Study Summary
This trial will test how using tech like smartphone apps to educate people with axial spondyloarthritis on physical activity can improve their quality of life.
Eligible Conditions
- Ankylosing Spondylitis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
5 Primary · 7 Secondary · Reporting Duration: Assessed electronically by an e-survey platform at baseline, 3, 6, 9 and 12 weeks in the intervention and control groups.
Assessed at 12 weeks.
Acceptance of health technology-based intervention strategy, as measured by the Mobile Application Rating Scale
Number of enrolled participants who complete the study
Week 12
Change in functioning and health as a result of the technology-based intervention strategy as measured by the ASAS Health Index
Change in levels of physical activity as measured by Accelerometry
Change in perceived benefits and barriers to exercise as a result of the technology-based intervention strategy as measured by the Exercise Benefits/Barriers Scale (EBBS)
Week 12
Changes in exercise behaviour as measured by an adapted Stanford Exercise Behaviours Questionnaire
Changes in levels of physical activity as measured by the International Physical Activity Questionnaire-Short Form questionnaire (IPAQ-SF)
Week 12
Disease
Change in function over the course of 12 weeks as measured by the Bath Ankylosing Spondylitis Functional Index (BASFI) questionnaire
Duration of physical activity sessions as a result of the technology-based intervention strategy over the course of 12 weeks
Frequency of physical activity sessions as a result of the technology-based intervention strategy over the course of 12 weeks
Number of accepted invites over the course of 12 weeks
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Control Group
1 of 2
Intervention Group
1 of 2
Active Control
Experimental Treatment
106 Total Participants · 2 Treatment Groups
Primary Treatment: Intervention Group · No Placebo Group · N/A
Intervention Group
Other
Experimental Group · 1 Intervention: Health technology-based intervention strategy · Intervention Types: OtherControl GroupNoIntervention Group · 1 Intervention: Control Group · Intervention Types:
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: assessed electronically by an e-survey platform at baseline, 3, 6, 9 and 12 weeks in the intervention and control groups.
Who is running the clinical trial?
Canadian Initiative for Outcomes in Rheumatology CareOTHER
5 Previous Clinical Trials
474 Total Patients Enrolled
University Health Network, TorontoLead Sponsor
1,386 Previous Clinical Trials
471,863 Total Patients Enrolled
Laura PassalentPrincipal InvestigatorUniversity Health Network, Toronto
Eligibility Criteria
Age 18+ · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Oregon | 100.0% |
What portion of applicants met pre-screening criteria?
| Did not meet criteria | 100.0% |
References
- Miller MG, Herniman JJ, Ricard MD, Cheatham CC, Michael TJ. The effects of a 6-week plyometric training program on agility. J Sports Sci Med. 2006 Sep 1;5(3):459-65. eCollection 2006.
- Lorig K, Stewart A, Ritter P, Gonzalez V, Laurent D, Lynch J. Outcome measures for health education and other health care interventions. Thousand Oaks, CA; Sage Publications, 1996, pp.25,37-38
- Doward LC, Spoorenberg A, Cook SA, Whalley D, Helliwell PS, Kay LJ, McKenna SP, Tennant A, van der Heijde D, Chamberlain MA. Development of the ASQoL: a quality of life instrument specific to ankylosing spondylitis. Ann Rheum Dis. 2003 Jan;62(1):20-6.
- Rausch Osthoff AK, Niedermann K, Braun J, Adams J, Brodin N, Dagfinrud H, Duruoz T, Esbensen BA, Günther KP, Hurkmans E, Juhl CB, Kennedy N, Kiltz U, Knittle K, Nurmohamed M, Pais S, Severijns G, Swinnen TW, Pitsillidou IA, Warburton L, Yankov Z, Vliet Vlieland TPM. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. Ann Rheum Dis. 2018 Sep;77(9):1251-1260. doi: 10.1136/annrheumdis-2018-213585. Epub 2018 Jul 11.
