HIV Prevention Program for Older Black Women

Overseen By Laneshia Conner, PhD

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: Laneshia Conner

Disqualifiers: Pre-menopausal, Cognitive impairment

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 6

Duration: 4 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a group-based program can enhance HIV knowledge, prevention behaviors, and testing among older Black women living in subsidized housing. Participants will either begin the program immediately (Adapted W2W) or after a short wait, engaging in discussions and activities over several weeks. The trial seeks to assess whether this tailored approach is effective and engaging for the women involved. Women who are 50 or older, live in certain areas, and identify as Black or African American may be suitable candidates. As an unphased trial, this study provides participants the opportunity to contribute to research that could lead to more effective community health programs.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on group discussions and education rather than medication changes.

What prior data suggests that this HIV prevention program is safe for older Black women?

Research shows that participants generally like the Adapted Woman-2-Woman (W2W) program. In earlier studies, women who joined similar programs reported satisfaction and regular attendance, indicating the program is engaging and manageable. These studies have not reported major negative effects or adverse reactions.

This trial involves a behavioral program focused on teaching and skills rather than medicine, typically resulting in fewer safety concerns compared to trials with new drugs. Overall, previous research suggests the Adapted W2W program is safe and easy to handle. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Adapted W2W program because it specifically targets older Black women, a group often overlooked in HIV prevention efforts. Unlike standard prevention methods that might not consider age-related factors, this program includes educational sessions that address aging-related HIV knowledge and prevention practices. By focusing on these tailored interventions, the program aims to reduce HIV transmission within this demographic, offering a culturally and age-sensitive approach that current treatments may lack.

What evidence suggests that this HIV prevention program is effective for older Black women?

Research shows that the "Woman-2-Woman" (W2W) program, which participants in this trial may receive, is a promising new version of an HIV prevention program for older Black women. This program specifically addresses their unique experiences and needs. Studies have found that similar programs can increase knowledge about HIV and improve prevention behaviors. Participants in earlier versions of the program reported high satisfaction and greater awareness of HIV risks and prevention methods. This suggests that the updated W2W program could encourage older Black women to use condoms more frequently and get tested for HIV. Overall, the evidence supports the potential success of this customized approach. ^{1 6 7 8 9}

Who Is on the Research Team?

Laneshia Conner, PhD

Principal Investigator

University of Kentucky

Are You a Good Fit for This Trial?

This trial is for older Black women aged 50 and above living in subsidized housing. It's designed to see if a group-based HIV prevention program can help them learn more about HIV, use condoms, and get tested. Participants should be willing to share their reproductive health history and sexual health decisions.

Inclusion Criteria

A resident of Selected sites

A MOCA score of less than 24

English speaking

Exclusion Criteria

Cognitive impairment

I have not gone through menopause.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants take part in a group-based HIV prevention program with four weekly sessions including group discussions, education, and skill-building activities

4 weeks

4 visits (in-person)

Follow-up

Participants complete questionnaires to assess HIV knowledge, condom use, and testing behavior

4 weeks

2 visits (in-person)

Open-label extension (optional)

Participants in the waitlist control group receive the intervention 8 weeks after the initial group

8 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Adapted W2W
• Waitlist Control

Trial Overview The study tests the Woman-2-Woman (W2W) intervention against a waitlist control group. Women will either start the program immediately or after a 4-week waiting period. The program includes four weekly sessions with discussions, education, and skill-building focused on HIV prevention tailored to their experiences.

How Is the Trial Designed?

Group I: Adapted W2W Experimental Treatment 1 Intervention

HIV intervention focused on aging-related HIV knowledge, identifying HIV prevention practices, and reducing HIV transmission. Intervention given in four, 2 hour educational sessions with a fifth booster session and a final follow up session.

Group II: Waitlist Control Active Control 1 Intervention

This group will receive the intervention 8 weeks after the W2W intervention group completes their follow-up and in the same pattern.

Who Is Running the Clinical Trial?

Laneshia Conner

Lead Sponsor

National Institute on Aging (NIA)

Collaborator

Trials

1,841

Recruited

28,150,000+

Citations

1. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/28467279/

Adapting an HIV risk reduction intervention for older women This article describes the process of adapting and piloting W2W based on recommendations from existing HIV prevention research. Six older women, all of whom had ...

2. researchgate.net researchgate.net/publication/5659333_Adaptation_of_an_HIV_Prevention_Curriculum_for_Use_With_Older_African_American_Women

Adaptation of an HIV Prevention Curriculum for Use With ... This study adapted an HIV risk reduction curriculum for use with older African American women based on input from a sample of women from the ...

3. academia.edu academia.edu/85095632/Woman_to_Woman_W2W_Adapting_an_HIV_risk_reduction_intervention_for_older_women

Adapting an HIV risk reduction intervention for older women Participants described satisfaction with the program and had high rates of attendance; observations regarding the measures suggest the need to further develop ...

4. formative.jmir.org formative.jmir.org/2022/5/e34041/

An Evidence-Based HIV Risk–Reduction Intervention for ... African American women have experienced an unparalleled burden of HIV since the start of the epidemic and currently account for 55% of new HIV ...

5. guilfordjournals.com guilfordjournals.com/doi/10.1521/aeap.2006.18.supp.161

Enhancing Adoption of Evidence–Based HIV Interventions This article examines how promotion of a suite of HIV interventions for African American females may facilitate adoption of the three evidence–based HIV ...

6. researchgate.net researchgate.net/publication/316670272_Woman_to_Woman_W2W_Adapting_an_HIV_risk_reduction_intervention_for_older_women

Adapting an HIV risk reduction intervention for older women Participants described satisfaction with the program and had high rates of attendance; observations regarding the measures suggest the need to further develop ...

7. clinicaltrials.gov clinicaltrials.gov/study/NCT01111721

Study Details | NCT01111721 | Project POWER, Adapting ... Project POWER will test the efficacy of a multi-session HIV Prevention program, adapted from an existing program (Project SAFE), for incarcerated women in the ...

8. researchgate.net researchgate.net/publication/266783229_Collaborative_effort_of_HIV_domestic_violence_and_homeless_service_organizations_to_develop_integrated_services_as_strategy_for_HIV_risk_reduction_for_women

Collaborative effort of HIV, domestic violence and homeless ... This article describes the process of adapting and piloting W2W based on recommendations from existing HIV prevention research. Six older women, all of whom ...

9. scienceon.kisti.re.kr scienceon.kisti.re.kr/srch/selectPORSrchArticle.do?cn=NART90505235

Adapting an HIV risk reduction intervention for older women [해외논문] Woman to Woman (W2W): Adapting an HIV risk reduction intervention for older women. Journal of women & aging, v.30 no.5, 2018년, pp.428 - 443.