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Los Angeles County-USC Medical Center

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Los Angeles, California 90033

Global Leader in HIV Infection

Global Leader in Human Immunodeficiency Virus Infection

Conducts research for Cancer

Conducts research for Lung Cancer

Conducts research for AIDS

499 reported clinical trials

46 medical researchers

Photo of Los Angeles County-USC Medical Center in Los AngelesPhoto of Los Angeles County-USC Medical Center in Los Angeles

Summary

Los Angeles County-USC Medical Center is a medical facility located in Los Angeles, California. This center is recognized for care of HIV Infection, Human Immunodeficiency Virus Infection, Cancer, Lung Cancer, AIDS and other specialties. Los Angeles County-USC Medical Center is involved with conducting 499 clinical trials across 731 conditions. There are 46 research doctors associated with this hospital, such as Anthony El-Khoueiry, MD, Heinz-Josef Lenz, David Hong, MD, and Jacob Thomas, MD.

Top PIs

Clinical Trials running at Los Angeles County-USC Medical Center

Cancer

Bladder Cancer

Prostate Cancer

Breast Cancer

Kidney Cancer

Esophageal cancer

Pancreatic Cancer

Colorectal Cancer

Small Cell Lung Cancer

Lung Cancer

Image of trial facility.

Chemotherapy

for Cancer

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.

Recruiting

2 awards

Phase 3

26 criteria

Image of trial facility.

Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

Image of trial facility.

Atezolizumab +/− Selinexor

for Sarcoma

This trial is testing if atezolizumab alone or with selinexor can shrink tumors in patients with a rare type of cancer called alveolar soft part sarcoma. Atezolizumab boosts the immune system to fight cancer, and selinexor stops cancer cells from growing. The goal is to see if these treatments work better than the usual care.

Recruiting

1 award

Phase 2

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