Single-Session Interventions for Depression
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether new digital single-session interventions (SSIs) can reduce depression in American adults. It tests 11 different SSIs, such as mindfulness, expressive writing, and cognitive reappraisal, against a simple control activity. Participants will engage in these brief online sessions to determine which ones most effectively improve mood. This trial suits individuals experiencing moderate depression who can access the internet for two sessions over four weeks. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could shape future mental health treatments.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that many single-session treatments (SSIs) for depression have been safe in past studies. Mindfulness techniques, such as Mindful Attention Skills and Mindful Acceptance, are typically safe and have been linked to reduced depression and anxiety. Studies suggest these mindfulness methods can improve mental health with minimal risks.
Dialectical Behavioral Therapy Skills have also been tested for safety and show promise in reducing depression symptoms. Although some individuals may experience worsening symptoms, the therapy is generally safe, especially with professional guidance.
Cognitive Reappraisal, which involves changing thoughts about negative situations, is another well-researched method. Research suggests it can help reduce negative feelings and is generally safe for mental health use.
Expressive Writing, even when aided by AI, has been shown to improve mental health. Experts indicate it is a safe way to help individuals express and process their thoughts and feelings.
Moral Elevation, which involves feeling inspired by acts of kindness, has been linked to positive emotions. Studies have not identified significant safety concerns with this approach.
Lastly, Personalized Intervention Recommenders and other digital tools are becoming more common. Reviews show these digital mental health tools are generally well-received, with ongoing research ensuring their safety and effectiveness.
Overall, these treatments are designed to be safe and helpful, with the potential to improve mental health through various innovative methods.12345Why are researchers excited about this trial?
Researchers are excited about these single-session interventions for depression because they offer quick, accessible ways to manage symptoms without the need for prolonged therapy. Unlike traditional treatments like antidepressants or weekly therapy sessions, these interventions can provide immediate tools for coping with negative thoughts and emotions. For example, the "Interactive Cognitive Reappraisal" teaches participants to reframe negative thoughts in a single session, while the "Inner Child Healing Walk" uses breathing exercises and positive affirmations to promote self-compassion. These innovative approaches aim to empower individuals by offering practical strategies that can be easily integrated into daily life, potentially transforming how depression is managed.
What evidence suggests that this trial's treatments could be effective for depression?
Research shows that single-session interventions (SSIs) can effectively reduce symptoms of depression. In this trial, participants may receive different SSIs, such as "5 Habits to Beat Depression," which studies have shown can significantly reduce depression and anxiety, especially when offered online. Another option in this trial is the "Interactive Cognitive Reappraisal" method, which involves learning to change negative thoughts and has shown promise in improving mental health, with some studies indicating small to medium benefits. Additionally, participants might experience the "Inner Child Healing Walk" or other mindfulness-based activities, which can help lower stress and anxiety. Overall, these digital interventions provide a quick and easy way to address depression symptoms.678910
Are You a Good Fit for This Trial?
This trial is for American adults who can access the internet to complete sessions over four weeks, read and write English fluently, have moderate depression (scoring at least 10 on the PHQ-9), pass attention checks, and are at least 18 years old. Those not participating seriously will be excluded.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants engage in a single-session intervention (SSI) to address depression, which includes various digital formats such as videos, interactive exercises, and audio programs.
Follow-up
Participants are monitored for changes in depression symptoms and other psychological measures at week 4.
What Are the Treatments Tested in This Trial?
Interventions
- 5 Habits to Beat Depression
- All about Trout
- Behavioral Activation (Action Brings Change Project 10-Minute Version)
- Dialectical Behavioral Therapy Skills
- Expressive Writing (AI-supported)
- Inner Child Healing Walk
- Interactive Cognitive Reappraisal
- Mindful Acceptance
- Mindful Attention Skills
- Moral Elevation
- Personalized Intervention Recommender
- Reframing Negative Thoughts
- Savoring Strategies
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator