ResArgin for Weight Loss
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether ResArgin, a resveratrol-based supplement, can slow muscle loss during fat loss. It also examines its effects on sleep, mood, activity levels, and body satisfaction. Researchers compare ResArgin to a placebo to determine its true impact. Ideal participants are overweight or mildly obese adults without major metabolic or endocrine issues. Participants will take either ResArgin or a placebo daily for three months and record their mood and health in a diary. As an unphased trial, this study provides a unique opportunity to contribute to scientific understanding and potentially enhance personal health outcomes.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is there any evidence suggesting that ResArgin is likely to be safe for humans?
Research has shown that resveratrol, the main ingredient in ResArgin, is generally safe when consumed in small amounts, such as those found in foods. In studies where participants took higher doses—up to 1000 mg daily for 90 days—most tolerated it well. Some experienced mild stomach issues like nausea and diarrhea, especially at doses over a gram. However, this trial uses only 50 mg per day, much lower than the doses that caused these side effects. Overall, resveratrol has been shown to be safe for most people, but it's important to monitor how the body reacts.12345
Why are researchers excited about this trial?
ResArgin is unique because it leverages trans-Resveratrol, a compound found in red wine and certain plants, known for its antioxidant properties. Unlike many standard weight loss treatments, which often focus on appetite suppression or fat absorption, ResArgin may aid weight loss through its potential to enhance metabolism and improve cellular energy efficiency. Researchers are excited about this treatment because it offers a natural, plant-based alternative that might not only help with weight management but also offer additional health benefits due to its antioxidant effects.
What evidence suggests that ResArgin might be an effective treatment for muscle loss?
Research has shown that resveratrol, the main ingredient in ResArgin, produces mixed results in weight loss studies. Some studies suggest that resveratrol can help reduce weight, lower body mass index (BMI), and decrease fat while increasing muscle. However, other studies indicate that resveratrol might not significantly affect weight loss or BMI. Despite these mixed results, resveratrol has shown potential to improve metabolism, such as reducing insulin resistance, in animal studies. Overall, while some evidence suggests resveratrol might help with weight and muscle, more research is needed to confirm its effectiveness. Participants in this trial will receive either ResArgin or a placebo to further investigate these effects.678910
Are You a Good Fit for This Trial?
This trial is for adults looking to lose weight without losing muscle. Participants must be willing to take a daily supplement (ResArgin or placebo) and keep a diary of their mood and health for 3 months. Specific inclusion and exclusion criteria are not provided, but typically involve age, health status, and commitment to the study protocol.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants take ResArgin or the placebo daily for 3 months to assess muscle loss and related health outcomes
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- ResArgin
Trial Overview
The trial tests if ResArgin can help maintain muscle during weight loss compared to a placebo. It also examines whether ResArgin affects sleep quality, activity levels, mood, and body satisfaction over three monthly assessments.
How Is the Trial Designed?
2
Treatment groups
Active Control
Placebo Group
A resveratrol-based supplement. Participants will receive a daily oral dose of ResArgin containing \[50 mg/d\] of trans-Resveratrol for 90 days.
Placebo consists of oat hull. Participants receive a daily oral dose of a placebo matching the appearance and dosage form of ResArgin for 90 days.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dr. Heather Hausenblaus
Lead Sponsor
Citations
Resveratrol for Weight Loss in Obesity: An Assessment of ...
In animal studies, resveratrol was beneficial in reducing obesity-related adverse metabolic outcomes including insulin resistance, body weight, ...
Meta-analysis What is the effect of resveratrol on obesity? ...
The study found that resveratrol supplementation does not have an anti-obesity effect, with no significant effect on weight loss or BMI.
ResArgin for Weight Loss · Info for Participants
The trial aims to see if ResArgin slows muscle loss during fat loss, and if it affects sleep, mood, activity, and body satisfaction, compared to a placebo.
The effects of resveratrol intake on weight loss
The current meta-analysis demonstrated that resveratrol intake significantly reduced weight, BMI, WC and fat mass, and significantly increased lean mass.
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torrens.figshare.com
torrens.figshare.com/articles/journal_contribution/Resveratrol_for_Weight_Loss_in_Obesity_An_Assessment_of_Randomized_Control_Trial_Designs_in_ClinicalTrials_gov/30183721Resveratrol for Weight Loss in Obesity : An Assessment of ...
Resveratrol is a polyphenol that may improve weight loss outcomes in obese individuals. However, assessing the effectiveness of resveratrol ...
Resveratrol Supplements: Side Effects and Benefits
When you get resveratrol in the amount naturally found in foods, it is generally considered safe. It could cause a reaction in those who are ...
Safety and metabolic outcomes of resveratrol ...
In summary, our findings indicate that daily resveratrol supplementation at doses of 300 mg and 1000 mg for a period of 90 days is generally well tolerated in ...
Resveratrol - Uses, Side Effects, and More
It may be helpful for hay fever and weight loss. Resveratrol might have many effects in the body, including expanding blood vessels and reducing blood clotting.
Side Effects of Resveratrol Supplements
Daily doses of resveratrol in excess of a gram commonly cause mild to moderate gastrointestinal symptoms, such as nausea, diarrhea, and abdominal pain, as well ...
Potential Adverse Effects of Resveratrol: A Literature Review
Although many studies have indicated that RE is a well-tolerated and safe compound in humans [59,60], others have reported toxic effects of RE in vitro and in ...
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