Stepped Collaborative Care for PTSD
(TSOS 8 Trial)
Trial Summary
What is the purpose of this trial?
This investigation is a randomized pragmatic trial of a brief stepped care intervention delivered from an acute care medical trauma center that may both reduce the symptoms of posttraumatic stress disorder (PTSD) and diminish emergency department health service utilization.
Do I have to stop taking my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the idea that Stepped Collaborative Care for PTSD is an effective treatment?
The available research shows that Stepped Collaborative Care for PTSD can lead to significant improvements in symptoms. For example, in a study involving veterans, 42.2% of participants reported a noticeable improvement in their PTSD symptoms. Another study in the Military Health System found that this treatment improved PTSD and depression outcomes compared to usual care. Additionally, a trial with injured trauma survivors showed that the treatment led to modest symptom reductions, especially noticeable at 3 and 6 months after the intervention. These findings suggest that Stepped Collaborative Care can be an effective way to manage PTSD.12345
What safety data exists for Stepped Collaborative Care for PTSD?
The provided research does not directly address safety data for Stepped Collaborative Care for PTSD or its related terms. The studies focus on adverse events in neuropsychiatry, patient safety data sharing, mental health legislation, occupational well-being in pediatricians, and support for healthcare workers after serious adverse events. None of these specifically evaluate the safety of Stepped Collaborative Care for PTSD.678910
Research Team
Douglas Zatzick, MD
Principal Investigator
University of Washington
Eligibility Criteria
This trial is for adults over 18 who've been hospitalized for a traumatic injury, have high PTSD symptoms, and meet certain risk criteria. They must speak English or Spanish and live in specific Western US states. Excluded are those under 18, non-trauma patients, non-English/Spanish speakers, cognitively impaired individuals, prisoners, residents outside the specified states with insufficient contact info or safety concerns due to violence history.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a stepped collaborative care intervention including care management, medication, and psychotherapy targeting PTSD and comorbidity
Follow-up
Participants are monitored for safety and effectiveness after treatment with follow-up interviews at 1-, 3-, 6-, and 12-months post-injury
Treatment Details
Interventions
- American College of Surgeons (ACS) Required Screening and Referral (Usual Care)
- Stepped Collaborative Care
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Washington
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator