Naphazoline Hydrochloride

Eye Pain, Photophobia, Iritis + 21 more
Treatment
9 Active Studies for Naphazoline Hydrochloride

What is Naphazoline Hydrochloride

NaphazolineThe Generic name of this drug
Treatment SummaryNaphazoline is a drug used to quickly reduce nasal or eye congestion. It is found in many over-the-counter eye drops and nasal sprays. Naphazoline was developed in 1942 as a nasal medication to treat congestion.
AK-Conis the brand name
image of different drug pills on a surface
Naphazoline Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
AK-Con
Naphazoline
1974
43

Effectiveness

How Naphazoline Hydrochloride Affects PatientsNaphazoline is a drug that helps to reduce congestion in the nose or eyes by narrowing the small blood vessels at the site of administration.
How Naphazoline Hydrochloride works in the bodyNaphazoline is a medication used to decrease congestion. It works by stimulating alpha-adrenergic receptors on the walls of small arteries, causing them to constrict and reduce inflammation. It also stimulates beta-adrenergic receptors, which can cause rebound vasodilation once the alpha-adrenergic stimulation has ended. After long-term use, if naphazoline is suddenly stopped, it can cause rhinitis medicamentosa due to a decrease in norepinephrine production caused by a negative feedback loop.

When to interrupt dosage

The measure of Naphazoline Hydrochloride is contingent upon the perceived affliction, including Eye Pain, Sinusitis and tetracycline. The measure of dosage is affected by the mode of delivery (e.g. Solution / drops or Liquid - Ophthalmic) specified in the table beneath.
Condition
Dosage
Administration
Allergic Rhinitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Allergy to Tree Pollen
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
tetracycline
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Dermatitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Otitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Allergic Conjunctivitis (AC)
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Conjunctivitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Eye Pain
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Photophobia
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Iritis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Dry Eye Syndromes
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Dacryocystitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Pink Eye
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Sinusitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Blepharoconjunctivitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Eye
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
ocular bacterial infections
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
ocular vasoconstriction therapy
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Conjunctivitis, Bacterial
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic
Conjunctivitis
, 0.25 mg/mL, 0.2675 mg/mL, 0.00012 mg/mL, 0.12 mg/mL, 0.3 mg/mL, 0.1 mg/mL, 1.0 mg/mL, 0.5 mg/mL, 0.2 mg/mL, 0.00027 mL/mL, 0.01 mL/mL, 0.0125 mL/mL, 0.00015 mg/mL, 0.21 mL/mL, 0.0625 mL/mL, 0.0025 mg/mL, 0.012 %, 0.1 %, 1.0 mg, 0.051 %, 0.02675 %, 0.05 %, 0.025 %, 5.0 mg/mL, 0.03 %, 1.12 mg/mL, 0.00012 mg/mg, 0.00025 mg/mg, 0.27 mg/mL, 0.0625 mg/mL, 0.012 mg/mL, 0.01 %, 0.00376 mg/mg
, Solution / drops, Ophthalmic, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid, Nasal, Liquid - Nasal, Spray - Nasal, Spray, Suspension / drops, Suspension / drops - Nasal, Topical, Solution / drops - Topical, Solution / drops - Nasal, Gel - Ophthalmic

Warnings

Naphazoline Hydrochloride has one contraindication, and it ought not to be taken for the conditions in the following table.Naphazoline Hydrochloride Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Naphazoline may interact with Pulse Frequency
There are 20 known major drug interactions with Naphazoline Hydrochloride.
Common Naphazoline Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Iobenguane
Major
Naphazoline can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Naphazoline is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
5-methoxy-N,N-dimethyltryptamine
Minor
The risk or severity of hypertension can be increased when Naphazoline is combined with 5-methoxy-N,N-dimethyltryptamine.
Abediterol
Minor
The risk or severity of hypertension can be increased when Naphazoline is combined with Abediterol.
Aceclofenac
Minor
The risk or severity of hypertension can be increased when Naphazoline is combined with Aceclofenac.
Naphazoline Hydrochloride Toxicity & Overdose RiskTaking too much naphazoline can cause serious effects, such as decreased alertness, low body temperature, slowed heartbeat, and even death. This is especially true for children under 6. People who use naphazoline for long periods of time may experience a stuffy nose when they stop taking the medicine. It is not known whether naphazoline is safe or effective in children under 12, or in elderly patients. It is also not known if naphazoline is safe during pregnancy, while breastfeeding, or if it affects fertility.
image of a doctor in a lab doing drug, clinical research

Naphazoline Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Naphazoline Hydrochloride?

