Thrivorship Program for Traumatic Injury Survivors

Overseen By Marissa A Boeck, MD, MPH

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of California, San Francisco

Disqualifiers: Under 18, Deceased, Unable consent

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new support pathway, the Human-Centered Injury Thrivorship Pathway, for individuals recovering from physical injuries. The researchers aim to determine if this program effectively meets the medical and social needs of participants and if it is user-friendly. Participants will engage in interviews, and their use of the program's resources will be monitored. This trial suits individuals hospitalized for a physical injury at Zuckerberg San Francisco General Hospital who reside in San Francisco. As an unphased trial, it offers participants the chance to contribute to innovative research that could enhance recovery pathways for future patients.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this pathway is safe for injury survivors?

This trial explores a new treatment called the Human-Centered Injury Thrivorship Pathway. As an early-stage study, it aims to observe initial responses to this approach. Limited safety information may be available at this stage.

The pathway offers a holistic, person-focused approach, integrating various medical specialties to support injury survivors. While specific safety data from past studies is not available, the goal is to develop a supportive and comprehensive care model that is both safe and manageable. Researchers will closely monitor participants, using their feedback to refine the pathway and ensure it effectively and safely meets the needs of injury survivors. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Unlike traditional treatments for traumatic injury recovery, which often focus on physical rehabilitation and medication, the Human-Centered Injury Thrivorship Pathway takes a holistic approach. This innovative method emphasizes the emotional and psychological well-being of survivors, aiming to improve overall quality of life. Researchers are excited because it could offer a more comprehensive road to recovery, addressing both mental and physical aspects of healing, which are often overlooked in standard care.

What evidence suggests that the Human-Centered Injury Thrivorship Pathway is effective for injury survivors?

Research has shown that structured care plans, such as the Human-Centered Injury Thrivorship Pathway used in this trial, can enhance recovery for injured individuals. These plans address each person's unique needs and situations, facilitating access to necessary support. Early findings suggest that tailoring care to specific needs leads to better health outcomes and greater satisfaction. Patients often find these personalized plans more acceptable and easier to follow. This approach effectively addresses both medical and social needs, promoting more complete healing after an injury. ^{1 2 6 7 8}

Who Is on the Research Team?

Marissa A Boeck, MD, MPH

Principal Investigator

University of California, San Francisco

Are You a Good Fit for This Trial?

This trial is for individuals who have survived physical trauma and are navigating their recovery. It's designed to assess a new support pathway tailored to both medical and social needs of these survivors. Participants should be willing to engage in interviews and allow tracking of their use of the provided resources.

Inclusion Criteria

Patient must be a San Francisco resident or unhoused in San Francisco

I understand the details of the clinical trial and can consent to participate.

I must stay in the hospital for at least 24 hours.

Exclusion Criteria

Patient must have deceased during index hospitalization

I am unable to understand and give consent for my own treatment.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pathway Enrollment

Participants are enrolled in the human-centered injury thrivorship pathway and participate in in-depth interviews

8-12 weeks

Follow-up

Participants are monitored for pathway resource utilization and engagement

up to 1 year

What Are the Treatments Tested in This Trial?

Interventions

• Human-Centered Injury Thrivorship Pathway

Trial Overview The study is testing a 'Human-Centered Injury Thrivorship Pathway' which aims to help injury survivors with their recovery process. The focus is on determining if this pathway is suitable, well-received, and practical for addressing the comprehensive needs of these individuals.

How Is the Trial Designed?

Group I: Injury Thrivorship Pathway Experimental Treatment 1 Intervention

Enrollment in the human-centered injury thrivorship pathway.

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials

2,636

Recruited

19,080,000+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials

394

Recruited

404,000+

Published Research Related to This Trial

In a study of 193 pediatric patients with severe traumatic brain injury (sTBI), 53% experienced at least one adverse event (AE), highlighting the high risk of complications in this vulnerable population.

The most common AE was decubitus ulcers, and patients with AEs had longer hospital stays and higher costs, indicating that identifying and preventing AEs can improve patient safety and reduce healthcare expenses.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Identification of adverse events in pediatric severe traumatic brain injury patients to target evidence-based prevention for increased performance improvement and patient safety. Charyk Stewart, T., Luong, K., Alharfi, I., et al.[2021]

In a Level II trauma center, 86% of adult trauma patients enrolled in the Trauma Resilience and Recovery Program (TRRP), indicating strong initial engagement despite fewer resources compared to Level I centers.

However, only 30% of patients completed mental health screenings during follow-up, suggesting a need for program adaptations to enhance ongoing engagement and address mental health needs more effectively.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Implementation of a stepped care program to address posttraumatic stress disorder and depression in a Level II trauma center. Espeleta, HC., Litvitskiy, NS., Higgins, K., et al.[2023]

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT06292039

Human-centered Injury Thrivorship Pathway for Survivors ... The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors. The main question it aims to answer is ...

2. clinicaltrials.gov clinicaltrials.gov/study/NCT06292039?aggFilters=funderType:nih,status:rec%20not%20ava&cond=trauma&rank=2

Human-centered Injury Thrivorship Pathway for Survivors ... The primary outcome will be qualitative data from in-depth semi-structured interviews linked to participant demographic and clinical information. The secondary ...

3. withpower.com withpower.com/trial/phase-wounds-and-injuries-6-2025-47053

Thrivorship Program for Traumatic Injury Survivors What data supports the effectiveness of the treatment Human-Centered Injury Thrivorship Pathway? Research shows that using a structured care plan, like a ...

4. clinicaltrials.ucsf.edu clinicaltrials.ucsf.edu/injury-traumatic

UCSF Injury Traumatic Clinical Trials for 2025 The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors.

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC7286246/

The impact of trauma systems on patient outcomes - PMC Inappropriate undertriage to a nondesignated trauma center has been associated with a 30% increase in mortality within the first 48 hours.

6. clinicaltrials.ucsf.edu clinicaltrials.ucsf.edu/trial/NCT06292039

Human-centered Injury Thrivorship Pathway for Survivors of ... The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors. The main question it aims to answer is ...

7. reporter.nih.gov reporter.nih.gov/search/15E9CC084888C6D27598B8961CAA4A01A2FFCEB861BF/project-details/10913519

Institutional Career Development Core Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma Study, NOT YET RECRUITING. Core NIH Project Number, ClinicalTrials.gov ID, Study ...

8. generalsurgery.ucsf.edu generalsurgery.ucsf.edu/bio/marissa-boeck-md-mph

Marissa A. Boeck, MD, MPH - UCSF : General Surgery Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma (NCT06292039). Related Conditions: Injury Traumatic, Survivorship, Trauma Injury ...