- Feldtkeller E, Vosse D, Geusens P, van der Linden S. Prevalence and annual incidence of vertebral fractures in patients with ankylosing spondylitis. Rheumatol Int. 2006 Jan;26(3):234-9. Epub 2005 Mar 11.
- Dagfinrud H, Kvien TK, Hagen KB. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD002822. doi: 10.1002/14651858.CD002822.pub3. Review.
- Marcolino MS, Oliveira JAQ, D'Agostino M, Ribeiro AL, Alkmim MBM, Novillo-Ortiz D. The Impact of mHealth Interventions: Systematic Review of Systematic Reviews. JMIR Mhealth Uhealth. 2018 Jan 17;6(1):e23. doi: 10.2196/mhealth.8873. Review.
- Neuberger GB, Kasal S, Smith KV, Hassanein R, DeViney S. Determinants of exercise and aerobic fitness in outpatients with arthritis. Nurs Res. 1994 Jan-Feb;43(1):11-7.
- Hillsdon M, Foster C, Thorogood M. Interventions for promoting physical activity. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD003180. Review.
- 1. World Health Organization. Fact Sheet Updated February 2018. Available at: http://www.who.int/mediacentre/factsheets/fs385/en/ Accessed on March 26, 2018
- Fanning J, Mullen SP, McAuley E. Increasing physical activity with mobile devices: a meta-analysis. J Med Internet Res. 2012 Nov 21;14(6):e161. doi: 10.2196/jmir.2171.
- Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J, Braun J, Chou CT, Collantes-Estevez E, Dougados M, Huang F, Gu J, Khan MA, Kirazli Y, Maksymowych WP, Mielants H, Sørensen IJ, Ozgocmen S, Roussou E, Valle-Oñate R, Weber U, Wei J, Sieper J. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009 Jun;68(6):777-83. doi: 10.1136/ard.2009.108233. Epub 2009 Mar 17. Erratum in: Ann Rheum Dis. 2019 Jun;78(6):e59.
- Orr, Jayne A., and Robert J. King. 2015. “Mobile Phone SMS Messages Can Enhance Healthy Behaviour: A Meta-analysis of Randomised Controlled Trials”. Health Psychology Review. Informa UK Limited. doi:10.1080/17437199.2015.1022847.
- American College of Sports Medicine Exercise pre-participation health screening recommendations. 2015 Available at: http://www.acsm.org/docs/default-source/publications/acsm-101-prescreeninginfographiccolorlegal-2015-12-15-v02.pdf?sfvrsn=2 . Accessed on March 28, 2018
- Jahangiry L, Farhangi MA, Shab-Bidar S, Rezaei F, Pashaei T. Web-based physical activity interventions: a systematic review and meta-analysis of randomized controlled trials. Public Health. 2017 Nov;152:36-46. doi: 10.1016/j.puhe.2017.06.005. Epub 2017 Jul 20. Review.
- van der Heijde D, Ramiro S, Landewé R, Baraliakos X, Van den Bosch F, Sepriano A, Regel A, Ciurea A, Dagfinrud H, Dougados M, van Gaalen F, Géher P, van der Horst-Bruinsma I, Inman RD, Jongkees M, Kiltz U, Kvien TK, Machado PM, Marzo-Ortega H, Molto A, Navarro-Compàn V, Ozgocmen S, Pimentel-Santos FM, Reveille J, Rudwaleit M, Sieper J, Sampaio-Barros P, Wiek D, Braun J. 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. Ann Rheum Dis. 2017 Jun;76(6):978-991. doi: 10.1136/annrheumdis-2016-210770. Epub 2017 Jan 13. Review.
- Trost SG, McIver KL, Pate RR. Conducting accelerometer-based activity assessments in field-based research. Med Sci Sports Exerc. 2005 Nov;37(11 Suppl):S531-43. Review.