57 active studies are investigating the potential of Naphazoline Hydrochloride to mitigate Sinusitis, Dermatitis and Allergic Rhinitis.
Condition
Clinical Trials
Trial Phases
Conjunctivitis
0 Actively Recruiting
Photophobia
2 Actively Recruiting
Not Applicable
Sinusitis
2 Actively Recruiting
Not Applicable
Eye
0 Actively Recruiting
Dry Eye Syndromes
0 Actively Recruiting
Iritis
0 Actively Recruiting
Rhinitis, Allergic
0 Actively Recruiting
Lacrimal Duct Obstruction
0 Actively Recruiting
Eye Pain
0 Actively Recruiting
Conjunctivitis, Bacterial
0 Actively Recruiting
tetracycline
0 Actively Recruiting
Blepharoconjunctivitis
0 Actively Recruiting
ocular vasoconstriction therapy
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Pink Eye
0 Actively Recruiting
Otitis
0 Actively Recruiting
Dermatitis
0 Actively Recruiting
Dacryocystitis
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Lacrimation
0 Actively Recruiting

Naphazoline Hydrochloride Reviews: What are patients saying about Naphazoline Hydrochloride?

5Patient Review
7/5/2017
Naphazoline Hydrochloride for Red Eyes
The active ingredient in Clear Eyes, naphazoline ophthalmic, is much more effective than other over-the-counter treatments like Visine. I've used it for a variety of issues – pink eye, sore eyes from staring at a computer all day, allergies, and even just puffy eyes – and it's always worked great.
3.7Patient Review
9/19/2010
Naphazoline Hydrochloride for Red Eyes
My right eye was red and irritated for seven weeks before I found this treatment. The over-the-counter allergy drop really did the trick, better than the prescription medications my doctor gave me (which also came with some nasty possible side effects).
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about naphazoline hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does Naphazoline hydrochloride do?

"This medication is used to relieve redness in the eyes due to minor irritations. It is available in the form of a solution and can be prescribed by a doctor."

Answered by AI

What drug class is naphazoline?

"Naphazoline is a drug that is used to help with congestion. It is in a class of drugs known as sympathomimetic amines. This drug works by narrowing the blood vessels in the eye, which helps to reduce the amount of congestion."

Answered by AI

Is Naphazoline hydrochloride safe for eyes?

"Do not use naphazoline ophthalmic if you have narrow-angle glaucoma. If you experience ongoing or worsening eye redness, eye pain, vision changes, severe dizziness, headache, buzzing in your ears, or shortness of breath, stop using naphazoline ophthalmic and call your doctor."

Answered by AI

Is naphazoline an antihistamine?

"Naphazoline and pheniramine are a decongestant and antihistamine, respectively. They are both used in the eyes to relieve itching and redness caused by pollen, ragweed, grass, animal hair, and dander. These medicines may have other uses as well; you should ask your health care provider or pharmacist if you have any questions."

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Clinical Trials for Naphazoline Hydrochloride

Have you considered Naphazoline Hydrochloride clinical trials? We made a collection of clinical trials featuring Naphazoline Hydrochloride, we think they might fit your search criteria.Go to Trials
Image of Vancouver General Hospital in Vancouver, Canada.

In-Clinic Endoscopic Polypectomy for Nasal Polyps

18+
All Sexes
Vancouver, Canada
Chronic rhinosinusitis, also called chronic sinusitis, is a very common life-long disease affecting over 5% of the Canadian population. Its symptoms, including daily facial pain and headache, an inability to breath through the nose and complete smell loss, regularly impair one's ability to work and to enjoy and participate in daily activities. The annual cost of chronic sinusitis to Canada is estimated at $1.3 billion while the government pays an estimated $860 million yearly for chronic sinusitis treatment. Chronic sinusitis with polyps, the most common type of chronic sinusitis, is usually treated with a combination of medications and surgery. Until now, surgical treatment has only been performed in the operating room, at a cost of about $3500 per procedure. But, recent studies have shown that a new procedure, "in-clinic polyp removal", can provide an improvement in patient symptoms to levels equal to those for sinus surgery performed in a hospital operating room. Moreover, in clinic polyp removal has additional advantages including a shorter procedure recovery time, a significantly lower cost to the health care system (about one-tenth the cost or $450), and a shorter wait time for treatment. With the proposed pragmatic trial, the investigators will determine whether the in clinic polyp removal procedure is as good as sinus surgery in the operating room at controlling patient symptoms of chronic sinusitis. The investigators will also determine the cost and health-benefits for a patient, the healthcare system and for society of in clinic polyp removal in comparison to sinus surgery done in a hospital operating room. The investigators will then know if this new treatment, in clinic polyp removal, can replace sinus surgery as the standard of care for these patients.
Recruiting
Has No Placebo
Vancouver General Hospital (+4 Sites)Shaun Kilty, MDMedtronic
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