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Jonsson Comprehensive Cancer Center, UCLA

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Los Angeles, California 90095
Global Leader in Breast Cancer
Global Leader in Brain Tumor
Conducts research for Prostate Cancer
Conducts research for Leukemia
Conducts research for Lung Cancer
725 reported clinical trials
43 medical researchers
Photo of Jonsson Comprehensive Cancer Center, UCLA in Los AngelesPhoto of Jonsson Comprehensive Cancer Center, UCLA in Los AngelesPhoto of Jonsson Comprehensive Cancer Center, UCLA in Los Angeles

Summary

Jonsson Comprehensive Cancer Center, UCLA is a medical facility located in Los Angeles, California. This center is recognized for care of Breast Cancer, Brain Tumor, Prostate Cancer, Leukemia, Lung Cancer and other specialties. Jonsson Comprehensive Cancer Center, UCLA is involved with conducting 725 clinical trials across 517 conditions. There are 43 research doctors associated with this hospital, such as Zev A. Wainberg, William A. May, Theodore Moore, MD, and Bartosz Chmielowski, MD.

Area of expertise

1Breast Cancer
Global Leader
Jonsson Comprehensive Cancer Center, UCLA has run 76 trials for Breast Cancer. Some of their research focus areas include:
Stage III
Stage I
Stage II
2Brain Tumor
Global Leader
Jonsson Comprehensive Cancer Center, UCLA has run 75 trials for Brain Tumor. Some of their research focus areas include:
Stage IV
IDH negative
IDH positive

Top PIs

Clinical Trials running at Jonsson Comprehensive Cancer Center, UCLA

Prostate Cancer
Breast Cancer
Bladder Cancer
Kidney Cancer
Rectal Cancer
Cancer
Breast cancer
Bladder Carcinoma
Testicular cancer
Glioblastoma
Image of trial facility.

Apalutamide + Targeted Radiation

for Prostate Cancer

This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in patients with prostate cancer who experience biochemical recurrence (a rise in the blood level of prostate specific antigen \[PSA\] after surgical removal of the prostate cancer). A second question tests treatment in patients with biochemical recurrence who show prostate cancer spreading outside the pelvis (metastasis) by positron emission tomography (PET) imaging. In these patients, the benefit of adding metastasis-directed radiation to enhanced therapy (apalutamide in combination with abiraterone + prednisone) is tested. Diagnostic procedures, such as PET, may help doctors look for cancer that has spread to the pelvis. Androgens are hormones that may cause the growth of prostate cancer cells. Apalutamide may help fight prostate cancer by blocking the use of androgens by the tumor cells. Metastasis-directed targeted radiation therapy uses high energy rays to kill tumor cells and shrink tumors that have spread. This trial may help doctors determine if using PET results to deliver more tailored treatment (i.e., adding apalutamide, with or without targeted radiation therapy, to standard of care treatment) works better than standard of care treatment alone in patients with biochemical recurrence of prostate cancer.
Recruiting2 awards Phase 3
Image of trial facility.

Apalutamide + Hormone and Radiation Therapies

for Prostate Cancer

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. Drugs, such as apalutamide, may help stop or reduce the growth of prostate cancer cell growth by blocking the attachment of androgen to its receptors on cancer cells, a mechanism similar to stopping the entrance of a key into its lock. Adding apalutamide to the usual hormone therapy and radiation therapy after surgery may stabilize prostate cancer and prevent it from spreading and extend time without disease spreading compared to the usual approach.
Recruiting2 awards Phase 3
Image of trial facility.

177Lu-PSMA-617

for Prostate Cancer

This phase II trial tests how well re-treatment with 177Lu-PSMA-617 works in treating patients with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic), that continues to grow or spread after the surgical removal of the testes or medical treatment to block androgen production (castration-resistant), and that has shown a favorable response to initial treatment with 177Lu-PSMA-617. 177Lu-PSMA-617 is a radioactive drug. It binds to a protein called prostate specific membrane antigen (PSMA), which is expressed by some types of prostate tumor cells. When 177Lu-PSMA-617 binds to PSMA-expressing tumor cells, it delivers radiation to the cells, which may kill them. Re-treatment with 177Lu-PSMA-617 in patients who had a favorable response to initial 177Lu-PSMA-617 treatment may improve survival outcomes and disease response in patients with metastatic castration-resistant prostate cancer.
Recruiting1 award Phase 2

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Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security