Ventilated Cigarette Filter for Tobacco Use

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Tobacco Use
Ventilated Cigarette Filter - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effects of different degrees of cigarette filter ventilation on biomarkers of exposure to toxins and on smoking behavior. Additionally, the study will explore how these changes impact a smoker's dependence on cigarettes and their subjective responses to smoking.

Treatment Effectiveness

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: 7 days prior to baseline visit and 7 days prior to week 6 visit

6 weeks
Change in Total NNAL: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
Week 6
Change in cigarettes per day (CPD)

Trial Safety

Trial Design

2 Treatment Groups

Ventilated Cigarette Filter
1 of 2
Unventilated Cigarette Filter
1 of 2
Experimental Treatment

184 Total Participants · 2 Treatment Groups

Primary Treatment: Ventilated Cigarette Filter · No Placebo Group · N/A

Ventilated Cigarette Filter
Other
Experimental Group · 1 Intervention: Ventilated Cigarette Filter · Intervention Types: Other
Unventilated Cigarette Filter
Other
Experimental Group · 1 Intervention: Unventilated Cigarette Filter · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 7 days prior to baseline visit and 7 days prior to week 6 visit

Who is running the clinical trial?

Ohio State UniversityOTHER
704 Previous Clinical Trials
382,119 Total Patients Enrolled
2 Trials studying Tobacco Use
118 Patients Enrolled for Tobacco Use
Masonic Cancer Center, University of MinnesotaLead Sponsor
253 Previous Clinical Trials
14,886 Total Patients Enrolled
4 Trials studying Tobacco Use
288 Patients Enrolled for Tobacco Use
Dorothy K Hatsukami, Ph.DPrincipal InvestigatorMasonic Cancer Center, University of Minnesota
2 Previous Clinical Trials
168 Total Patients Enrolled
1 Trials studying Tobacco Use
118 Patients Enrolled for Tobacco Use

Eligibility Criteria

Age 18+ · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are at least 21 years old.
You are a regular cigarette smoker.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 31st, 2021

Last Reviewed: October 16th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.