Dr. Brendan Connell
Claim this profileLahey Hospital and Medical Center
Studies Skin Cancer
Studies Lung Cancer
14 reported clinical trials
38 drugs studied
Area of expertise
1Skin Cancer
Stage IV
Stage III
EGFR positive
2Lung Cancer
Stage IV
Stage III
Stage II
Affiliated Hospitals
Clinical Trials Brendan Connell is currently running
Tivozanib + Pembrolizumab
for Kidney Cancer
This phase III trial compares the effect of adding tivozanib to standard therapy pembrolizumab versus pembrolizumab alone for the treatment of patients with high-risk renal cell carcinoma (RCC). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Tivozanib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals tumor cells to multiply. This helps stop the spread of tumor cells. Giving pembrolizumab and tivozanib together may work better than pembrolizumab alone in treating patients with RCC.
Recruiting2 awards Phase 37 criteria
Immunotherapy + Targeted Therapy
for Genitourinary Cancers
This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.
Recruiting1 award Phase 221 criteria
More about Brendan Connell
Clinical Trial Related5 years of experience running clinical trials · Led 14 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Brendan Connell has experience with
- Pembrolizumab
- Darolutamide
- Nivolumab
- Avelumab
- Ipilimumab
- Docetaxel
Breakdown of trials Brendan Connell has run
Skin Cancer
Lung Cancer
Prostate Cancer
Non-Small Cell Lung Cancer
Kidney Cancer
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