- World Health Organization. Physical activity. Available at: http://www.who.int/topics/physical_activity/en/ Accessed on March 29, 2018
- Klingberg E, Lorentzon M, Mellström D, Geijer M, Göthlin J, Hilme E, Hedberg M, Carlsten H, Forsblad-d'Elia H. Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment. Arthritis Res Ther. 2012 May 8;14(3):R108. doi: 10.1186/ar3833.
- O'Dwyer T, McGowan E, O'Shea F, Wilson F. Physical Activity and Exercise: Perspectives of Adults With Ankylosing Spondylitis. J Phys Act Health. 2016 May;13(5):504-13. doi: 10.1123/jpah.2015-0435. Epub 2015 Oct 28.
- Haglund E, Bremander A, Bergman S, Larsson I. Educational needs in patients with spondyloarthritis in Sweden - a mixed-methods study. BMC Musculoskelet Disord. 2017 Aug 2;18(1):335. doi: 10.1186/s12891-017-1689-8.
- Wendel-Vos GC, Schuit AJ, Saris WH, Kromhout D. Reproducibility and relative validity of the short questionnaire to assess health-enhancing physical activity. J Clin Epidemiol. 2003 Dec;56(12):1163-9.
- Canadian Society for Exercise Physiology. Canadian physical activity guidelines. 2011. Available at http://www.csep.ca/CMFiles/Guidelines/CanadianPhysicalActivityGuidelinesStatements_E%203.pdf. Accessed on March 29, 2018
- Tyrrell JS, Redshaw CH. Physical Activity in Ankylosing Spondylitis: evaluation and analysis of an eHealth tool. J Innov Health Inform. 2016 Jul 4;23(2):169. doi: 10.14236/jhi.v23i2.169.
- Arturi P, Schneeberger EE, Sommerfleck F, Buschiazzo E, Ledesma C, Maldonado Cocco JA, Citera G. Adherence to treatment in patients with ankylosing spondylitis. Clin Rheumatol. 2013 Jul;32(7):1007-15. doi: 10.1007/s10067-013-2221-7. Epub 2013 Mar 21.
- Lawson D, Passalent L, Kang R, Hawke C, Omar A, Thavaneswaran A, Haroon N, Inman RD. Impact of e-learning on perceived social role participation of patients with axial spondyloarthritis: results from a longitudinal randomized control train [abstract]. Arthritis Rheumatol. 2016;68 (suppl 10)
- Dursun N, Sarkaya S, Ozdolap S, Dursun E, Zateri C, Altan L, Birtane M, Akgun K, Revzani A, Aktas İ, Tastekin N, Celiker R. Risk of falls in patients with ankylosing spondylitis. J Clin Rheumatol. 2015 Mar;21(2):76-80. doi: 10.1097/RHU.0000000000000216.
- Passalent LA, Soever LJ, O'Shea FD, Inman RD. Exercise in ankylosing spondylitis: discrepancies between recommendations and reality. J Rheumatol. 2010 Apr;37(4):835-41. doi: 10.3899/jrheum.090655. Epub 2010 Mar 1.
- Foster C, Richards J, Thorogood M, Hillsdon M. Remote and web 2.0 interventions for promoting physical activity. Cochrane Database Syst Rev. 2013 Sep 30;9:CD010395. [Epub ahead of print]
- Griffiths AJ, White CM, Thain PK, Bearne LM. The effect of interactive digital interventions on physical activity in people with inflammatory arthritis: a systematic review. Rheumatol Int. 2018 Sep;38(9):1623-1634. doi: 10.1007/s00296-018-4010-8. Epub 2018 Mar 19.
- Kim, Jeehyoung, and Wonshik Shin. 2014. “How to Do Random Allocation (randomization)”. Clinics in Orthopedic Surgery. The Korean Orthopaedic Association. doi:10.4055/cios.2014.6.1.103.
- Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, Dougados M, Hermann KG, Landewé R, Maksymowych W, van der Heijde D. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009 Jun;68 Suppl 2:ii1-44. doi: 10.1136/ard.2008.104018.
