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Healthy Control subjects for Light Sensitivity

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Light Sensitivity+2 MorePupillography - Device
Eligibility
18 - 80
All Sexes
What conditions do you have?
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Study Summary

This trial will test a new way of diagnosing and treating light sensitivity and headache by measuring a person's facial features, pupil responses, retinal electrical responses, and autonomic nerve responses to light.

Eligible Conditions
  • Light Sensitivity
  • Migraine
  • Traumatic Brain Injury

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 1 Day

1 Day
Correlation of facial responses to light sensitivity
Correlation of objective biological marker of light sensitivity to macula (structure found in the back of the eye).
Correlation of objective biological marker of light sensitivity to optic nerve structures
Difference in objective biological markers of light sensitivity between light sensitive and normal subjects

Trial Safety

Safety Progress

1 of 3

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2
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2
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Trial Design

5 Treatment Groups

Healthy Control subjects
1 of 5
Migraine patients with photosensitivity
1 of 5
TBI Patients without photosensitivity
1 of 5
Migraine patients without photosensitivity
1 of 5
TBI patients with photosensitivity
1 of 5

Active Control

120 Total Participants · 5 Treatment Groups

Primary Treatment: Healthy Control subjects · No Placebo Group · N/A

Healthy Control subjectsActiveComparator Group · 5 Interventions: Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device, Videography, Electrophysiology · Intervention Types: Device, Device, Device, Device, Device
Migraine patients with photosensitivityActiveComparator Group · 5 Interventions: Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device, Videography, Electrophysiology · Intervention Types: Device, Device, Device, Device, Device
TBI Patients without photosensitivityActiveComparator Group · 5 Interventions: Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device, Videography, Electrophysiology · Intervention Types: Device, Device, Device, Device, Device
Migraine patients without photosensitivityActiveComparator Group · 5 Interventions: Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device, Videography, Electrophysiology · Intervention Types: Device, Device, Device, Device, Device
TBI patients with photosensitivityActiveComparator Group · 5 Interventions: Pupillography, Ocular Coherence Tomography (OCT), Wrist-watch sensor device, Videography, Electrophysiology · Intervention Types: Device, Device, Device, Device, Device

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 1 day

Who is running the clinical trial?

Randy KardonLead Sponsor
2 Previous Clinical Trials
1,000 Total Patients Enrolled

Eligibility Criteria

Age 18 - 80 · All Participants · 2 Total Inclusion Criteria

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References

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