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Lahey Hospital and Medical Center
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Burlington, Massachusetts 01803
Global Leader in Lung Cancer
Global Leader in Breast Cancer
Conducts research for Non-Small Cell Lung Cancer
Conducts research for Breast cancer
Conducts research for Cancer
472 reported clinical trials
33 medical researchers
Summary
Lahey Hospital and Medical Center is a medical facility located in Burlington, Massachusetts. This center is recognized for care of Lung Cancer, Breast Cancer, Non-Small Cell Lung Cancer, Breast cancer, Cancer and other specialties. Lahey Hospital and Medical Center is involved with conducting 472 clinical trials across 608 conditions. There are 33 research doctors associated with this hospital, such as Corrine Zarwan, MD, Brendan Connell, Paul J. Hesketh, and Ragisha Gopalakrishnan.
Area of expertise
Lung Cancer
Lahey Hospital and Medical Center has run 63 trials for Lung Cancer. Some of their research focus areas include:
Breast Cancer
Lahey Hospital and Medical Center has run 59 trials for Breast Cancer. Some of their research focus areas include:
Top PIs
Corrine Zarwan, MD
Lahey Hospital and Medical Center
9 years of reported clinical research
Brendan Connell
Lahey Hospital and Medical Center
5 years of reported clinical research
Paul J. Hesketh
Lahey Hospital and Medical Center
5 years of reported clinical research
Ragisha Gopalakrishnan
Mount Sinai Medical Center
2 years of reported clinical research
Clinical Trials running at Lahey Hospital and Medical Center
Lung Cancer
Bladder Cancer
Breast Cancer
Kidney Cancer
Cancer
Bladder Carcinoma
Breast cancer
Prostate Cancer
Non-Small Cell Lung Cancer
Stroke
Immunotherapy + Chemotherapy
for Non-Small Cell Lung Cancer
This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.
Recruiting
2 awards
Phase 3
27 criteria
Treatment Timing
for Non-Small Cell Lung Cancer
This phase III trial compares standard therapy given after surgery (adjuvant) to standard therapy given before and after surgery (perioperative) in treating patients with stage II-IIIB non-small cell lung cancer (NSCLC) that can be removed by surgery (resectable). The usual approach for patients with resectable NSCLC is chemotherapy and/or immunotherapy before surgery, after surgery, or both before and after surgery. This study is being done to find out which approach is better at treating patients with lung cancer. Treatment will be administered according to the current standard of care at the time of enrollment. Chemotherapy options may include cisplatin, carboplatin, pemetrexed, gemcitabine, docetaxel, and vinorelbine at standard doses according to the treating physician. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of tumor cells. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by stopping cells from using folic acid to make deoxyribonucleic acid (DNA) and may kill tumor cells. Gemcitabine is a chemotherapy drug that blocks the cells from making DNA and may kill tumor cells. Docetaxel is in a class of medications called taxanes. It stops tumor cells from growing and dividing and may kill them. Other chemotherapy drugs, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading . Immunotherapy with monoclonal antibodies, such as nivolumab, pembrolizumab, and atezolizumab, may help the body's immune system attack the tumor, and may interfere with the ability of tumor cells to grow and spread. Starting treatment with chemotherapy and immunotherapy prior to surgery and continuing treatment after surgery may be a more effective treatment option than adjuvant therapy alone in patients with stage II-IIIB resectable NSCLC.
Recruiting
2 awards
Phase 3
4 criteria
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting
2 awards
Phase 3
31 criteria
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Frequently asked questions
What kind of research happens at Lahey Hospital and Medical Center?
Lahey Hospital and Medical Center is a medical facility located in Burlington, Massachusetts. This center is recognized for care of Lung Cancer, Breast Cancer, Non-Small Cell Lung Cancer, Breast cancer, Cancer and other specialties. Lahey Hospital and Medical Center is involved with conducting 472 clinical trials across 608 conditions. There are 33 research doctors associated with this hospital, such as Corrine Zarwan, MD, Brendan Connell, Paul J. Hesketh, and Ragisha Gopalakrishnan.
Where is Lahey Hospital and Medical Center located?
To reach Lahey Hospital and Medical Center in Burlington, Massachusetts: Take I-95 N to exit 33B for Route 3 N towards Burlington. Follow Route 3 N, then use the right 2 lanes to take exit 26 for Route 128 S/I-95 S towards Waltham. Continue on Route 128 S for 2 miles, then take exit 33B for Route 3 N towards Burlington.
Who should I call to ask about financial aid or insurance network?
**Lahey Hospital and Medical Center Contact Information:** - **Billing Inquiries:** Patient Accounts Department, 781-744-5800 - **Financial Assistance:** Financial Counseling Department, 781-744-8815 - **Insurance Questions:** Insurance and Billing Department, 781-744-5800 - **General Inquiries:** Customer Relationship Management Department, 781-744-8556
What insurance does Lahey Hospital and Medical Center accept?
Lahey Hospital and Medical Center accepts most health insurance plans, including Medicare and Massachusetts Medicaid. They specifically accept plans from Aetna, Inc., AllWays Health Partners, Anthem Blue Cross Blue Shield of New Hampshire, and many others, covering a wide range of services. For the most current information, contacting Lahey Hospital and Medical Center directly is recommended.
What awards or recognition has Lahey Hospital and Medical Center received?
Lahey Hospital & Medical Center, located in Burlington, Massachusetts, actively supports community health through significant funding and initiatives. In February 2023, it awarded $238,000 to 13 community-based organizations to enhance food access, mental health, transportation, and housing stability. Furthermore, from 2024 to 2027, the hospital will allocate $988,105.06 to programs addressing community needs, alongside participating in numerous clinical trials across various medical specialties.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.