Order 4 for Stroke (OptiMUS Trial)

"For this research project, individuals aged between 18 and 75 are eligible for participation. Notably, there exist a total of 40 trials catering to those under 18 years old and an additional 1078 targeting participants over the age of 65."

"Indeed, the information available on clinicaltrials.gov indicates that this investigation is actively pursuing eligible candidates. The trial was initially disclosed on February 16th, 2024 and underwent its latest revision on the same day. There is a need to recruit 70 participants from one designated site."

"Indeed, clinicaltrials.gov data affirms the ongoing patient recruitment for this investigation. The trial was first listed on 2/16/2024 and most recently revised on the same date. A total of 70 participants are sought from a single site."

"The primary goal of the research, to be evaluated within approximately 3 hours on Day 1, is to examine Neural Activation in the Primary Motor Cortex during a task involving No Improvisation and Live Accompaniment. Secondary objectives include assessing participants' cognitive challenge levels using a Music Playing Self-Report Questionnaire during tasks without improvisation or live accompaniment. Functional Connectivity with the Ventral Striatum will also be examined under similar conditions through functional MRI (fMRI) analysis utilizing Psychophysiological interactions (PPI). Additionally, Neural Activation in the Amygdala will be scrutinized during activities that involve No Improvisation paired"

"The research study is recruiting 70 individuals aged between 18 and 75 who have experienced a stroke. Eligible participants should meet the following criteria: be within the specified age range, exhibit minimal resistance to wrist extensor muscle movement - scoring <2 on the Ashworth Scale (Brashear et al., 2002), demonstrate hemiparesis due to a stroke that occurred at least six months prior (either ischemic or hemorrhagic), possess independent mobility of the wrist flexor and extensor muscles without assistance from the unaffected side, achieve an MRC score above 3 for muscle strength indicating active motion against gravity, maintain an"