Norpace Cr

Ventricular Arrhythmia

Treatment

1 FDA approval

5 Active Studies for Norpace Cr

Treatment for

Ventricular Arrhythmia

What is Norpace Cr

DisopyramideThe Generic name of this drug

Treatment SummaryProcainamide is a medication used to treat irregular heartbeats. It works by stabilizing the electrical signals in the heart, similar to the drug guanidine. It also has properties that help with muscle spasms and numbness.

Norpaceis the brand name

image of different drug pills on a surface

Norpace Cr Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Norpace

Disopyramide

1977

Approved as Treatment by the FDA

Disopyramide, otherwise known as Norpace, is approved by the FDA for 1 uses which include Ventricular Arrhythmia .

Ventricular Arrhythmia

Helps manage Ventricular Arrhythmia

Effectiveness

How Norpace Cr Affects PatientsDisopyramide is a drug used to treat serious heart rhythm problems. It helps to make the heart beat slower and more regularly. Disopyramide will also make areas of the heart's electrical system that control the heart rate longer, but does not have a significant effect on the other electrical pathways of the heart. However, it will cause some of the pathways to take longer to send signals.

How Norpace Cr works in the bodyDisopyramide is a type of drug used to treat irregular heart beats. It works by slowing down the electrical signals that cause your heart to beat. This drug has been shown to reduce the speed of diastolic depolarization and action potential duration in animal studies, as well as reduce the difference in refractoriness between damaged and healthy parts of the heart. Disopyramide does not affect the alpha- or beta-adrenergic receptors.

When to interrupt dosage

The prescribed amount of Norpace Cr is contingent upon the determined condition. The quantity of dosage is contingent upon the method of administration (e.g. Tablet, extended release - Oral or Oral) delineated in the table underneath.

Condition

Dosage

Administration

Ventricular Arrhythmia

, 100.0 mg, 150.0 mg, 250.0 mg

, Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Tablet, extended release, Tablet, extended release - Oral, Capsule, extended release, Capsule, extended release - Oral

Warnings

Norpace Cr Contraindications

Condition

Risk Level

Notes

Prolonged QT interval

Do Not Combine

Shock, Cardiogenic

Do Not Combine

Atrioventricular Block

Do Not Combine

There are 20 known major drug interactions with Norpace Cr.

Common Norpace Cr Drug Interactions

Drug Name

Risk Level

Description

Acebutolol

Major

Disopyramide may increase the bradycardic activities of Acebutolol.

Aclidinium

Major

The risk or severity of adverse effects can be increased when Disopyramide is combined with Aclidinium.

Alprenolol

Major

Disopyramide may increase the bradycardic activities of Alprenolol.

Anisodamine

Major

Disopyramide may increase the bradycardic activities of Anisodamine.

Arotinolol

Major

Disopyramide may increase the bradycardic activities of Arotinolol.

Norpace Cr Toxicity & Overdose RiskThe lowest toxic dose of the drug in rats has been found to be 580mg/kg.

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Norpace Cr Novel Uses: Which Conditions Have a Clinical Trial Featuring Norpace Cr?

At present, 4 active clinical trials are being conducted to assess the potential of Norpace Cr in managing Ventricular Arrhythmia.

Condition

Clinical Trials

Trial Phases

Ventricular Arrhythmia

5 Actively Recruiting

Not Applicable, Phase 3, Phase 4

Norpace Cr Reviews: What are patients saying about Norpace Cr?

5Patient Review

8/17/2009

Norpace Cr for Atrial Fibrillation Electrically Shocked to Normal Rhythm

NO COMMENT

5Patient Review

10/3/2011

Norpace Cr for Prevention of Recurrent Atrial Fibrillation

I'm glad this fourth medication I tried finally worked for my atrial fibrillation. I did have to be monitored in the hospital, but it was worth it to find a treatment that actually worked and didn't cause other issues like the Multaq I was on previously.

4.7Patient Review

7/5/2009

Norpace Cr for Heart Ventricle Rhythm Problem

4.3Patient Review

11/10/2010

Norpace Cr for Prevention of Recurrent Atrial Fibrillation

This treatment helps me stay in a normal heart rhythm, unless my potassium levels drop below 4.0.

3Patient Review

12/19/2009

Norpace Cr for Heart Ventricle Rhythm Problem

I take this medication along with Coreg twice a day. I haven't had any problems as long as I stick to the name brand; however, when I tried the generic version, I experienced breakthrough irregularity.

View All Reviews

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Patient Q&A Section about norpace cr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class of drug is Norpace?

"Class Ia antiarrhythmic drugs work on the sodium channels in the heart. Disopyramide is one of these drugs. Other Class Ia antiarrhythmic drugs include procainamide and quinidine."

Answered by AI

Is Norpace CR available?

"The two strengths are available in a box of 30.

Pfizer has two strengths of Norpace CR 100 mg and 150 mg capsules available in a box of 30."

Answered by AI

What is Norpace CR used for?

"This medication is used to treat ventricular tachycardia, an irregular heartbeat that could be fatal. Disopyramide is an anti-arrhythmic drug that restores normal heart rhythm and maintains a regular, steady heartbeat."

Answered by AI

What is the difference between Norpace and Norpace CR?

"Norpace is a drug made of two isomers, d- and l-. It is not chemically related to other antiarrhythmic drugs. Norpace CR (controlled-release) capsules are designed to release disopyramide gradually and consistently."

Answered by AI

Clinical Trials for Norpace Cr

Have you considered Norpace Cr clinical trials? We made a collection of clinical trials featuring Norpace Cr, we think they might fit your search criteria.