Dental Implants with Bone Grafts for Toothless Patients
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing new tooth-based bone grafts against standard human bone grafts in patients needing bone grafts for dental implants. The grafts help new bone grow to support the implants by acting like a scaffold.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but if you are using bisphosphonates, you cannot participate.
Is the use of dentin grafts for dental implants safe?
How is the treatment using Autogenous Mineralized and Demineralized Dentin Grafts for dental implants unique?
This treatment is unique because it uses the patient's own teeth, processed into a demineralized dentin matrix, as a graft material. This approach leverages the natural similarity between tooth and bone, providing growth factors that support bone regeneration, and avoids the need for additional surgeries to harvest bone from other parts of the body.15678
What data supports the effectiveness of the treatment Autogenous Mineralized and Demineralized Dentin Grafts for dental implant placement?
Research shows that using dentin grafts, made from a patient's own teeth, can effectively support new bone growth needed for dental implants. Studies have found high implant survival rates and successful bone formation with minimal complications, suggesting this method is a reliable option for patients needing dental implants.3691011
Who Is on the Research Team?
Robin Henderson, DDS, MS
Principal Investigator
University of Oklahoma
Are You a Good Fit for This Trial?
This trial is for adults aged 18 to 80 with well-controlled health conditions, who need dental implants and can consent to study requirements. It's not for those with recent head/neck radiation, active gum disease, uncontrolled health issues, heavy smokers, bisphosphonate users, or pregnant/lactating women.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgical Intervention
Surgical intervention for implant placement for all groups
Follow-up
Participants are monitored for implant stability and bone level changes
Restoration
Restoration of the implant by the restorative dentist
What Are the Treatments Tested in This Trial?
Interventions
- Autogenous Mineralized and Demineralized Dentin Grafts
- Dental Implant Placement
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Oklahoma
Lead Sponsor
Zimmer Biomet
Industry Sponsor
Dr. Nitin Goyal
Zimmer Biomet
Chief Medical Officer since 2021
MD from Harvard Medical School
Ivan Tornos
Zimmer Biomet
Chief Executive Officer since 2023
MBA from the University of Miami School of Business, BBA in Finance and International Marketing and Management from the University of Georgia Terry College of Business