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Burlington

University of Vermont Medical Center

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Burlington, Vermont 05401

Global Leader in Breast Cancer

Global Leader in Cancer

Conducts research for Lung Cancer

Conducts research for Brain Tumor

Conducts research for Lymphoma

524 reported clinical trials

48 medical researchers

Photo of University of Vermont Medical Center in BurlingtonPhoto of University of Vermont Medical Center in Burlington

Summary

University of Vermont Medical Center is a medical facility located in Burlington, Vermont. This center is recognized for care of Breast Cancer, Cancer, Lung Cancer, Brain Tumor, Lymphoma and other specialties. University of Vermont Medical Center is involved with conducting 524 clinical trials across 1,050 conditions. There are 48 research doctors associated with this hospital, such as Jessica L. Heath, Alissa Thomas, Steven Ades, M.D., and Marie Wood.

Area of expertise

1

Breast Cancer

Global Leader

University of Vermont Medical Center has run 77 trials for Breast Cancer. Some of their research focus areas include:

HER2 negative
ER positive
Stage IV
2

Cancer

Global Leader

University of Vermont Medical Center has run 77 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage III

Top PIs

Clinical Trials running at University of Vermont Medical Center

Breast Cancer

Skin Cancer

Esophageal cancer

Cancer

Breast cancer

Lung Cancer

Acute Myeloid Leukemia

Prostate Cancer

Heart Failure

Testicular cancer

Image of trial facility.

Radiation and HER2-Targeted Therapy

for Breast Cancer

This Phase III trial compares the recurrence-free interval (RFI) among patients with early-stage, low risk HER2+ breast cancer who undergo breast conserving surgery and receive HER2-directed therapy, and are randomized to not receive adjuvant breast radiotherapy versus those who are randomized to receive adjuvant radiotherapy per the standard of care.

Recruiting

2 awards

Phase 3

15 criteria

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Low Dose Tamoxifen

for Breast Cancer

This phase III trial compares the effect of low dose tamoxifen to usual hormonal therapy, including aromatase inhibitors, in treating post-menopausal women with hormone positive, HER2 negative early stage breast cancer. Tamoxifen is in a class of medications known as antiestrogens. It blocks the activity of estrogen (a female hormone) in the breast. This may stop the growth of some breast tumors that need estrogen to grow. Aromatase inhibitors, such as anastrozole, letrozole, and exemestane, prevent the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy to treat postmenopausal women with hormone-dependent breast cancer. Giving low dose tamoxifen may be more effective compared to usual hormone therapy in treating post-menopausal women with hormone-positive, HER2 negative early stage breast cancer.

Recruiting

2 awards

Phase 3

8 criteria

Image of trial facility.

Radiation Therapy

for Brain Metastasis

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. FSRS delivers a high dose of radiation to the tumor over 3 treatments. SRS is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. FSRS may be more effective compared to SRS in treating patients with cancer that has spread to the brain.

Recruiting

2 awards

Phase 3

12 criteria

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