- Swinnen TW, Scheers T, Lefevre J, Dankaerts W, Westhovens R, de Vlam K. Physical activity assessment in patients with axial spondyloarthritis compared to healthy controls: a technology-based approach. PLoS One. 2014 Feb 28;9(2):e85309. doi: 10.1371/journal.pone.0085309. eCollection 2014.
- O'Dwyer T, O'Shea F, Wilson F. Decreased physical activity and cardiorespiratory fitness in adults with ankylosing spondylitis: a cross-sectional controlled study. Rheumatol Int. 2015 Nov;35(11):1863-72. doi: 10.1007/s00296-015-3339-5. Epub 2015 Aug 9.
- Kang R, Passalent L, Morton R, Hawke C, Blair J, Lake A, et al. The European league against rheumatism (EULAR) 2013. Utilization of an informational needs assessment to develop an education program for patients with ankylosing spondylitis and related axial spondyloarthritis
- O'Dwyer T, O'Shea F, Wilson F. Physical activity in spondyloarthritis: a systematic review. Rheumatol Int. 2015 Mar;35(3):393-404. doi: 10.1007/s00296-014-3141-9. Epub 2014 Oct 10. Review.
- Sechrist KR, Walker SN, Pender NJ. Development and psychometric evaluation of the exercise benefits/barriers scale. Res Nurs Health. 1987 Dec;10(6):357-65.
- O'Dwyer T, Rafferty T, O'Shea F, Gissane C, Wilson F. Physical activity guidelines: is the message getting through to adults with rheumatic conditions? Rheumatology (Oxford). 2014 Oct;53(10):1812-7. doi: 10.1093/rheumatology/keu177. Epub 2014 May 14.
- Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol (1985). 2007 Jan;102(1):368-73. Epub 2006 Oct 19.
- Passalent L, Kang R, Lawson D, Hawke C, Omar A, Thavaneswaran A, Haroon N, Inman RD. Impact of e-learning on knowledge, self-efficacy and exercise behaviours in patients with axial spondyloarthritis: results from a longitudinal randomized control trial [abstract]. Arthritis Rheumatol. 2016;68 (suppl 10)
- Oosterom N, Gant CM, Ruiterkamp N, van Beijnum BF, Hermens H, Bakker SJL, Navis G, Vollenbroek-Hutten MMR, Laverman GD. Physical Activity in Patients With Type 2 Diabetes: The Case for Objective Measurement in Routine Clinical Care. Diabetes Care. 2018 Apr;41(4):e50-e51. doi: 10.2337/dc17-2041. Epub 2018 Feb 6.
- Calin A, Garrett S, Whitelock H, Kennedy LG, O'Hea J, Mallorie P, Jenkinson T. A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol. 1994 Dec;21(12):2281-5.
- Stoyanov SR, Hides L, Kavanagh DJ, Zelenko O, Tjondronegoro D, Mani M. Mobile app rating scale: a new tool for assessing the quality of health mobile apps. JMIR Mhealth Uhealth. 2015 Mar 11;3(1):e27. doi: 10.2196/mhealth.3422.
- Ward MM, Deodhar A, Akl EA, Lui A, Ermann J, Gensler LS, Smith JA, Borenstein D, Hiratzka J, Weiss PF, Inman RD, Majithia V, Haroon N, Maksymowych WP, Joyce J, Clark BM, Colbert RA, Figgie MP, Hallegua DS, Prete PE, Rosenbaum JT, Stebulis JA, van den Bosch F, Yu DT, Miller AS, Reveille JD, Caplan L. American College of Rheumatology/Spondylitis Association of America/Spondyloarthritis Research and Treatment Network 2015 Recommendations for the Treatment of Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis. Arthritis Rheumatol. 2016 Feb;68(2):282-98. doi: 10.1002/art.39298. Epub 2015 Sep 24.
