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Children's Hospital Los Angeles

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Los Angeles, California 90027
Global Leader in Brain Tumor
Global Leader in Neuroblastoma
Conducts research for Cancer
Conducts research for Acute Lymphoblastic Leukemia
Conducts research for Solid Tumors
1022 reported clinical trials
64 medical researchers
Photo of Children's Hospital Los Angeles in Los AngelesPhoto of Children's Hospital Los Angeles in Los AngelesPhoto of Children's Hospital Los Angeles in Los Angeles

Summary

Children's Hospital Los Angeles is a medical facility located in Los Angeles, California. This center is recognized for care of Brain Tumor, Neuroblastoma, Cancer, Acute Lymphoblastic Leukemia, Solid Tumors and other specialties. Children's Hospital Los Angeles is involved with conducting 1,022 clinical trials across 1,254 conditions. There are 64 research doctors associated with this hospital, such as Leo Mascarenhas, MD, Fariba Navid, MD, Nathan Robison, MD, and Michael Pulsipher, MD.

Area of expertise

1Brain Tumor
Global Leader
Children's Hospital Los Angeles has run 102 trials for Brain Tumor. Some of their research focus areas include:
Stage IV
BRAF positive
Stage II
2Neuroblastoma
Global Leader
Children's Hospital Los Angeles has run 99 trials for Neuroblastoma. Some of their research focus areas include:
MYC positive
Stage IV
MYC negative

Top PIs

Clinical Trials running at Children's Hospital Los Angeles

Brain Tumor
Neuroblastoma
Cancer
Leukemia
Brain Cancer
Testicular cancer
Acute Lymphoblastic Leukemia
Autism Spectrum Disorder
Hemophilia
Ovarian Carcinoma
Image of trial facility.

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Image of trial facility.

DAY101 vs. Chemotherapy

for Pediatric Brain Cancer

This trial is testing tovorafenib, a medication given alone, in children with a specific type of brain tumor. The drug works by blocking a protein that helps cancer cells grow.
Recruiting2 awards Phase 3
Image of trial facility.

CAR T-Cell Therapy

for Pediatric Brain Cancer

This phase I trial investigates the side effects of chemotherapy and cellular immunotherapy in treating children with IL13Ralpha2 positive brain tumors that have come back after a period of improvement (recurrent) or do not respond to treatment (refractory). Cellular immunotherapy (IL13(EQ)BBzeta/CD19t+ T cells) are brain-tumor specific cells that may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as as cyclophosphamide and fludarabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Many patients with brain tumor respond to treatment, but then the tumor starts to grow again. Giving chemotherapy in combination with cellular immunotherapy may kill more tumor cells and improve the outcome of treatment.
Recruiting1 award Phase 154 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security