Cytomel

Hypothyroidism, Hyperthyroidism, euthyroid Goitre + 6 more
Treatment
7 FDA approvals
20 Active Studies for Cytomel

What is Cytomel

LiothyronineThe Generic name of this drug
Treatment SummaryLiothyronine is a thyroid hormone that is produced naturally by the thyroid gland. It is four times more powerful than its chemical relative, thyroxine. Liothyronine can be produced artificially, and King Pharmaceuticals developed this product and it was approved by the FDA in 1956. It is used to treat hypothyroidism and other thyroid-related conditions.
Cytomelis the brand name
image of different drug pills on a surface
Cytomel Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cytomel
Liothyronine
1956
94

Approved as Treatment by the FDA

Liothyronine, commonly known as Cytomel, is approved by the FDA for 7 uses like Hyperthyroidism and Hypothyroidism .
Hyperthyroidism
Hypothyroidism
Helps manage Hypothyroidism
euthyroid Goitre
Helps manage euthyroid Goitre
Hypothyroidism
Helps manage Hypothyroidism
suppression test
Thyroid Gland
Hyperthyroidism

Effectiveness

How Cytomel Affects PatientsLiothyronine is a more powerful and faster-acting hormone replacement than levothyroxine, but it does not last as long. Treatment with liothyronine needs to be closely monitored, as fast correction of thyroid hormones can be risky and cause heart failure. After taking liothyronine, effects will be felt in a few hours and reach their peak after two to three days. Liothyronine will increase the amount of T3 hormone in the body, but has no effect on the amount of T4 hormone.
How Cytomel works in the bodyLiothyronine helps the body to produce the thyroid hormones it needs to function. It does this by binding to receptors in the DNA and controlling the process of transcription and protein synthesis. This helps to increase energy levels, accelerate cell growth and metabolism, and aid in the development of the nervous system. It also improves carbohydrate and protein metabolism.

When to interrupt dosage

The measure of Cytomel is contingent upon the diagnosed state, such as suppression test, Thyroid Gland and Comatose. The amount of dosage is contingent upon the system of delivery (e.g. Intravenous or Oral) noted in the table below.
Condition
Dosage
Administration
Hypothyroidism
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
myxedema pre-coma
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
suppression test
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
Thyroid Gland
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
Hyperthyroidism
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
Thyroid Cancer
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
supplemental or replacement therapy
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
euthyroid Goitre
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical
Comatose
, 0.025 mg, 0.005 mg, 0.05 mg, 0.01 mg/mL, 0.009 mg, 0.0045 mg, 0.0135 mg, 0.00225 mg, 0.018 mg, 0.0031 mg, 0.00625 mg, 0.0375 mg, 0.02 mg, 0.0125 mg, 0.027 mg
, Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, Injection - Intravenous, Topical, Tablet - Topical

Warnings

Cytomel Contraindications
Condition
Risk Level
Notes
Adrenal Insufficiency
Do Not Combine
Thyrotoxicosis
Do Not Combine
There are 20 known major drug interactions with Cytomel.
Common Cytomel Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Liothyronine may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetaminophen
Minor
Liothyronine may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Aclidinium
Minor
Liothyronine may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Liothyronine may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Adrenalone
Minor
Liothyronine may increase the vasoconstricting activities of Adrenalone.
Cytomel Toxicity & Overdose RiskThe most toxic dose of liothyronine found in rats is higher than 4540mg/kg. If someone overdoses on liothyronine, they may present with symptoms of hyperthyroidism, confusion, disorientation, cerebral embolism, seizure, shock, coma, or death. These effects can occur immediately or days after the overdose. To reduce the effects of the overdose, the dose of liothyronine should be lowered and supportive treatment provided. There have been no reports studying the cancer-causing or mutation-causing effects of liothyronine or its effects on fertility.
image of a doctor in a lab doing drug, clinical research

Cytomel Novel Uses: Which Conditions Have a Clinical Trial Featuring Cytomel?

45 active studies are currently assessing the potential of Cytomel to alleviate Hyperthyroidism, myxedema pre-coma and as a suppression test.
Condition
Clinical Trials
Trial Phases
Thyroid Cancer
37 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3
Comatose
0 Actively Recruiting
Thyroid Gland
0 Actively Recruiting
myxedema pre-coma
0 Actively Recruiting
suppression test
0 Actively Recruiting
Hyperthyroidism
0 Actively Recruiting
Hypothyroidism
5 Actively Recruiting
Phase 2, Phase 4, Phase 3, Not Applicable
euthyroid Goitre
0 Actively Recruiting
supplemental or replacement therapy
0 Actively Recruiting

Cytomel Reviews: What are patients saying about Cytomel?

5Patient Review
3/12/2014
Cytomel for Thyroid Cancer
I was really struggling before I started this medication. I couldn't focus at all and my skin felt like it was crawling. Thankfully, my primary care physician found that my T3 levels were low and put me on Cytomel. It worked wonders within just a few days.
5Patient Review
10/5/2014
Cytomel for T3 Suppression for Thyroid Function Test
I'm feeling great since I started taking cytomel. My doctor first prescribed 10mcg for 1 month, and then increased it to 25mcg after my T3 levels remained low at 71. I've lost the belly fat and my energy level is back to normal!!!! Love it!!!
5Patient Review
1/16/2014
Cytomel for Additional Treatment for Thyroid Cancer
I had a pretty tough time after my thyroid cancer diagnosis and treatment, but this medication has really helped me regain my energy and positivity.
5Patient Review
7/3/2022
Cytomel for Additional Medications to Treat Depression
Cytomel (37.5 mcg) was prescribed by my psychiatrist as an additional medication to help with my depression. It helped very quickly, even with some tolerable side effects.
5Patient Review
6/21/2018
Cytomel for Serious Decrease in Thyroid Function
For more than 10 years, I took the wrong thyroid medication (just synthroid). With Citomel, I finally found something that worked for me. Taking 150 mcg of synthroid and 12.5 of Cytomel has been a game-changer.
View All Reviews
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Patient Q&A Section about cytomel

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Cytomel good for weight loss?

"Using Cytomel for weight loss can cause you to lose weight, but it is not recommended as it can have other side effects."

Answered by AI

What is Cytomel used for?

"Liothyronine is a medication used to treat an underactive thyroid. It provides the thyroid hormone which is normally produced by the thyroid gland. Liothyronine is a man-made form of thyroid hormone."

Answered by AI

What are the most common side effects of Cytomel?

", sweating;, and increased urination

Some symptoms of hyperthyroidism include having trouble breathing, feeling irritable, having muscle weakness, increased appetite, sweating, and increased urination."

Answered by AI

Is Cytomel the same as levothyroxine?

"What are two medications that can replace thyroid hormones when your levels are low?

Synthroid and Cytomel"

Answered by AI

Clinical Trials for Cytomel

Have you considered Cytomel clinical trials? We made a collection of clinical trials featuring Cytomel, we think they might fit your search criteria.
Have you considered Cytomel clinical trials? We made a collection of clinical trials featuring Cytomel, we think they might fit your search criteria.
Have you considered Cytomel clinical trials? We made a collection of clinical trials featuring Cytomel, we think they might fit your search criteria.
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