- Mayer JE, Fontelo P. Meta-analysis on the effect of text message reminders for HIV-related compliance. AIDS Care. 2017 Apr;29(4):409-417. doi: 10.1080/09540121.2016.1214674. Epub 2016 Aug 1. Review.
- Fabre S, Molto A, Dadoun S, Rein C, Hudry C, Kreis S, Fautrel B, Pertuiset E, Gossec L. Physical activity in patients with axial spondyloarthritis: a cross-sectional study of 203 patients. Rheumatol Int. 2016 Dec;36(12):1711-1718. Epub 2016 Sep 24.
- van der Heijde D, Calin A, Dougados M, Khan MA, van der Linden S, Bellamy N. Selection of instruments in the core set for DC-ART, SMARD, physical therapy, and clinical record keeping in ankylosing spondylitis. Progress report of the ASAS Working Group. Assessments in Ankylosing Spondylitis. J Rheumatol. 1999 Apr;26(4):951-4. Review.
- Braun V, Clarke V. Using thematic analysis in psychology. Qualitative Research In Psychology 2008;3(2):77-101
- Haroon NN, Paterson JM, Li P, Inman RD, Haroon N. Patients With Ankylosing Spondylitis Have Increased Cardiovascular and Cerebrovascular Mortality: A Population-Based Study. Ann Intern Med. 2015 Sep 15;163(6):409-16. doi: 10.7326/M14-2470.
- Stock MS, Mota JA, DeFranco RN, Grue KA, Jacobo AU, Chung E, Moon JR, DeFreitas JM, Beck TW. The time course of short-term hypertrophy in the absence of eccentric muscle damage. Eur J Appl Physiol. 2017 May;117(5):989-1004. doi: 10.1007/s00421-017-3587-z. Epub 2017 Mar 20.
- Arends S, Hofman M, Kamsma YP, van der Veer E, Houtman PM, Kallenberg CG, Spoorenberg A, Brouwer E. Daily physical activity in ankylosing spondylitis: validity and reliability of the IPAQ and SQUASH and the relation with clinical assessments. Arthritis Res Ther. 2013 Aug 23;15(4):R99. doi: 10.1186/ar4279.
- Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol. 1994 Dec;21(12):2286-91.
- Foster C, Richards J, Thorogood M, Hillsdon M. Remote and web 2.0 interventions for promoting physical activity. Cochrane Database Syst Rev. 2013 Sep 30;9:CD010395.
- Rausch Osthoff AK, Niedermann K, Braun J, Adams J, Brodin N, Dagfinrud H, Duruoz T, Esbensen BA, Gunther KP, Hurkmans E, Juhl CB, Kennedy N, Kiltz U, Knittle K, Nurmohamed M, Pais S, Severijns G, Swinnen TW, Pitsillidou IA, Warburton L, Yankov Z, Vliet Vlieland TPM. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. Ann Rheum Dis. 2018 Sep;77(9):1251-1260. doi: 10.1136/annrheumdis-2018-213585. Epub 2018 Jul 11.
- Orr JA, King RJ. Mobile phone SMS messages can enhance healthy behaviour: a meta-analysis of randomised controlled trials. Health Psychol Rev. 2015;9(4):397-416. doi: 10.1080/17437199.2015.1022847. Epub 2015 May 28.
- Doward LC, Spoorenberg A, Cook SA, Whalley D, Helliwell PS, Kay LJ, McKenna SP, Tennant A, van der Heijde D, Chamberlain MA. Development of the ASQoL: a quality of life instrument specific to ankylosing spondylitis. Ann Rheum Dis. 2003 Jan;62(1):20-6. doi: 10.1136/ard.62.1.20.
- Sechrist KR, Walker SN, Pender NJ. Development and psychometric evaluation of the exercise benefits/barriers scale. Res Nurs Health. 1987 Dec;10(6):357-65. doi: 10.1002/nur.4770100603.
