Dr. Corrine Zarwan, MD
Claim this profileLahey Hospital and Medical Center
Expert in Parotid Gland Cancer
Studies Breast Cancer
16 reported clinical trials
47 drugs studied
Area of expertise
1Parotid Gland Cancer
Global LeaderHER2 positive
ER positive
Stage III
2Breast Cancer
ER positive
Stage IV
HER2 positive
Affiliated Hospitals
Clinical Trials Corrine Zarwan, MD is currently running
Durvalumab + Chemotherapy
for Breast Cancer
This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint High 2 Risk (MP2) stage II-III hormone receptor positive, HER2 negative breast cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as paclitaxel, doxorubicin, and cyclophosphamide work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. There is some evidence from previous clinical trials that people who have a MammaPrint High 2 Risk result may be more likely to respond to chemotherapy and immunotherapy. Adding durvalumab to usual chemotherapy may be able to prevent the cancer from returning for patients with MP2 stage II-III hormone receptor positive, HER2 negative breast cancer.
Recruiting2 awards Phase 340 criteria
Marker-Directed Monitoring
for Breast Cancer
This trial studies if using blood tests to decide when to do scans is as effective as the standard way for monitoring patients with a specific type of breast cancer that has spread. The blood tests act like an early warning system for cancer activity.
Recruiting1 award N/A
More about Corrine Zarwan, MD
Clinical Trial Related8 years of experience running clinical trials · Led 16 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Corrine Zarwan, MD has experience with
- Paclitaxel
- Atezolizumab
- Trastuzumab
- Pertuzumab
- Capivasertib
- Durvalumab
Breakdown of trials Corrine Zarwan, MD has run
Parotid Gland Cancer
Breast Cancer
Breast cancer
Ovarian Cancer
Cervical Adenocarcinoma
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