TAP Block for Local Anesthesia
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new method of using TAP blocks, a pain relief technique, during minimally invasive gynecologic surgeries. The researchers aim to determine if administering the anesthetic while the abdomen remains inflated during surgery reduces pain more effectively than the usual method. Participants are divided into two groups: one receives the anesthetic during surgery, and the other after. Women scheduled for laparoscopic gynecologic procedures who have agreed to receive a TAP block may be suitable candidates for this trial.
As an unphased trial, this study allows participants to contribute to innovative pain management research that could enhance surgical recovery for future patients.
Do I need to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this anesthetic technique is safe for patients undergoing minimally invasive gynecologic surgeries?
Research has shown that the Transversus Abdominis Plane (TAP) block safely and effectively reduces post-surgical pain. In one study involving 511 patients, the TAP block significantly reduced pain levels. Other studies have also found that patients receiving a TAP block reported less pain compared to some other pain relief methods.
Regarding safety, TAP blocks are generally well-tolerated. Comparisons with other pain relief methods have shown them to be safe, with serious side effects being rare. Most patients do not experience major problems. Overall, the TAP block is considered safe for managing pain after surgeries.12345Why are researchers excited about this trial?
Researchers are excited about TAP Block for local anesthesia because it offers a targeted approach to post-operative pain management. Unlike general painkillers that affect the whole body, the TAP Block specifically numbs the abdominal wall by delivering Ropivacaine directly to the nerve plane. This method may reduce the need for systemic opioids, like morphine or hydromorphone, thus potentially minimizing side effects. Additionally, performing the TAP Block in different settings, like the operating room versus the recovery unit, allows for flexible pain management strategies tailored to individual patient needs.
What evidence suggests that this technique is effective for reducing post-operative pain in minimally invasive gynecologic surgeries?
Research has shown that Transversus Abdominis Plane (TAP) blocks effectively reduce pain after surgery and lower the need for opioid painkillers. In this trial, participants will receive a TAP block either in the operating room or in the Post Anesthesia Care Unit (PACU). Studies indicate that TAP blocks provide better pain relief than a placebo, significantly reducing morphine use in the first 24 hours after surgery. A review of multiple studies suggests that TAP blocks offer pain relief similar to epidural anesthesia, commonly used in abdominal surgeries. Evidence also shows that TAP blocks can quickly ease pain after surgeries like robotic-assisted prostate removals. Overall, the TAP block is a proven method for managing pain after abdominal procedures.35678
Who Is on the Research Team?
Justin Hruska, MD
Principal Investigator
Wayne State University/Detroit Medical Center
Are You a Good Fit for This Trial?
This trial is for patients undergoing minimally invasive gynecologic surgeries. Participants should be those who require post-operative pain management and are suitable candidates for receiving a Transversus Abdominis Plane (TAP) block, which is an anesthesia technique.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo minimally invasive gynecologic surgeries with TAP blocks performed either in the operating room or in the PACU
Immediate Post-operative Monitoring
Participants are monitored for pain and ease of performing TAP block within 10 minutes post-surgery
Follow-up
Participants are monitored for pain scores and opioid consumption up to 24 hours post-surgery
What Are the Treatments Tested in This Trial?
Interventions
- Transversus Abdominis Plane Block
Trial Overview
The study tests if performing TAP blocks while the abdomen is inflated with air during surgery leads to better pain control after surgery compared to the traditional method of doing it after deflation.
How Is the Trial Designed?
2
Treatment groups
Active Control
The treatment group will have a transversus abdominis plane (TAP) block performed prior to closing surgical port sites post-operatively in an insufflated abdomen in the operating room (OR). The local anesthetic used for the TAP block will be 30 to 40ml of Ropivacaine 0.375%, not to exceed a max dose of 3mg/kg of 0.375% divided equally bilaterally. Each study participant will receive standard post-operative pain medication orders of morphine 2mg q5mins times 4 doses followed by hydromorphone. 0.5mg q10mins times 4 doses.
The treatment group will have a transversus abdominis plane (TAP) block performed post-operatively after the patient has been transferred from the Operating Room to the Post Anesthesia Care Unit (PACU). The local anesthetic used for the TAP block will be 30 to 40ml of Ropivacaine 0.375%, not to exceed a max dose of 3mg/kg of 0.375% divided equally bilaterally. Each study participant will receive standard post-operative pain medication orders of morphine 2mg q5mins times 4 doses followed by hydromorphone. 0.5mg q10mins times 4 doses
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Who Is Running the Clinical Trial?
Justin Hruska
Lead Sponsor
Citations
Review Articles Transversus abdominis plane block for ...
TAP block provides superior analgesia compared with placebo and can reduce the first 24 h morphine consumption in the setting of a multimodal analgesic regimen ...
Comparative Effectiveness of Transversus Abdominis ...
This meta-analysis demonstrates that TAP block provides postoperative analgesia comparable to TEA for abdominal surgeries, particularly in terms of pain ...
Transversus Abdominis Plane Block Reduced Early ...
These results indicated that subcostal TAP block by anesthesiologists of varied level of training reduced postoperative pain immediate after RALP.
The Efficacy of Transversus Abdominis Plane (TAP) Blocks ...
Current literature has demonstrated the benefits of transversus abdominis plane (TAP) blocks for reducing postoperative pain and opioid consumption.
Navigating Pain Relief: A Comprehensive Review of ...
This comprehensive review explores the multifaceted role of the transversus abdominis plane (TAP) block in contemporary pain management.
Effect of Transversus Abdominis Plane Block on Postoperative ...
Results. A total of 7 RCTs with 511 patients were included. The results of this study suggested that TAP block significantly relieved postoperative pain ...
Transversus Abdominis Plane Block Versus Local ...
This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients ...
8.
bmcanesthesiol.biomedcentral.com
bmcanesthesiol.biomedcentral.com/articles/10.1186/1471-2253-14-121Transversus abdominis-plane block versus local anesthetic ...
TAP block and LAI provide comparable short-term postoperative analgesia, but TAP block has better long-lasting effect.
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