- Trost SG, McIver KL, Pate RR. Conducting accelerometer-based activity assessments in field-based research. Med Sci Sports Exerc. 2005 Nov;37(11 Suppl):S531-43. doi: 10.1249/01.mss.0000185657.86065.98.
- van der Heijde D, Ramiro S, Landewe R, Baraliakos X, Van den Bosch F, Sepriano A, Regel A, Ciurea A, Dagfinrud H, Dougados M, van Gaalen F, Geher P, van der Horst-Bruinsma I, Inman RD, Jongkees M, Kiltz U, Kvien TK, Machado PM, Marzo-Ortega H, Molto A, Navarro-Compan V, Ozgocmen S, Pimentel-Santos FM, Reveille J, Rudwaleit M, Sieper J, Sampaio-Barros P, Wiek D, Braun J. 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. Ann Rheum Dis. 2017 Jun;76(6):978-991. doi: 10.1136/annrheumdis-2016-210770. Epub 2017 Jan 13.
- Rudwaleit M, van der Heijde D, Landewe R, Listing J, Akkoc N, Brandt J, Braun J, Chou CT, Collantes-Estevez E, Dougados M, Huang F, Gu J, Khan MA, Kirazli Y, Maksymowych WP, Mielants H, Sorensen IJ, Ozgocmen S, Roussou E, Valle-Onate R, Weber U, Wei J, Sieper J. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009 Jun;68(6):777-83. doi: 10.1136/ard.2009.108233. Epub 2009 Mar 17. Erratum In: Ann Rheum Dis. 2019 Jun;78(6):e59.
- Sieper J, Rudwaleit M, Baraliakos X, Brandt J, Braun J, Burgos-Vargas R, Dougados M, Hermann KG, Landewe R, Maksymowych W, van der Heijde D. The Assessment of SpondyloArthritis international Society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009 Jun;68 Suppl 2:ii1-44. doi: 10.1136/ard.2008.104018.
- Hillsdon M, Foster C, Thorogood M. Interventions for promoting physical activity. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD003180. doi: 10.1002/14651858.CD003180.pub2.
- Wendel-Vos GC, Schuit AJ, Saris WH, Kromhout D. Reproducibility and relative validity of the short questionnaire to assess health-enhancing physical activity. J Clin Epidemiol. 2003 Dec;56(12):1163-9. doi: 10.1016/s0895-4356(03)00220-8.
- Seynnes OR, de Boer M, Narici MV. Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training. J Appl Physiol (1985). 2007 Jan;102(1):368-73. doi: 10.1152/japplphysiol.00789.2006. Epub 2006 Oct 19.
- Dagfinrud H, Kvien TK, Hagen KB. Physiotherapy interventions for ankylosing spondylitis. Cochrane Database Syst Rev. 2008 Jan 23;2008(1):CD002822. doi: 10.1002/14651858.CD002822.pub3.
- Klingberg E, Lorentzon M, Mellstrom D, Geijer M, Gothlin J, Hilme E, Hedberg M, Carlsten H, Forsblad-d'Elia H. Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment. Arthritis Res Ther. 2012 May 8;14(3):R108. doi: 10.1186/ar3833.
- Feldtkeller E, Vosse D, Geusens P, van der Linden S. Prevalence and annual incidence of vertebral fractures in patients with ankylosing spondylitis. Rheumatol Int. 2006 Jan;26(3):234-9. doi: 10.1007/s00296-004-0556-8. Epub 2005 Mar 11.
- Dursun N, Sarkaya S, Ozdolap S, Dursun E, Zateri C, Altan L, Birtane M, Akgun K, Revzani A, Aktas I, Tastekin N, Celiker R. Risk of falls in patients with ankylosing spondylitis. J Clin Rheumatol. 2015 Mar;21(2):76-80. doi: 10.1097/RHU.0000000000000216.
