Dyed vs. Undyed Sutures for Wound Closure
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether dyed or undyed sutures (Polyglactin 910) result in better wound healing after surgery. Researchers aim to determine if dyed sutures cause more skin reactions, such as redness, itching, or scarring, compared to undyed ones. The study uses a split-wound design, applying both suture types to different parts of the same wound for comparison. Participants should be individuals scheduled for routine surgical procedures. As an unphased trial, this study provides participants the chance to contribute to valuable research that could enhance surgical outcomes for future patients.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that these sutures are safe for wound closure?
Studies have shown that Polyglactin 910 stitches, both colored and uncolored, are safe for patients. Those who have used these stitches have healed completely without infections or complications at the surgery site, indicating their safety for closing surgical wounds. The stitches maintain strength over time, aiding the healing process.
The colored stitches are violet and are just as safe as the uncolored ones. Both types dissolve naturally in the body, typically within two months, eliminating the need for another procedure to remove them.
Overall, both colored and uncolored Polyglactin 910 stitches have a strong record of safety and effectiveness for closing wounds.12345Why are researchers excited about this trial?
Researchers are excited about the trial comparing dyed and undyed sutures for wound closure because it explores whether the color of sutures impacts healing and visibility during surgery. Polyglactin 910, known as Vicryl, is a popular absorbable suture material that comes in both violet (dyed) and undyed forms. This study aims to determine if the dyed version offers better visibility for surgeons, which could lead to more precise stitching and potentially improved healing outcomes. Additionally, the comparison might reveal if undyed sutures cause less tissue reaction, which could be beneficial for patients with sensitive skin.
What evidence suggests that dyed and undyed sutures could be effective for wound healing?
Studies have shown that both dyed and undyed Polyglactin 910 stitches are strong and reliable for closing wounds. They maintain their strength for up to 10 days and begin to weaken noticeably by day 14. Research indicates that these stitches, whether dyed or undyed, help wounds heal completely within 30 days without major issues like infections. Evidence suggests that stitches with a special coating can help prevent infections, although this feature is not part of this trial. In this trial, participants will receive either dyed or undyed sutures to determine if dyed stitches cause more skin irritation than undyed ones. Overall, both types of stitches effectively heal wounds.14678
Who Is on the Research Team?
Sarah Camplbell, MD
Principal Investigator
West Virginia University-Dermatology
Are You a Good Fit for This Trial?
This trial is for patients scheduled for standard surgical excision and aims to explore the skin's reaction to two types of sutures. It excludes those who do not meet the criteria for a routine surgery.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo cutaneous surgery with dyed and undyed polyglactin sutures to evaluate skin reactions
Follow-up
Participants are monitored for wound healing and tissue reactivity at 2 weeks, 4 weeks, and 3 months post-surgery
What Are the Treatments Tested in This Trial?
Interventions
- Polyglactin 910 (Dyed)
- Polyglactin 910 (Undyed)
Find a Clinic Near You
Who Is Running the Clinical Trial?
West Virginia University
Lead Sponsor