Anesthesia Clinical Trials
Here are the 6 most popular medical studies for anesthesia
Behavioural Intervention
Self-directed and simulation-assisted training +1 More for Medical Education
The purpose of this study is to determine whether a self-directed and simulation-based lung ultrasound (LUS) and focused cardiac ultrasound (FCU) curriculum is efficacious on anesthesia trainees' image acquisition skills and diagnostic acumen. The investigators hypothesize that a self-directed and ultrasound-assisted LUS and FCU curriculum that includes video lectures, online teaching modules, an ultrasound simulator, and self-directed hands-on sessions on critically ill mechanically ventilated patients is effective in training novice ultrasonographers to obtain good quality images, to correctly interpret them, and to support clinical decision-making in critically ill patients. Trainees will be randomized to fully supervised FCU hands-on sessions on healthy models and critically ill mechanically ventilated patients (control group - traditional apprenticeship model) or to a completely self-directed and simulation-based approach (intervention group). To assess if this new self-directed and simulation-based ultrasound curriculum leads to adequate acquisition of competences (adequate image acquisition and interpretation) in novice ultrasonographers, trainees will have to perform a focused lung and cardiac assessment on a critically ill mechanically ventilated patient.
Procedure
Sevoflurane/oxygen/air/nitrous oxide for High Blood Pressure
It is controversial whether or not patients whose Renin Angiotensin System is blocked for the treatment of hypertension suffer increased risk when undergoing surgery and anaesthesia. The investigators wish to test the hypothesis: Blockade of the Renin Angiotensin System causes altered dose response under general anaesthesia in a dose dependant manner. The investigators wish to look for altered responses across the usual anaesthetic dosing range as measured by blood pressure and heart responses.
Local Anesthetic
Ropivacaine 0.75% for Shoulder Pain
Interscalene block (ISB) consistently demonstrates superior pain relief after shoulder surgery. However, patients can experience complications such as blurred vision, hoarseness and shortness of breath with the standard volumes of local anesthetic used in contemporary practice. Patients with respiratory diseases are precluded because of the potential effects on respiration. However, they are then exposed to the risks of general anesthesia and opioid medications which can also have detrimental effects on respiration. Ultrasound guided ISB can reduce the local anesthetic volume required to produce anesthesia for shoulder surgery; this may reduce the complications from ISB to allow patients previously unable to benefit to have this technique, such as patients with obesity and respiratory disease. In order to do so the investigators will use an up-down methodology to find the minimum volume of local anesthetic to provide sufficient anesthesia for shoulder surgery.
Popular filter options for anesthesia trials
Local Anesthesia Clinical Trials
View 17 Local Anesthesia medical studies.
Procedure
Opioid-free general anesthetic for Chronic Pain
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
Procedure
Standard Intravenous Regional Anesthesia (IVRA) with Reapplication of Esmarch for Hand Injuries and Disorders
Intravenous regional anesthesia is a commonly used technique in the outpatient setting for short hand and upper extremity cases, such as carpal tunnel release or trigger finger release. The technique requires a tourniquet, Esmarch bandage, an intravenous line, and lidocaine. It can be performed and learned easily. The technique is safe and easy to perform, and it provides adequate anesthesia for short cases; however, there are still some cases in which adequate anesthesia is not achieved. One of the possible reasons for failure is that the local anesthetic (lidocaine) does not properly exit the veins to reach the interstitial space (where many nerves are located) to provide the nerve block. In this study, the investigators hypothesize that after application of lidocaine to the intravenous system, application of external pressure through the skin will facilitate tissue penetration and improve the block. The only research procedure being done is a re-application of the Esmarch bandage; all other procedures are Standard of Care.
General Anesthesia Clinical Trials
View 12 General Anesthesia medical studies.
Corticosteroid
Anesthesia Types for Cancer Surgery
This trial is comparing two types of anesthesia during cancer surgery - one using propofol and the other using a volatile agent (sevoflurane, isoflurane, or desflurane). The goal is to see which is better at preventing death.
Procedure
Opioid-free general anesthetic for Chronic Pain
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
General Anesthetic
Anesthetics for Pain Management During Surgery
This trial will test how pain affects long-term memory and the body's conditioned responses, using MRI to track the brain's reaction. The study will take place over 5 visits, with no long-term follow up required.
Phase 3 Anesthesia Clinical Trials
View 99 phase 3 anesthesia medical studies.
Fentanyl for Low Blood Pressure
This trial will test whether or not fentanyl contributes to hypotension (low blood pressure) during the induction of general anesthesia in elderly patients. If fentanyl is found to contribute to hypotension, the study may lead to a change in clinical practice which could improve patient outcomes and mortality rates.
Procedure
Opioid-free general anesthetic for Chronic Pain
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
Anesthesia Clinical Trials With No Placebo
View 99 anesthesia medical studies that do not have a placebo group.
