heart rate longer, but does not have a significant effect on the other electrical pathways of the heart. However, it will cause some of the pathways to take longer to send signals.
How Norpace Cr works in the bodyDisopyramide is a type of drug used to treat irregular heart beats. It works by slowing down the electrical signals that cause your heart to beat. This drug has been shown to reduce the speed of diastolic depolarization and action potential duration in animal studies, as well as reduce the difference in refractoriness between damaged and healthy parts of the heart. Disopyramide does not affect the alpha- or beta-adrenergic receptors.

When to interrupt dosage

The prescribed amount of Norpace Cr is contingent upon the determined condition. The quantity of dosage is contingent upon the method of administration (e.g. Tablet, extended release - Oral or Oral) delineated in the table underneath.
Ventricular Arrhythmia
100.0 mg, , 150.0 mg, 250.0 mg
Tablet, extended release - Oral, Oral, Capsule, extended release, , Capsule, gelatin coated - Oral, Capsule, gelatin coated, Tablet, extended release, Capsule, extended release - Oral, Capsule - Oral, Capsule


Norpace Cr Contraindications
Risk Level
Prolonged QT interval
Do Not Combine
third degree AV block
Do Not Combine
Shock, Cardiogenic
Do Not Combine
There are 20 known major drug interactions with Norpace Cr.
Common Norpace Cr Drug Interactions
Drug Name
Risk Level
Disopyramide may increase the bradycardic activities of Acebutolol.
The risk or severity of adverse effects can be increased when Disopyramide is combined with Aclidinium.
Disopyramide may increase the bradycardic activities of Alprenolol.
Disopyramide may increase the bradycardic activities of Anisodamine.
Disopyramide may increase the bradycardic activities of Arotinolol.
Norpace Cr Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats has been found to be 580mg/kg.
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Norpace Cr Novel Uses: Which Conditions Have a Clinical Trial Featuring Norpace Cr?

At present, 4 active clinical trials are being conducted to assess the potential of Norpace Cr in managing Ventricular Arrhythmia.
Clinical Trials
Trial Phases
Ventricular Arrhythmia
3 Actively Recruiting
Not Applicable

Norpace Cr Reviews: What are patients saying about Norpace Cr?

5Patient Review
Norpace Cr for Atrial Fibrillation Electrically Shocked to Normal Rhythm
5Patient Review
Norpace Cr for Prevention of Recurrent Atrial Fibrillation
I'm glad this fourth medication I tried finally worked for my atrial fibrillation. I did have to be monitored in the hospital, but it was worth it to find a treatment that actually worked and didn't cause other issues like the Multaq I was on previously.
4.7Patient Review
Norpace Cr for Heart Ventricle Rhythm Problem
4.3Patient Review
Norpace Cr for Prevention of Recurrent Atrial Fibrillation
This treatment helps me stay in a normal heart rhythm, unless my potassium levels drop below 4.0.
3Patient Review
Norpace Cr for Heart Ventricle Rhythm Problem
I take this medication along with Coreg twice a day. I haven't had any problems as long as I stick to the name brand; however, when I tried the generic version, I experienced breakthrough irregularity.
1.7Patient Review
Norpace Cr for Heart Ventricle Rhythm Problem
My husband felt much better before taking this medication and told the doctor he would rather stop taking it because of the severe side effects. These included insomnia, a dry mouth and throat, constipation, and general discomfort. We stopped the medication immediately and found a different drug.
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Patient Q&A Section about norpace cr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class of drug is Norpace?

"Class Ia antiarrhythmic drugs work on the sodium channels in the heart. Disopyramide is one of these drugs. Other Class Ia antiarrhythmic drugs include procainamide and quinidine."

Answered by AI

Is Norpace CR available?

"The two strengths are available in a box of 30.

Pfizer has two strengths of Norpace CR 100 mg and 150 mg capsules available in a box of 30."

Answered by AI

What is Norpace CR used for?

"This medication is used to treat ventricular tachycardia, an irregular heartbeat that could be fatal. Disopyramide is an anti-arrhythmic drug that restores normal heart rhythm and maintains a regular, steady heartbeat."

Answered by AI

What is the difference between Norpace and Norpace CR?

"Norpace is a drug made of two isomers, d- and l-. It is not chemically related to other antiarrhythmic drugs. Norpace CR (controlled-release) capsules are designed to release disopyramide gradually and consistently."

Answered by AI

Clinical Trials for Norpace Cr