TAP Block for Local Anesthesia

No longer recruiting at 1 trial location
GM
JH
Overseen ByJustin Hruska, MD
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: Justin Hruska
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new method of using TAP blocks, a pain relief technique, during minimally invasive gynecologic surgeries. The researchers aim to determine if administering the anesthetic while the abdomen remains inflated during surgery reduces pain more effectively than the usual method. Participants are divided into two groups: one receives the anesthetic during surgery, and the other after. Women scheduled for laparoscopic gynecologic procedures who have agreed to receive a TAP block may be suitable candidates for this trial.

As an unphased trial, this study allows participants to contribute to innovative pain management research that could enhance surgical recovery for future patients.

Do I need to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this anesthetic technique is safe for patients undergoing minimally invasive gynecologic surgeries?

Research has shown that the Transversus Abdominis Plane (TAP) block safely and effectively reduces post-surgical pain. In one study involving 511 patients, the TAP block significantly reduced pain levels. Other studies have also found that patients receiving a TAP block reported less pain compared to some other pain relief methods.

Regarding safety, TAP blocks are generally well-tolerated. Comparisons with other pain relief methods have shown them to be safe, with serious side effects being rare. Most patients do not experience major problems. Overall, the TAP block is considered safe for managing pain after surgeries.12345

Why are researchers excited about this trial?

Researchers are excited about TAP Block for local anesthesia because it offers a targeted approach to post-operative pain management. Unlike general painkillers that affect the whole body, the TAP Block specifically numbs the abdominal wall by delivering Ropivacaine directly to the nerve plane. This method may reduce the need for systemic opioids, like morphine or hydromorphone, thus potentially minimizing side effects. Additionally, performing the TAP Block in different settings, like the operating room versus the recovery unit, allows for flexible pain management strategies tailored to individual patient needs.

What evidence suggests that this technique is effective for reducing post-operative pain in minimally invasive gynecologic surgeries?

Research has shown that Transversus Abdominis Plane (TAP) blocks effectively reduce pain after surgery and lower the need for opioid painkillers. In this trial, participants will receive a TAP block either in the operating room or in the Post Anesthesia Care Unit (PACU). Studies indicate that TAP blocks provide better pain relief than a placebo, significantly reducing morphine use in the first 24 hours after surgery. A review of multiple studies suggests that TAP blocks offer pain relief similar to epidural anesthesia, commonly used in abdominal surgeries. Evidence also shows that TAP blocks can quickly ease pain after surgeries like robotic-assisted prostate removals. Overall, the TAP block is a proven method for managing pain after abdominal procedures.35678

Who Is on the Research Team?

JH

Justin Hruska, MD

Principal Investigator

Wayne State University/Detroit Medical Center

Are You a Good Fit for This Trial?

This trial is for patients undergoing minimally invasive gynecologic surgeries. Participants should be those who require post-operative pain management and are suitable candidates for receiving a Transversus Abdominis Plane (TAP) block, which is an anesthesia technique.

Inclusion Criteria

I have agreed to receive a TAP block.
I am a woman aged 18-85, scheduled for a gynecological laparoscopic procedure.

Exclusion Criteria

Patients who are not proficient in the English language or cannot consent
Patients who have an allergy to local anesthetics (amides)
My surgery involved cuts above my belly button.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo minimally invasive gynecologic surgeries with TAP blocks performed either in the operating room or in the PACU

1 day
1 visit (in-person)

Immediate Post-operative Monitoring

Participants are monitored for pain and ease of performing TAP block within 10 minutes post-surgery

10 minutes

Follow-up

Participants are monitored for pain scores and opioid consumption up to 24 hours post-surgery

24 hours

What Are the Treatments Tested in This Trial?

Interventions

  • Transversus Abdominis Plane Block
Trial Overview The study tests if performing TAP blocks while the abdomen is inflated with air during surgery leads to better pain control after surgery compared to the traditional method of doing it after deflation.
How Is the Trial Designed?
2Treatment groups
Active Control
Group I: Active Comparator: Transversus abdominis plane (TAP) block performed in operating roomActive Control1 Intervention
Group II: Transversus abdominis plane (TAP) block performed in PACUActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Justin Hruska

Lead Sponsor

Trials
1
Recruited
110+

Citations

Review Articles Transversus abdominis plane block for ...TAP block provides superior analgesia compared with placebo and can reduce the first 24 h morphine consumption in the setting of a multimodal analgesic regimen ...
Comparative Effectiveness of Transversus Abdominis ...This meta-analysis demonstrates that TAP block provides postoperative analgesia comparable to TEA for abdominal surgeries, particularly in terms of pain ...
Transversus Abdominis Plane Block Reduced Early ...These results indicated that subcostal TAP block by anesthesiologists of varied level of training reduced postoperative pain immediate after RALP.
The Efficacy of Transversus Abdominis Plane (TAP) Blocks ...Current literature has demonstrated the benefits of transversus abdominis plane (TAP) blocks for reducing postoperative pain and opioid consumption.
Navigating Pain Relief: A Comprehensive Review of ...This comprehensive review explores the multifaceted role of the transversus abdominis plane (TAP) block in contemporary pain management.
Effect of Transversus Abdominis Plane Block on Postoperative ...Results. A total of 7 RCTs with 511 patients were included. The results of this study suggested that TAP block significantly relieved postoperative pain ...
Transversus Abdominis Plane Block Versus Local ...This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients ...
Transversus abdominis-plane block versus local anesthetic ...TAP block and LAI provide comparable short-term postoperative analgesia, but TAP block has better long-lasting effect.
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