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What is Banzel
RufinamideThe Generic name of this drug
Treatment SummaryRufinamide is a drug used to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. It works by controlling the abnormal electrical activity in the brain that leads to seizures. Clinical studies have shown that it is effective in treating partial seizures.
Banzelis the brand name
Banzel Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Banzel
Rufinamide
2008
21
Approved as Treatment by the FDA
Rufinamide, also known as Banzel, is approved by the FDA for 1 uses such as Lennox Gastaut Syndrome (LGS) .Lennox Gastaut Syndrome (LGS)
Used in combination with other therapies
Effectiveness
How Banzel Affects PatientsAt high doses, this drug prevents the production of glutamate by blocking the activity of a certain type of brain receptor (mGluR5).
How Banzel works in the bodyRufinamide is a medication used to treat epilepsy. It works by making it harder for electric signals to spread through the brain, which helps to stop seizures from happening. It does this by making voltage-gated sodium channels stay inactive for longer, which helps to stabilize the brain's membranes.
When to interrupt dosage
The prescribed measure of Banzel is contingent upon the recognized condition. The amount of dosage also depends on the technique of delivery outlined in the table beneath.Condition
Dosage
Administration
Lennox Gastaut Syndrome (LGS)
, 200.0 mg, 400.0 mg, 40.0 mg/mL, 100.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Tablet, Tablet - Oral
Warnings
Banzel has one restriction. It should not be administered when enduring the conditions presented in the following table.Banzel ContraindicationsCondition
Risk Level
Notes
familial short QT syndrome
Do Not Combine
Common Banzel Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Rufinamide.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Rufinamide.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Rufinamide.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Rufinamide.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Rufinamide.
Banzel Toxicity & Overdose RiskCommon side effects of this drug include headache, dizziness, tiredness, drowsiness, and nausea.
Banzel Novel Uses: Which Conditions Have a Clinical Trial Featuring Banzel?
Currently, 4 active trials are examining the utility of Banzel for treatment of Lennox Gastaut Syndrome (LGS).Condition
Clinical Trials
Trial Phases
Lennox Gastaut Syndrome (LGS)
3 Actively Recruiting
Phase 2, Phase 3
Banzel Reviews: What are patients saying about Banzel?
5Patient Review
9/29/2014 I didn't think this medication was working well at first, but when the doctor tried reducing my dosage I realized just how much it was helping me.
5Patient Review
10/7/2014 This is by far the best medication I have taken.
4.7Patient Review
2/1/2011 This treatment has been really helpful for me. It's made a big difference in my life.
4.3Patient Review
2/17/2014 This medication has been incredibly helpful, reducing my seizure frequency from 8 a day to just 4 or 6. The only downside is the price tag; it's quite expensive at $2400 per month.
3.7Patient Review
8/17/2010 My daughter was having tonic seizures every 5 minutes, despite also taking dilantil, felbatol, keppra, and klonopin. Banzel was added around March 2010, and by August 2010 we'd increased the dosage to 1600mg per day. The effect was amazing, but getting there was tough – she vomited a lot. Now as long as we feed her before she takes the meds, she's fine. She's 30 years old and has been disabled since birth due to uncontrolled seizures. This drug seems to be working for her.
3.7Patient Review
4/26/2011 This medication has helped my son to some degree, but he is still experiencing drop seizures.
3.7Patient Review
8/24/2009 I liked this treatment, but it's hard to say how much of the positive effects were due to Banzel and how much were due to the VNS device I got around the same time.
2.3Patient Review
9/23/2009 I started this medication six months ago at a low dose which I increased pretty rapidly over the next six weeks. At the same time, I was also decreasing another seizure medication. However, before I could get to the recommended dosage, I started gagging and trying to vomit.
1Patient Review
7/20/2009 Unfortunately, this new medication has caused my son to have more seizures.
Patient Q&A Section about banzel
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the generic for BANZEL?
"The generic version of Rufinamide (Banzel) is available and may be cheaper compared to the brand version."
Answered by AI
Can you overdose on BANZEL?
"If you take too much Banzel, you may have an overdose. Overdose symptoms may include confusion, drowsiness, and seizures. If you think you may have overdosed on Banzel, call your doctor or poison control center right away."
Answered by AI
What is BANZEL used for?
"Banzel is a prescription medication approved for treating seizures associated with Lennox-Gastaut Syndrome in patients aged one year and older."
Answered by AI
What is BANZEL made of?
"Banzel contains rufinamide, an active drug that belongs to a class of medications called antiepileptic drugs (AEDs). A class of medications is a group of drugs that work in the same way. Banzel is available as 200-milligram (mg) and 400-mg tablets."
Answered by AI