- O'Dwyer T, O'Shea F, Wilson F. Physical activity in spondyloarthritis: a systematic review. Rheumatol Int. 2015 Mar;35(3):393-404. doi: 10.1007/s00296-014-3141-9. Epub 2014 Oct 10.
- Jahangiry L, Farhangi MA, Shab-Bidar S, Rezaei F, Pashaei T. Web-based physical activity interventions: a systematic review and meta-analysis of randomized controlled trials. Public Health. 2017 Nov;152:36-46. doi: 10.1016/j.puhe.2017.06.005. Epub 2017 Jul 20.
- Marcolino MS, Oliveira JAQ, D'Agostino M, Ribeiro AL, Alkmim MBM, Novillo-Ortiz D. The Impact of mHealth Interventions: Systematic Review of Systematic Reviews. JMIR Mhealth Uhealth. 2018 Jan 17;6(1):e23. doi: 10.2196/mhealth.8873.
- Mayer JE, Fontelo P. Meta-analysis on the effect of text message reminders for HIV-related compliance. AIDS Care. 2017 Apr;29(4):409-417. doi: 10.1080/09540121.2016.1214674. Epub 2016 Aug 1.
- Foster C, Richards J, Thorogood M, Hillsdon M. Remote and web 2.0 interventions for promoting physical activity. Cochrane Database Syst Rev. 2013 Sep 30;9(9):CD010395. doi: 10.1002/14651858.CD010395.pub2.
- Fabre S, Molto A, Dadoun S, Rein C, Hudry C, Kreis S, Fautrel B, Pertuiset E, Gossec L. Physical activity in patients with axial spondyloarthritis: a cross-sectional study of 203 patients. Rheumatol Int. 2016 Dec;36(12):1711-1718. doi: 10.1007/s00296-016-3565-5. Epub 2016 Sep 24.
- Oosterom N, Gant CM, Ruiterkamp N, van Beijnum BF, Hermens H, Bakker SJL, Navis G, Vollenbroek-Hutten MMR, Laverman GD. Physical Activity in Patients With Type 2 Diabetes: The Case for Objective Measurement in Routine Clinical Care. Diabetes Care. 2018 Apr;41(4):e50-e51. doi: 10.2337/dc17-2041. Epub 2018 Feb 6. No abstract available.
- van der Heijde D, Calin A, Dougados M, Khan MA, van der Linden S, Bellamy N. Selection of instruments in the core set for DC-ART, SMARD, physical therapy, and clinical record keeping in ankylosing spondylitis. Progress report of the ASAS Working Group. Assessments in Ankylosing Spondylitis. J Rheumatol. 1999 Apr;26(4):951-4.
- Laura Passalent 2022. "Health Technology to Improve Exercise in axSpA". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05504616.
Frequently Asked Questions
What aims are being pursued with this experimental research?
"This clinical trial will measure its progress over a twelve-week period, with the primary goal being to evaluate changes in physical activity among participants through the International Physical Activity Questionnaire-Short Form questionnaire (IPAQ-SF). Additionally, secondary outcomes include alterations in disease severity using the Bath Ankylosing Spondylitis Disease Activity Index (BASDI) questionnaire and assessing patient acceptance of technology based interventions by way of Mobile Application Rating Scale." - Anonymous Online Contributor
Unverified Answer
How many participants is the clinical trial recruiting?
"Affirmative. Data hosted on clinicaltrials.gov certify that this medical experiment, which was originally posted on July 21st 2022, is presently enrolling participants. Approximately 106 individuals must be recruiter from a single facility." - Anonymous Online Contributor
Unverified Answer
Is participation in this clinical trial still an option for potential volunteers?
"Affirmative. The data hosted on clinicaltrials.gov demonstrates that enrollment is still ongoing for this medicinal research, which was initially posted on July 21st 2022 and recently changed on November 2nd 2022. 106 individuals need to be brought into the study from 1 centre." - Anonymous Online Contributor
Unverified Answer