Multiple Treatments for Brain Injury
What You Need to Know Before You Apply
What is the purpose of this trial?
The Special Operations Care-Fund (SOC-F) will sponsor the application of four treatments - hormone replacement, magnetic resonance brain stimulation, ibogaine, and 5-Meo-DMT - to Special Operations Forces veterans with a history of combat deployments, traumatic brain injury, and problems with mental health and cognitive functioning. An observational study will be conducted in parallel by the Johns Hopkins Center for Psychedelic and Consciousness Research to determine the effectiveness and safety of each treatment, primarily through measuring post-treatment changes in PTSD symptoms and cognitive functioning.
Will I have to stop taking my current medications?
The trial requires participants to stop taking selective serotonin reuptake inhibitor (SSRI) medications. If you are on SSRIs, you must be willing to taper off them to join the study.
Is hormone replacement therapy (HRT) generally safe for humans?
How does the treatment for brain injury using 5-MeO-DMT, HRT, ibogaine with magnesium, and MeRT differ from other treatments?
This treatment is unique because it combines psychedelic substances like 5-MeO-DMT and ibogaine, which may promote brain healing through neuroplasticity (the brain's ability to reorganize itself) and neurogenesis (the growth of new brain cells), with hormone replacement and magnetic resonance therapy, offering a multi-faceted approach to address the complex nature of brain injuries.678910
What data supports the effectiveness of the drug 5-MeO-DMT for brain injury?
Who Is on the Research Team?
Sandeep Nayak, MD
Principal Investigator
Johns Hopkins University
Are You a Good Fit for This Trial?
This trial is for Special Operations Forces veterans aged 18 or older with a history of combat deployments and brain injuries, who are experiencing mental health and cognitive issues. It's not open to those with severe psychiatric disorders, major organ dysfunction, recent surgeries, abnormal blood tests, or unwillingness to stop taking SSRI medications.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a sequence of treatments including Hormone Replacement Therapy, Magnetic e-Resonance Therapy, Ibogaine, and 5-MeO-DMT
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- 5-MeO-DMT
- Hormone Replacement Therapy (HRT)
- ibogaine with magnesium treatment
- Magnetic Resonance Therapy (MeRT)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johns Hopkins University
Lead Sponsor
Special Operators Care Fund
Collaborator