Face Tent Ventilation System for Risk Reduction During Pediatric Surgeries
This trial will test how well a local exhaust ventilation system (LEVS) works to reduce exposure to infectious and smoke particulates for medical providers during anesthesia-related AGMPs and pediatric surgeries.
View More Anesthesia Trials
See another 75 medical studies focused on anesthesia.
Frequently Asked Questions
Introduction to anesthesia
What are the top hospitals conducting anesthesia research?
When it comes to cutting-edge research in the field of anesthesia, several top hospitals are leading the way. In Chicago, Rush University Medical Center is at the forefront with three ongoing anesthesia trials. While they may not have a historical record of anesthesia trials, their dedication to advancing knowledge and improving patient care is evident. Similarly, Stanford University in Stanford, Royal University Hospital in Saskatoon, Washington University School of Medicine in Saint Louis, and Massachusetts General Hospital in Boston all have three active anesthesia trials but no prior history. These institutions are committed to exploring new techniques and medications to enhance the safety and efficacy of anesthesia procedures.
Anesthesia plays a crucial role in modern medicine by ensuring patients' comfort during surgical procedures or relieving pain for various medical interventions. The research conducted at these esteemed hospitals contributes to refining current practices while opening avenues for novel approaches that can revolutionize patient care. From investigating new anesthetic agents to studying innovative delivery methods and monitoring technologies, these ongoing clinical trials offer hope for advancements that will benefit patients worldwide.
Located amidst Chicago's vibrant medical community, Rush University Medical Center serves as a hub for groundbreaking research on anesthesia. Meanwhile,in California stands Stanford University- world-renowned for its contributions across multiple disciplines; now adding their expertise towards enhancing anesthesiology through rigorous studies on such critical topics.In Canada,Royal university hospital based out of Saskatoon focuses its resources toward shaping future standards within this specialty by spearheading pioneering projects.Across midwest region liesThe Washington university school of medicine located right at St.Louis where experts strive collectively striving hard pushing boundaries cultivating path-breaking discoveries contributing towards field progression.Finally situated amidst rich legacy & academic excellenceisMassachusetts general hospital nestled within heartlandofBoston holding significant acclaim globally encompassesa myriad auspicious endeavors aimedat forging breakthroughs through intrepid efforts--no exception when it comes downtoanesthesia clinical investigations
These hospitals represent beacons of innovation and collaboration within the realmofanesthesiology. By conducting these trials, theyare paving the way for safer and more effective anesthetic techniques, ultimately improving patient outcomes and transforming the landscape of anesthesia practice.
Which are the best cities for anesthesia clinical trials?
Boston, Massachusetts; Houston, Texas; and New york, New York emerge as the top cities for anesthesia clinical trials. With 15 ongoing studies in Boston focusing on areas like individualization of neuromuscular blockade and EEG monitoring, along with 10 active trials each in Houston and New York exploring various aspects of general anesthesia and other related interventions. These cities offer ample opportunities for individuals to participate in cutting-edge research that aims to advance the field of anesthesia and improve patient outcomes.
Which are the top treatments for anesthesia being explored in clinical trials?
Anesthesia research is thriving, with several exciting treatments currently under investigation in clinical trials. Leading the way is dexmedetomidine, a drug showing promise in six active anesthesia trials. Another contender gaining attention is remimazolam, which has four ongoing clinical trials dedicated to exploring its potential as an anesthetic agent. Lastly, sufentanil remains a trusted option, with three active trials investigating its efficacy and safety profile for anesthesia purposes. These innovative treatments hold great potential to revolutionize the field of anesthesia and enhance patient care globally.
What are the most recent clinical trials for anesthesia?
Exciting advancements are occurring in the field of anesthesia, with recent clinical trials exploring various approaches and interventions. One such trial investigates the efficacy of inhalational anesthesia, aiming to enhance patient outcomes during surgical procedures. Gebauers Ethyl Chloride 100% Topical Spray is also being studied as a potential anesthetic option, providing an alternative to traditional methods. Additionally, ongoing research explores different anesthesia procedures and their impact on patient comfort and safety. Another trial focuses on the use of high-dose Danavorexton as a means to improve anesthesia effectiveness. These innovative studies contribute valuable insights to optimize anesthesia practices and ultimately enhance patient care across medical settings
What anesthesia clinical trials were recently completed?
Recently, several noteworthy clinical trials in the field of anesthesia have concluded, shedding light on new possibilities for medical practice. These studies focused on exploring and evaluating different approaches to anesthesia administration and management. The trial findings provide valuable insights that can contribute to enhancing patient safety, optimizing pain control strategies, and improving overall surgical outcomes. By advancing our understanding of anesthesia techniques, these completed trials pave the way for future advancements in perioperative care.